Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              22     103
NP_005973                                                              17    4312
NP_848519                                                              17    4312
NP_036251                                                              17    4312
NP_001034892                                                           17    4312
XP_006725684                                                           17    4312
XP_006725683                                                           17    4312
XP_006725682                                                           17    4312
XP_006725681                                                           17    4312
XP_006725680                                                           17    4312
XP_006725679                                                           17    4312
XP_006725332                                                           17    4312
XP_006725331                                                           17    4312
XP_006725330                                                           17    4312
XP_006725329                                                           17    4312
XP_006725328                                                           17    4312
XP_005257425                                                           17    4312
XP_005257424                                                           17    4312
XP_005257423                                                           17    4312
XP_005257422                                                           17    4312
XP_005257421                                                           17    4312
XP_005257419                                                           17    4312
XP_005251917                                                           17    4312
NP_055426                                                              16    5631
NP_055309                                                              16    5631
XP_006721103                                                           16    5631
XP_005255314                                                           16    5631
XP_006721102                                                           16    5631
XP_005255313                                                           16    5631
XP_005255312                                                           16    5631
XP_006721101                                                           16    5631
XP_005255311                                                           16    5631
XP_005255310                                                           16    5631
XP_005248757                                                           16    5631
XP_006715468                                                           16    5631
XP_005248756                                                           16    5631
XP_006715467                                                           16    5631
NP_071394                                                              16    7355
NP_001177410                                                           16    7355
NP_006030                                                              16    7355
NP_001157934                                                           16    7355
XP_005274671                                                           16    7355
XP_005274669                                                           16    7355
NP_003122                                                              15    9605
NP_001277251                                                           15    9605
NP_005500                                                              15    9605
NP_001277250                                                           15    9605
NP_004752                                                              15    9605
NP_001230667                                                           15    9605
XP_005275492                                                           15    9605
XP_005275491                                                           15    9605
XP_005275332                                                           15    9605
XP_005275331                                                           15    9605
XP_005275330                                                           15    9605
XP_005275063                                                           15    9605
XP_005275062                                                           15    9605
XP_005275061                                                           15    9605
XP_005272907                                                           15    9605
XP_005272906                                                           15    9605
XP_005272905                                                           15    9605
XP_005249315                                                           15    9605
XP_005249314                                                           15    9605
XP_005249313                                                           15    9605
XP_006714623                                                           15    9605
XP_005271970                                                           15    9605
XP_005271969                                                           15    9605
XP_005271967                                                           15    9605
XP_005271966                                                           15    9605
>NP_002430
          Length = 1137

 Score = 21.9 bits (45), Expect =   103
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FMTASMPTH 9
           FMTAS+PTH
Sbjct: 280 FMTASIPTH 288
>NP_005973
          Length = 284

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS P+H
Sbjct: 251 LTASQPSH 258
>NP_848519
          Length = 338

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   FMTASMPTH 9
           F TA +P H
Sbjct: 280 FFTAPLPAH 288
>NP_036251
          Length = 325

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   FMTASMPTH 9
           F TA +P H
Sbjct: 267 FFTAPLPAH 275
>NP_001034892
          Length = 346

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   FMTASMPTH 9
           F TA +P H
Sbjct: 288 FFTAPLPAH 296
>XP_006725684
          Length = 765

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_006725683
          Length = 796

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_006725682
          Length = 804

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 118 LTASLPQH 125
>XP_006725681
          Length = 831

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_006725680
          Length = 833

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 147 LTASLPQH 154
>XP_006725679
          Length = 862

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_006725332
          Length = 796

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_006725331
          Length = 804

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 118 LTASLPQH 125
>XP_006725330
          Length = 831

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_006725329
          Length = 833

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 147 LTASLPQH 154
>XP_006725328
          Length = 862

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_005257425
          Length = 765

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_005257424
          Length = 796

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_005257423
          Length = 804

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 118 LTASLPQH 125
>XP_005257422
          Length = 831

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_005257421
          Length = 833

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 147 LTASLPQH 154
>XP_005257419
          Length = 862

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MTASMPTH 9
           +TAS+P H
Sbjct: 176 LTASLPQH 183
>XP_005251917
          Length = 351

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   FMTASMPTH 9
           F TA +P H
Sbjct: 293 FFTAPLPAH 301
>NP_055426
          Length = 5596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+ TH
Sbjct: 4624 FLTMSLATH 4632
>NP_055309
          Length = 1962

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMTASMP 7
           FMT+S+P
Sbjct: 459 FMTSSLP 465
>XP_006721103
          Length = 1597

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMTASMP 7
           FMT+S+P
Sbjct: 427 FMTSSLP 433
>XP_005255314
          Length = 1709

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMTASMP 7
           FMT+S+P
Sbjct: 206 FMTSSLP 212
>XP_006721102
          Length = 1820

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMTASMP 7
           FMT+S+P
Sbjct: 317 FMTSSLP 323
>XP_005255313
          Length = 1822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMTASMP 7
           FMT+S+P
Sbjct: 427 FMTSSLP 433
>XP_005255312
          Length = 1871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMTASMP 7
           FMT+S+P
Sbjct: 427 FMTSSLP 433
>XP_006721101
          Length = 1907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMTASMP 7
           FMT+S+P
Sbjct: 427 FMTSSLP 433
>XP_005255311
          Length = 1913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMTASMP 7
           FMT+S+P
Sbjct: 459 FMTSSLP 465
>XP_005255310
          Length = 1919

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMTASMP 7
           FMT+S+P
Sbjct: 427 FMTSSLP 433
>XP_005248757
          Length = 3591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+ TH
Sbjct: 2619 FLTMSLATH 2627
>XP_006715468
          Length = 3744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+ TH
Sbjct: 2772 FLTMSLATH 2780
>XP_005248756
          Length = 3905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+ TH
Sbjct: 2933 FLTMSLATH 2941
>XP_006715467
          Length = 5550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+ TH
Sbjct: 4624 FLTMSLATH 4632
>NP_071394
          Length = 1339

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    FMTASMPTH 9
            FMT+  P H
Sbjct: 1311 FMTSPSPKH 1319
>NP_001177410
          Length = 1275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    FMTASMPTH 9
            FMT+  P H
Sbjct: 1247 FMTSPSPKH 1255
>NP_006030
          Length = 1479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMTASMP 7
            F+TAS+P
Sbjct: 1022 FITASLP 1028
>NP_001157934
          Length = 5335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   MTASMPTH 9
           + ASMP H
Sbjct: 602 LEASMPVH 609
>XP_005274671
          Length = 195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TASMPTH 9
          TAS+P H
Sbjct: 11 TASLPQH 17
>XP_005274669
          Length = 202

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TASMPTH 9
          TAS+P H
Sbjct: 11 TASLPQH 17
>NP_003122
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MTASMPT 8
           MT+S+PT
Sbjct: 395 MTSSVPT 401
>NP_001277251
          Length = 2854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+P +
Sbjct: 1379 FLTTSLPAY 1387
>NP_005500
          Length = 3027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+P +
Sbjct: 1552 FLTTSLPAY 1560
>NP_001277250
          Length = 3048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+P +
Sbjct: 1552 FLTTSLPAY 1560
>NP_004752
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>NP_001230667
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FMTASMPTH 9
          FM+A + TH
Sbjct: 34 FMSAFLATH 42
>XP_005275492
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FMTASMPTH 9
          FM+A + TH
Sbjct: 34 FMSAFLATH 42
>XP_005275491
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>XP_005275332
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FMTASMPTH 9
          FM+A + TH
Sbjct: 34 FMSAFLATH 42
>XP_005275331
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>XP_005275330
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>XP_005275063
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FMTASMPTH 9
          FM+A + TH
Sbjct: 34 FMSAFLATH 42
>XP_005275062
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>XP_005275061
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>XP_005272907
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FMTASMPTH 9
          FM+A + TH
Sbjct: 34 FMSAFLATH 42
>XP_005272906
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>XP_005272905
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>XP_005249315
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FMTASMPTH 9
          FM+A + TH
Sbjct: 34 FMSAFLATH 42
>XP_005249314
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>XP_005249313
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FMTASMPTH 9
           FM+A + TH
Sbjct: 116 FMSAFLATH 124
>XP_006714623
          Length = 1625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+P +
Sbjct: 1552 FLTTSLPAY 1560
>XP_005271970
          Length = 2931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+P +
Sbjct: 1552 FLTTSLPAY 1560
>XP_005271969
          Length = 3020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+P +
Sbjct: 1486 FLTTSLPAY 1494
>XP_005271967
          Length = 3065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+P +
Sbjct: 1552 FLTTSLPAY 1560
>XP_005271966
          Length = 3086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    FMTASMPTH 9
            F+T S+P +
Sbjct: 1552 FLTTSLPAY 1560
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.120    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 523,121
Number of extensions: 644
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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