Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              21     229
XP_006713721                                                           21     229
NP_001273596                                                           17    3301
NP_001273595                                                           17    3301
NP_001273594                                                           17    3301
NP_001129406                                                           17    3301
NP_001129407                                                           17    3301
NP_006466                                                              17    3301
NP_001129408                                                           17    3301
NP_003904                                                              17    3301
XP_005266289                                                           17    3301
XP_005266288                                                           17    3301
XP_006715301                                                           17    3301
XP_006710357                                                           17    3301
XP_005270425                                                           17    3301
XP_005270424                                                           17    3301
NP_001099000                                                           17    3301
NP_006358                                                              17    3301
NP_006357                                                              17    3301
NP_009123                                                              17    4312
NP_001191                                                              16    5631
NP_001005743                                                           16    5631
NP_003735                                                              16    5631
NP_001005745                                                           16    5631
NP_001005744                                                           16    5631
NP_056453                                                              16    5631
NP_955400                                                              16    5631
XP_006720359                                                           16    5631
XP_006720358                                                           16    5631
XP_006720357                                                           16    5631
XP_006720356                                                           16    5631
XP_006720355                                                           16    5631
XP_006720354                                                           16    5631
XP_006720353                                                           16    5631
XP_006720352                                                           16    5631
XP_006720351                                                           16    5631
XP_006720350                                                           16    5631
XP_006720349                                                           16    5631
XP_006720348                                                           16    5631
XP_005268203                                                           16    5631
XP_005268202                                                           16    5631
XP_005268201                                                           16    5631
XP_006720347                                                           16    5631
XP_005268200                                                           16    5631
XP_006720346                                                           16    5631
XP_005268199                                                           16    5631
NP_001244                                                              16    7355
NP_660215                                                              16    7355
NP_733936                                                              15    9605
NP_001071                                                              15    9605
NP_115287                                                              15    9605
NP_000615                                                              15    9605
NP_653277                                                              15    9605
NP_653248                                                              15    9605
NP_001036090                                                           15    9605
NP_066305                                                              15    9605
XP_006714508                                                           15    9605
XP_006714507                                                           15    9605
XP_005245262                                                           15    9605
XP_005245259                                                           15    9605
XP_005245257                                                           15    9605
XP_005245256                                                           15    9605
>NP_006209
          Length = 1068

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    FMKQMNDA 8
            FMKQMNDA
Sbjct: 1039 FMKQMNDA 1046
>XP_006713721
          Length = 1068

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    FMKQMNDA 8
            FMKQMNDA
Sbjct: 1039 FMKQMNDA 1046
>NP_001273596
          Length = 721

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+K++ND L
Sbjct: 594 FLKEVNDTL 602
>NP_001273595
          Length = 749

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+K++ND L
Sbjct: 594 FLKEVNDTL 602
>NP_001273594
          Length = 809

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+K++ND L
Sbjct: 594 FLKEVNDTL 602
>NP_001129406
          Length = 779

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+K++ND L
Sbjct: 594 FLKEVNDTL 602
>NP_001129407
          Length = 781

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+K++ND L
Sbjct: 594 FLKEVNDTL 602
>NP_006466
          Length = 836

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+K++ND L
Sbjct: 594 FLKEVNDTL 602
>NP_001129408
          Length = 751

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+K++ND L
Sbjct: 594 FLKEVNDTL 602
>NP_003904
          Length = 1007

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FMKQMNDA 8
           F+K++NDA
Sbjct: 735 FLKKLNDA 742
>XP_005266289
          Length = 806

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+K++ND L
Sbjct: 594 FLKEVNDTL 602
>XP_005266288
          Length = 808

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+K++ND L
Sbjct: 594 FLKEVNDTL 602
>XP_006715301
          Length = 867

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FMKQMNDA 8
           F+K++NDA
Sbjct: 735 FLKKLNDA 742
>XP_006710357
          Length = 475

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FMKQMNDA 8
           ++K+MNDA
Sbjct: 153 YVKEMNDA 160
>XP_005270425
          Length = 475

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FMKQMNDA 8
           ++K+MNDA
Sbjct: 153 YVKEMNDA 160
>XP_005270424
          Length = 475

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FMKQMNDA 8
           ++K+MNDA
Sbjct: 153 YVKEMNDA 160
>NP_001099000
          Length = 475

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FMKQMNDA 8
           ++K+MNDA
Sbjct: 153 YVKEMNDA 160
>NP_006358
          Length = 475

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FMKQMNDA 8
           ++K+MNDA
Sbjct: 153 YVKEMNDA 160
>NP_006357
          Length = 477

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FMKQMNDA 8
           ++K+MNDA
Sbjct: 155 YVKEMNDA 162
>NP_009123
          Length = 1047

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FMKQMNDAL 9
           FMK  ND L
Sbjct: 146 FMKSWNDCL 154
>NP_001191
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FMKQMNDAL 9
           F +QM DAL
Sbjct: 153 FREQMQDAL 161
>NP_001005743
          Length = 651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>NP_003735
          Length = 640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 199 MKQMQDA 205
>NP_001005745
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 199 MKQMQDA 205
>NP_001005744
          Length = 603

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>NP_056453
          Length = 797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+KQ+N +L
Sbjct: 613 FLKQINSSL 621
>NP_955400
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FMKQMNDAL 9
           F+KQ+N +L
Sbjct: 605 FLKQINSSL 613
>XP_006720359
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 199 MKQMQDA 205
>XP_006720358
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 199 MKQMQDA 205
>XP_006720357
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_006720356
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_006720355
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 199 MKQMQDA 205
>XP_006720354
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 199 MKQMQDA 205
>XP_006720353
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_006720352
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_006720351
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_006720350
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 199 MKQMQDA 205
>XP_006720349
          Length = 600

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_006720348
          Length = 603

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_005268203
          Length = 603

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_005268202
          Length = 637

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 199 MKQMQDA 205
>XP_005268201
          Length = 640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 199 MKQMQDA 205
>XP_006720347
          Length = 648

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_005268200
          Length = 651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_006720346
          Length = 651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>XP_005268199
          Length = 651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MKQMNDA 8
           MKQM DA
Sbjct: 210 MKQMQDA 216
>NP_001244
          Length = 802

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   MKQMND 7
           MKQ+ND
Sbjct: 732 MKQLND 737
>NP_660215
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KQMNDAL 9
           KQM DAL
Sbjct: 148 KQMQDAL 154
>NP_733936
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KQMNDAL 9
           KQ+NDA+
Sbjct: 407 KQVNDAV 413
>NP_001071
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KQMNDAL 9
           KQ+NDA+
Sbjct: 394 KQVNDAV 400
>NP_115287
          Length = 224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MKQMNDAL 9
           +KQMN+ L
Sbjct: 191 LKQMNEQL 198
>NP_000615
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   MKQMND 7
           MKQ+ND
Sbjct: 169 MKQIND 174
>NP_653277
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQMNDAL 9
           KQ+ND L
Sbjct: 153 KQLNDTL 159
>NP_653248
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  FMKQMND 7
          FMK +ND
Sbjct: 64 FMKGLND 70
>NP_001036090
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  FMKQMND 7
          FMK +ND
Sbjct: 64 FMKGLND 70
>NP_066305
          Length = 291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   FMKQMNDAL 9
           F K +ND++
Sbjct: 248 FQKSLNDSI 256
>XP_006714508
          Length = 199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  FMKQMND 7
          FMK +ND
Sbjct: 81 FMKGLND 87
>XP_006714507
          Length = 225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  FMKQMND 7
          FMK +ND
Sbjct: 81 FMKGLND 87
>XP_005245262
          Length = 891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MKQMNDAL 9
           +KQMN+ L
Sbjct: 858 LKQMNEQL 865
>XP_005245259
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MKQMNDAL 9
           +KQMN+ L
Sbjct: 965 LKQMNEQL 972
>XP_005245257
          Length = 1058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    MKQMNDAL 9
            +KQMN+ L
Sbjct: 1025 LKQMNEQL 1032
>XP_005245256
          Length = 1059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    MKQMNDAL 9
            +KQMN+ L
Sbjct: 1026 LKQMNEQL 1033
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.133    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 422,806
Number of extensions: 883
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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