Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           20     509
NP_000242                                                              20     509
XP_005264389                                                           20     509
NP_009098                                                              17    4312
NP_008853                                                              16    7355
NP_001075145                                                           16    7355
NP_001075146                                                           16    7355
XP_006712742                                                           16    7355
NP_002968                                                              15    9605
NP_004527                                                              15    9605
NP_660333                                                              15    9605
NP_075043                                                              15    9605
NP_056346                                                              15    9605
NP_001273506                                                           15    9605
XP_006725522                                                           15    9605
XP_006725521                                                           15    9605
XP_006725519                                                           15    9605
XP_006725518                                                           15    9605
XP_006725517                                                           15    9605
XP_006725516                                                           15    9605
XP_005276859                                                           15    9605
XP_005276858                                                           15    9605
XP_006726285                                                           15    9605
XP_006726284                                                           15    9605
XP_006726283                                                           15    9605
XP_006726282                                                           15    9605
XP_005273954                                                           15    9605
XP_006718558                                                           15    9605
XP_005273953                                                           15    9605
XP_005273952                                                           15    9605
XP_005273950                                                           15    9605
XP_005248581                                                           15    9605
XP_006714693                                                           15    9605
XP_006714692                                                           15    9605
XP_006714691                                                           15    9605
XP_006714690                                                           15    9605
XP_006714689                                                           15    9605
XP_005248194                                                           15    9605
XP_005246814                                                           15    9605
NP_057339                                                              15    9605
NP_690862                                                              15    9605



>NP_001245210
          Length = 868

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   FMAEMLET 8
           FMAEMLET
Sbjct: 659 FMAEMLET 666





>NP_000242
          Length = 934

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   FMAEMLET 8
           FMAEMLET
Sbjct: 725 FMAEMLET 732





>XP_005264389
          Length = 921

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   FMAEMLET 8
           FMAEMLET
Sbjct: 725 FMAEMLET 732





>NP_009098
          Length = 1325

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AEMLETT 9
           AEM+ETT
Sbjct: 283 AEMIETT 289





>NP_008853
          Length = 2000

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AEM+E
Sbjct: 1605 FLAEMIE 1611





>NP_001075145
          Length = 1951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AEM+E
Sbjct: 1556 FLAEMIE 1562





>NP_001075146
          Length = 1951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AEM+E
Sbjct: 1556 FLAEMIE 1562





>XP_006712742
          Length = 2000

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AEM+E
Sbjct: 1605 FLAEMIE 1611





>NP_002968
          Length = 1977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    FMAEMLET 8
            F+A+++ET
Sbjct: 1583 FLADLIET 1590





>NP_004527
          Length = 1403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>NP_660333
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMAEMLE 7
           F+AEM+E
Sbjct: 462 FVAEMIE 468





>NP_075043
          Length = 1241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 202 LCELLETT 209





>NP_056346
          Length = 1963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AE+LE
Sbjct: 1282 FLAELLE 1288





>NP_001273506
          Length = 2353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AE+LE
Sbjct: 1282 FLAELLE 1288





>XP_006725522
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_006725521
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_006725519
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 100 LCELLETT 107





>XP_006725518
          Length = 1219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 180 LCELLETT 187





>XP_006725517
          Length = 1348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_006725516
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_005276859
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_005276858
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_006726285
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 100 LCELLETT 107





>XP_006726284
          Length = 1219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 180 LCELLETT 187





>XP_006726283
          Length = 1348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_006726282
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_005273954
          Length = 1676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AE+LE
Sbjct: 1282 FLAELLE 1288





>XP_006718558
          Length = 1841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMAEMLE 7
           F+AE+LE
Sbjct: 769 FLAELLE 775





>XP_005273953
          Length = 2171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AE+LE
Sbjct: 1099 FLAELLE 1105





>XP_005273952
          Length = 2245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AE+LE
Sbjct: 1173 FLAELLE 1179





>XP_005273950
          Length = 2354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FMAEMLE 7
            F+AE+LE
Sbjct: 1282 FLAELLE 1288





>XP_005248581
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_006714693
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_006714692
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 100 LCELLETT 107





>XP_006714691
          Length = 1219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 180 LCELLETT 187





>XP_006714690
          Length = 1348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_006714689
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAEMLETT 9
           + E+LETT
Sbjct: 364 LCELLETT 371





>XP_005248194
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMAEMLE 7
           F+AEM+E
Sbjct: 462 FVAEMIE 468





>XP_005246814
          Length = 1988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    FMAEMLET 8
            F+A+++ET
Sbjct: 1594 FLADLIET 1601





>NP_057339
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FMAEMLE 7
           FMAEM++
Sbjct: 250 FMAEMVD 256





>NP_690862
          Length = 166

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FMAEMLET 8
           FM E+LE+
Sbjct: 152 FMTELLES 159





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.124    0.312 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 356,842
Number of extensions: 494
Number of successful extensions: 41
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 41
Number of HSP's successfully gapped: 41
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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