Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_065737                                                              17    4312
XP_005255211                                                           17    4312
NP_001120920                                                           17    4312
NP_000654                                                              17    4312
NP_001193727                                                           16    5631
NP_001193725                                                           16    5631
NP_001193726                                                           16    5631
NP_001193728                                                           16    5631
NP_872271                                                              16    5631
NP_872270                                                              16    5631
NP_002645                                                              16    5631
NP_722523                                                              16    5631
NP_065201                                                              16    5631
NP_056382                                                              16    5631
XP_005254502                                                           16    5631
XP_005254500                                                           16    5631
XP_006720633                                                           16    5631
XP_005254096                                                           16    5631
XP_005254095                                                           16    5631
XP_005248797                                                           16    5631
XP_005248796                                                           16    5631
XP_005248795                                                           16    5631
NP_001002758                                                           16    7355
NP_060009                                                              16    7355
NP_004667                                                              16    7355
XP_006721125                                                           16    7355
XP_003120383                                                           16    7355
NP_443137                                                              15    9605
NP_056036                                                              15    9605
NP_036430                                                              15    9605
NP_065768                                                              15    9605
NP_115827                                                              15    9605
NP_940931                                                              15    9605
XP_006724654                                                           15    9605
XP_006724653                                                           15    9605
XP_006721943                                                           15    9605
XP_006721942                                                           15    9605
XP_006721370                                                           15    9605
XP_006721369                                                           15    9605
XP_006721368                                                           15    9605
XP_006721367                                                           15    9605
XP_006721366                                                           15    9605
XP_006721365                                                           15    9605
XP_006717799                                                           15    9605
XP_006717798                                                           15    9605
XP_005266116                                                           15    9605
XP_005246323                                                           15    9605
XP_005246322                                                           15    9605
XP_006712291                                                           15    9605
XP_005246320                                                           15    9605
NP_001155971                                                           15    9605
NP_060918                                                              15    9605
>NP_065737
          Length = 500

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EVQ G
Sbjct: 323 FLVDEVQTG 331
>XP_005255211
          Length = 518

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EVQ G
Sbjct: 341 FLVDEVQTG 349
>NP_001120920
          Length = 500

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EVQ G
Sbjct: 323 FLVDEVQTG 331
>NP_000654
          Length = 500

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EVQ G
Sbjct: 323 FLVDEVQTG 331
>NP_001193727
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 177 FLVTEVENG 185
>NP_001193725
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 266 FLVTEVENG 274
>NP_001193726
          Length = 457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 118 FLVTEVENG 126
>NP_001193728
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 197 FLVTEVENG 205
>NP_872271
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 192 FLVTEVENG 200
>NP_872270
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 192 FLVTEVENG 200
>NP_002645
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 192 FLVTEVENG 200
>NP_722523
          Length = 946

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FLVREVQR 8
           F+V E+QR
Sbjct: 414 FIVEEIQR 421
>NP_065201
          Length = 893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FLVREVQR 8
           F+V E+QR
Sbjct: 370 FIVEEIQR 377
>NP_056382
          Length = 958

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVREVQRG 9
           L+RE+Q G
Sbjct: 492 LIREIQSG 499
>XP_005254502
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 192 FLVTEVENG 200
>XP_005254500
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 252 FLVTEVENG 260
>XP_006720633
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FLVREVQRG 9
           FLV EV+ G
Sbjct: 266 FLVTEVENG 274
>XP_005254096
          Length = 958

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVREVQRG 9
           L+RE+Q G
Sbjct: 492 LIREIQSG 499
>XP_005254095
          Length = 958

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVREVQRG 9
           L+RE+Q G
Sbjct: 492 LIREIQSG 499
>XP_005248797
          Length = 902

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FLVREVQR 8
           F+V E+QR
Sbjct: 370 FIVEEIQR 377
>XP_005248796
          Length = 937

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FLVREVQR 8
           F+V E+QR
Sbjct: 414 FIVEEIQR 421
>XP_005248795
          Length = 945

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FLVREVQR 8
           F+V E+QR
Sbjct: 413 FIVEEIQR 420
>NP_001002758
          Length = 147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FLVREVQRG 9
           FL+R ++RG
Sbjct: 122 FLLRTLERG 130
>NP_060009
          Length = 4116

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FLVREVQRG 9
            FL+ ++Q+G
Sbjct: 1151 FLLEDIQKG 1159
>NP_004667
          Length = 147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FLVREVQRG 9
           FL+R ++RG
Sbjct: 122 FLLRTLERG 130
>XP_006721125
          Length = 4070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FLVREVQRG 9
            FL+ ++Q+G
Sbjct: 1105 FLLEDIQKG 1113
>XP_003120383
          Length = 147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FLVREVQRG 9
           FL+R ++RG
Sbjct: 122 FLLRTLERG 130
>NP_443137
          Length = 1092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VREVQRG 9
           V+E+QRG
Sbjct: 903 VKELQRG 909
>NP_056036
          Length = 1577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FLVREVQR 8
           FL++ VQR
Sbjct: 918 FLIKPVQR 925
>NP_036430
          Length = 1119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVREVQRG 9
           L+REV+ G
Sbjct: 950 LIREVEMG 957
>NP_065768
          Length = 1493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LVREVQRG 9
            ++RE QRG
Sbjct: 1327 VLREAQRG 1334
>NP_115827
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LVREVQRG 9
           L+RE++RG
Sbjct: 249 LMRELRRG 256
>NP_940931
          Length = 1503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    VREVQR 8
            VREVQR
Sbjct: 1317 VREVQR 1322
>XP_006724654
          Length = 1335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LVREVQRG 9
            ++RE QRG
Sbjct: 1169 VLREAQRG 1176
>XP_006724653
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LVREVQRG 9
            ++RE QRG
Sbjct: 1211 VLREAQRG 1218
>XP_006721943
          Length = 1456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    VREVQR 8
            VREVQR
Sbjct: 1317 VREVQR 1322
>XP_006721942
          Length = 1503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    VREVQR 8
            VREVQR
Sbjct: 1317 VREVQR 1322
>XP_006721370
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LVREVQRG 9
           L+RE++RG
Sbjct: 249 LMRELRRG 256
>XP_006721369
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LVREVQRG 9
           L+RE++RG
Sbjct: 249 LMRELRRG 256
>XP_006721368
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LVREVQRG 9
           L+RE++RG
Sbjct: 249 LMRELRRG 256
>XP_006721367
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LVREVQRG 9
           L+RE++RG
Sbjct: 249 LMRELRRG 256
>XP_006721366
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LVREVQRG 9
           L+RE++RG
Sbjct: 164 LMRELRRG 171
>XP_006721365
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LVREVQRG 9
           L+RE++RG
Sbjct: 164 LMRELRRG 171
>XP_006717799
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FLVREVQR 8
           FL++ VQR
Sbjct: 918 FLIKPVQR 925
>XP_006717798
          Length = 1534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FLVREVQR 8
           FL++ VQR
Sbjct: 918 FLIKPVQR 925
>XP_005266116
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVREVQRG 9
           L+RE +RG
Sbjct: 468 LIREYRRG 475
>XP_005246323
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VREVQRG 9
           V+E+QRG
Sbjct: 880 VKELQRG 886
>XP_005246322
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VREVQRG 9
           V+E+QRG
Sbjct: 903 VKELQRG 909
>XP_006712291
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VREVQRG 9
           V+E+QRG
Sbjct: 903 VKELQRG 909
>XP_005246320
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VREVQRG 9
           V+E+QRG
Sbjct: 903 VKELQRG 909
>NP_001155971
          Length = 1236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LVREVQRG 9
            L+REV+ G
Sbjct: 1067 LIREVEMG 1074
>NP_060918
          Length = 1230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LVREVQRG 9
            L+REV+ G
Sbjct: 1062 LIREVEMG 1069
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.154    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 473,628
Number of extensions: 875
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package