Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_005255877                                                           17    3301
XP_005255876                                                           17    3301
XP_005255874                                                           17    3301
XP_006721218                                                           17    3301
XP_005255872                                                           17    3301
NP_710155                                                              17    3301
NP_055935                                                              17    4312
NP_004381                                                              17    4312
NP_065856                                                              17    4312
XP_006722575                                                           17    4312
NP_149055                                                              16    5631
NP_689413                                                              16    5631
NP_055241                                                              16    5631
NP_001269383                                                           16    5631
NP_775922                                                              16    5631
NP_001276881                                                           16    5631
NP_001276880                                                           16    5631
NP_001008401                                                           16    5631
XP_005246791                                                           16    5631
XP_005246789                                                           16    5631
NP_055928                                                              16    7355
NP_733751                                                              16    7355
NP_689668                                                              16    7355
NP_001120914                                                           16    7355
NP_612201                                                              16    7355
NP_525124                                                              16    7355
NP_001077422                                                           16    7355
NP_001258573                                                           16    7355
NP_001258572                                                           16    7355
NP_002069                                                              16    7355
NP_071348                                                              16    7355
NP_001166184                                                           16    7355
XP_006721797                                                           16    7355
XP_006721796                                                           16    7355
XP_005256618                                                           16    7355
XP_005256617                                                           16    7355
XP_006720464                                                           16    7355
XP_006716241                                                           16    7355
XP_005250769                                                           16    7355
XP_005250768                                                           16    7355
XP_005250767                                                           16    7355
XP_006716142                                                           16    7355
XP_005250088                                                           16    7355
XP_006716141                                                           16    7355
XP_005250085                                                           16    7355
XP_006716140                                                           16    7355
XP_005250084                                                           16    7355
XP_005250083                                                           16    7355
XP_005250082                                                           16    7355
XP_005265132                                                           16    7355
XP_005265131                                                           16    7355
XP_006713173                                                           16    7355
XP_005265130                                                           16    7355
XP_005265129                                                           16    7355
XP_005265128                                                           16    7355
XP_005265127                                                           16    7355
XP_005265126                                                           16    7355
XP_006712131                                                           16    7355
XP_006712130                                                           16    7355
XP_006712129                                                           16    7355
XP_006712128                                                           16    7355
XP_006712127                                                           16    7355
XP_006712126                                                           16    7355
XP_006712125                                                           16    7355
XP_006712124                                                           16    7355
NP_001139017                                                           16    7355
NP_001120913                                                           16    7355
NP_853514                                                              15    9605
NP_001012999                                                           15    9605
XP_006715469                                                           15    9605
XP_005266931                                                           15    9605
>XP_005255877
          Length = 352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FKSLVSSHR 9
           FKSL+ SH+
Sbjct: 140 FKSLLISHK 148
>XP_005255876
          Length = 352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FKSLVSSHR 9
           FKSL+ SH+
Sbjct: 140 FKSLLISHK 148
>XP_005255874
          Length = 407

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FKSLVSSHR 9
           FKSL+ SH+
Sbjct: 195 FKSLLISHK 203
>XP_006721218
          Length = 407

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FKSLVSSHR 9
           FKSL+ SH+
Sbjct: 195 FKSLLISHK 203
>XP_005255872
          Length = 430

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FKSLVSSHR 9
           FKSL+ SH+
Sbjct: 218 FKSLLISHK 226
>NP_710155
          Length = 407

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FKSLVSSHR 9
           FKSL+ SH+
Sbjct: 195 FKSLLISHK 203
>NP_055935
          Length = 4169

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FKSLVSSHR 9
            FKSL  SH+
Sbjct: 3680 FKSLEKSHK 3688
>NP_004381
          Length = 335

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FKSLVSSHR 9
          FKS +S HR
Sbjct: 35 FKSWMSKHR 43
>NP_065856
          Length = 628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FKSLVSSH 8
          F+SL SSH
Sbjct: 58 FRSLFSSH 65
>XP_006722575
          Length = 672

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FKSLVSSH 8
           F+SL SSH
Sbjct: 102 FRSLFSSH 109
>NP_149055
          Length = 637

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FKSLVSSH 8
           FK+L+S+H
Sbjct: 119 FKALLSAH 126
>NP_689413
          Length = 404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FKSLVSSH 8
           FK  VSSH
Sbjct: 136 FKKTVSSH 143
>NP_055241
          Length = 404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FKSLVSSH 8
           FK  VSSH
Sbjct: 136 FKKTVSSH 143
>NP_001269383
          Length = 299

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  FKSLVSSH 8
          FK  VSSH
Sbjct: 31 FKKTVSSH 38
>NP_775922
          Length = 6996

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FKSLVSSHR 9
            +KSL+  HR
Sbjct: 5125 YKSLIQIHR 5133
>NP_001276881
          Length = 746

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FKS++  HR
Sbjct: 309 FKSILERHR 317
>NP_001276880
          Length = 746

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FKS++  HR
Sbjct: 309 FKSILERHR 317
>NP_001008401
          Length = 746

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FKS++  HR
Sbjct: 309 FKSILERHR 317
>XP_005246791
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FKSLVSSH 8
           FK+L+S+H
Sbjct: 119 FKALLSAH 126
>XP_005246789
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FKSLVSSH 8
           FK+L+S+H
Sbjct: 119 FKALLSAH 126
>NP_055928
          Length = 2961

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  KSLVSSHR 9
          +SLVS HR
Sbjct: 70 ESLVSRHR 77
>NP_733751
          Length = 4911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LVSSHR 9
            LVSSHR
Sbjct: 4126 LVSSHR 4131
>NP_689668
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FKSLVSSHR 9
           FKSL +S+R
Sbjct: 465 FKSLQTSYR 473
>NP_001120914
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FKSLVSSH 8
           FK+L+S H
Sbjct: 316 FKALISIH 323
>NP_612201
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FKSLVSSH 8
          F+SL+ SH
Sbjct: 59 FRSLLESH 66
>NP_525124
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FKSLVSSH 8
           FK+L+S H
Sbjct: 316 FKALISIH 323
>NP_001077422
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>NP_001258573
          Length = 894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>NP_001258572
          Length = 937

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>NP_002069
          Length = 2230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1185 FQSLKSSH 1192
>NP_071348
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>NP_001166184
          Length = 2243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1207 FQSLKSSH 1214
>XP_006721797
          Length = 362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FKSLVSSH 8
          F+SL+ SH
Sbjct: 17 FRSLLESH 24
>XP_006721796
          Length = 396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FKSLVSSH 8
          F+SL+ SH
Sbjct: 51 FRSLLESH 58
>XP_005256618
          Length = 2962

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  KSLVSSHR 9
          +SLVS HR
Sbjct: 70 ESLVSRHR 77
>XP_005256617
          Length = 2966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  KSLVSSHR 9
          +SLVS HR
Sbjct: 70 ESLVSRHR 77
>XP_006720464
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FKSLVSSHR 9
           FKSL +S+R
Sbjct: 465 FKSLQTSYR 473
>XP_006716241
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FKSLVSSH 8
           FK+L+S H
Sbjct: 316 FKALISIH 323
>XP_005250769
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FKSLVSSH 8
           FK+L+S H
Sbjct: 316 FKALISIH 323
>XP_005250768
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FKSLVSSH 8
           FK+L+S H
Sbjct: 316 FKALISIH 323
>XP_005250767
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FKSLVSSH 8
           FK+L+S H
Sbjct: 316 FKALISIH 323
>XP_006716142
          Length = 4927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LVSSHR 9
            LVSSHR
Sbjct: 4142 LVSSHR 4147
>XP_005250088
          Length = 4928

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LVSSHR 9
            LVSSHR
Sbjct: 4143 LVSSHR 4148
>XP_006716141
          Length = 4959

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LVSSHR 9
            LVSSHR
Sbjct: 4174 LVSSHR 4179
>XP_005250085
          Length = 4979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LVSSHR 9
            LVSSHR
Sbjct: 4198 LVSSHR 4203
>XP_006716140
          Length = 4982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LVSSHR 9
            LVSSHR
Sbjct: 4197 LVSSHR 4202
>XP_005250084
          Length = 4982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LVSSHR 9
            LVSSHR
Sbjct: 4197 LVSSHR 4202
>XP_005250083
          Length = 4982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LVSSHR 9
            LVSSHR
Sbjct: 4197 LVSSHR 4202
>XP_005250082
          Length = 4983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LVSSHR 9
            LVSSHR
Sbjct: 4198 LVSSHR 4203
>XP_005265132
          Length = 2214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1169 FQSLKSSH 1176
>XP_005265131
          Length = 2245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1207 FQSLKSSH 1214
>XP_006713173
          Length = 2250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1205 FQSLKSSH 1212
>XP_005265130
          Length = 2252

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1207 FQSLKSSH 1214
>XP_005265129
          Length = 2269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1224 FQSLKSSH 1231
>XP_005265128
          Length = 2278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1240 FQSLKSSH 1247
>XP_005265127
          Length = 2283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1240 FQSLKSSH 1247
>XP_005265126
          Length = 2285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FKSLVSSH 8
            F+SL SSH
Sbjct: 1240 FQSLKSSH 1247
>XP_006712131
          Length = 1453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>XP_006712130
          Length = 1831

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>XP_006712129
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>XP_006712128
          Length = 1879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>XP_006712127
          Length = 1909

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>XP_006712126
          Length = 1913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 375 FKNLLQMHR 383
>XP_006712125
          Length = 1952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>XP_006712124
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FK+L+  HR
Sbjct: 415 FKNLLQMHR 423
>NP_001139017
          Length = 154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLVSSHR 9
           SLV SHR
Sbjct: 101 SLVGSHR 107
>NP_001120913
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FKSLVSSH 8
           FK+L+S H
Sbjct: 316 FKALISIH 323
>NP_853514
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    SLVSSH 8
            SLVSSH
Sbjct: 1042 SLVSSH 1047
>NP_001012999
          Length = 967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FKSL  S+R
Sbjct: 397 FKSLQKSYR 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FKSLVSSHR 9
           FKSL  S+R
Sbjct: 554 FKSLQKSYR 562
>XP_006715469
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SLVSSHR 9
          SL+SSH+
Sbjct: 71 SLISSHQ 77
>XP_005266931
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLVSSHR 9
           SL+SSH+
Sbjct: 119 SLISSHQ 125
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.125    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 477,564
Number of extensions: 1107
Number of successful extensions: 72
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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