Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245200                                                           19     665
NP_000240                                                              19     665
XP_005265218                                                           19     665
XP_006724177                                                           17    3301
NP_000762                                                              16    5631
NP_056496                                                              16    7355
XP_005256667                                                           16    7355
XP_005256666                                                           16    7355
XP_005256665                                                           16    7355
XP_005256664                                                           16    7355
XP_005256662                                                           16    7355
NP_001073991                                                           15    9605
NP_892006                                                              15    9605
NP_149062                                                              15    9605
NP_056327                                                              15    9605
NP_056140                                                              15    9605
XP_006717169                                                           15    9605
XP_006715488                                                           15    9605
XP_006715487                                                           15    9605
XP_006715486                                                           15    9605
XP_006715485                                                           15    9605
XP_006715484                                                           15    9605
XP_006715483                                                           15    9605
XP_006715482                                                           15    9605
XP_006715481                                                           15    9605
XP_006715480                                                           15    9605
XP_006715479                                                           15    9605
XP_006715478                                                           15    9605
XP_006715477                                                           15    9605
XP_006715476                                                           15    9605
XP_006715475                                                           15    9605
XP_006715474                                                           15    9605
XP_006715473                                                           15    9605
XP_006715472                                                           15    9605
XP_006715471                                                           15    9605
XP_006715470                                                           15    9605
XP_005248236                                                           15    9605
XP_005248234                                                           15    9605
XP_006713163                                                           15    9605
NP_001001676                                                           15    9605
>NP_001245200
          Length = 687

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FITSKLQSF 9
          F TSKLQSF
Sbjct: 80 FTTSKLQSF 88
>NP_000240
          Length = 756

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FITSKLQSF 9
          F TSKLQSF
Sbjct: 80 FTTSKLQSF 88
>XP_005265218
          Length = 687

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FITSKLQSF 9
          F TSKLQSF
Sbjct: 80 FTTSKLQSF 88
>XP_006724177
          Length = 383

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  FITSKLQSF 9
          F+TS+++SF
Sbjct: 42 FLTSRIRSF 50
>NP_000762
          Length = 490

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FITSKLQSF 9
           F+TS LQ+F
Sbjct: 448 FLTSILQNF 456
>NP_056496
          Length = 204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSKLQSF 9
           TSKLQ F
Sbjct: 127 TSKLQKF 133
>XP_005256667
          Length = 142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSKLQSF 9
           TSKLQ F
Sbjct: 127 TSKLQKF 133
>XP_005256666
          Length = 153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSKLQSF 9
           TSKLQ F
Sbjct: 127 TSKLQKF 133
>XP_005256665
          Length = 155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSKLQSF 9
           TSKLQ F
Sbjct: 127 TSKLQKF 133
>XP_005256664
          Length = 161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSKLQSF 9
           TSKLQ F
Sbjct: 127 TSKLQKF 133
>XP_005256662
          Length = 186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSKLQSF 9
           TSKLQ F
Sbjct: 127 TSKLQKF 133
>NP_001073991
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FITSKLQS 8
           F+T KLQ+
Sbjct: 449 FLTDKLQA 456
>NP_892006
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7449 SKLQSF 7454
>NP_149062
          Length = 8749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7378 SKLQSF 7383
>NP_056327
          Length = 4265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FITSKLQSF 9
            F+T  LQ+F
Sbjct: 4123 FLTGTLQNF 4131
>NP_056140
          Length = 2266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FITSKLQSF 9
            ++TS LQ F
Sbjct: 1151 YLTSALQDF 1159
>XP_006717169
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FITSKLQSF 9
           FIT  LQ+F
Sbjct: 119 FITFHLQNF 127
>XP_006715488
          Length = 8721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7461 SKLQSF 7466
>XP_006715487
          Length = 8744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7461 SKLQSF 7466
>XP_006715486
          Length = 8758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7461 SKLQSF 7466
>XP_006715485
          Length = 8793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7408 SKLQSF 7413
>XP_006715484
          Length = 8794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7409 SKLQSF 7414
>XP_006715483
          Length = 8795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7410 SKLQSF 7415
>XP_006715482
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7449 SKLQSF 7454
>XP_006715481
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7414 SKLQSF 7419
>XP_006715480
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7414 SKLQSF 7419
>XP_006715479
          Length = 8804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7456 SKLQSF 7461
>XP_006715478
          Length = 8809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7461 SKLQSF 7466
>XP_006715477
          Length = 8822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7437 SKLQSF 7442
>XP_006715476
          Length = 8823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7461 SKLQSF 7466
>XP_006715475
          Length = 8827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7456 SKLQSF 7461
>XP_006715474
          Length = 8829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7444 SKLQSF 7449
>XP_006715473
          Length = 8832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7461 SKLQSF 7466
>XP_006715472
          Length = 8839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7454 SKLQSF 7459
>XP_006715471
          Length = 8842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7457 SKLQSF 7462
>XP_006715470
          Length = 8846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SKLQSF 9
            SKLQSF
Sbjct: 7461 SKLQSF 7466
>XP_005248236
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FITSKLQS 8
           F+T KLQ+
Sbjct: 449 FLTDKLQA 456
>XP_005248234
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FITSKLQS 8
           F+T KLQ+
Sbjct: 449 FLTDKLQA 456
>XP_006713163
          Length = 4265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FITSKLQSF 9
            F+T  LQ+F
Sbjct: 4123 FLTGTLQNF 4131
>NP_001001676
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FITSKLQSF 9
           FIT  LQ+F
Sbjct: 119 FITFHLQNF 127
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.137    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 319,036
Number of extensions: 406
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package