Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1482
NP_001138390                                                           18    1482
NP_001138386                                                           18    1482
NP_001138387                                                           18    1482
NP_000132                                                              18    1482
NP_075259                                                              18    1482
NP_001138388                                                           18    1482
NP_001138391                                                           18    1482
NP_001138385                                                           18    1482
NP_075418                                                              18    1482
XP_006717776                                                           18    1482
XP_006717775                                                           18    1482
XP_006717774                                                           18    1482
XP_006717773                                                           18    1482
XP_006717772                                                           18    1482
XP_006717771                                                           18    1482
NP_001004726                                                           16    5631
NP_062815                                                              16    7355
NP_001254539                                                           16    7355
NP_722561                                                              16    7355
NP_001254538                                                           16    7355
NP_001254540                                                           16    7355
NP_001499                                                              16    7355
XP_006711316                                                           16    7355
XP_005245114                                                           16    7355
XP_005245113                                                           16    7355
XP_006711315                                                           16    7355
XP_005245112                                                           16    7355
XP_006711314                                                           16    7355
NP_795365                                                              16    7355
>NP_001138389
          Length = 705

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>NP_001138390
          Length = 704

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>NP_001138386
          Length = 709

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>NP_001138387
          Length = 707

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>NP_000132
          Length = 821

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>NP_075259
          Length = 822

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>NP_001138388
          Length = 706

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>NP_001138391
          Length = 680

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>NP_001138385
          Length = 769

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>NP_075418
          Length = 732

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 7  FICLVVVTM 15
>XP_006717776
          Length = 806

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 26 FICLVVVTM 34
>XP_006717775
          Length = 726

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 26 FICLVVVTM 34
>XP_006717774
          Length = 752

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 26 FICLVVVTM 34
>XP_006717773
          Length = 807

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 26 FICLVVVTM 34
>XP_006717772
          Length = 838

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 26 FICLVVVTM 34
>XP_006717771
          Length = 839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FISLVVVTM 9
          FI LVVVTM
Sbjct: 26 FICLVVVTM 34
>NP_001004726
          Length = 305

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FISLVVVT 8
           FISL+++T
Sbjct: 192 FISLLIIT 199
>NP_062815
          Length = 729

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FISLVVVTM 9
           + SLV+VTM
Sbjct: 432 YASLVLVTM 440
>NP_001254539
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 31 FIAIIVITI 39
>NP_722561
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 31 FIAIIVITI 39
>NP_001254538
          Length = 549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 51 FIAIIVITI 59
>NP_001254540
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 48 FIAIIVITI 56
>NP_001499
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FISLVVVTM 9
           F+ L+VVT+
Sbjct: 284 FLRLIVVTL 292
>XP_006711316
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 31 FIAIIVITI 39
>XP_005245114
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 31 FIAIIVITI 39
>XP_005245113
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 31 FIAIIVITI 39
>XP_006711315
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 31 FIAIIVITI 39
>XP_005245112
          Length = 549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 51 FIAIIVITI 59
>XP_006711314
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FISLVVVTM 9
          FI+++V+T+
Sbjct: 54 FIAIIVITI 62
>NP_795365
          Length = 309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  FISLVVVT 8
          F SLVVVT
Sbjct: 9  FSSLVVVT 16
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.350    0.151    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 238,168
Number of extensions: 283
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)

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