Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001181926                                                           20     509
NP_001014437                                                           20     509
NP_001742                                                              20     509
NP_644802                                                              20     509
XP_006725193                                                           20     509
XP_006725192                                                           20     509
XP_006718404                                                           20     509
XP_006718403                                                           20     509
NP_004739                                                              19     869
NP_001191379                                                           19     869
NP_065790                                                              19     869
NP_938008                                                              17    3301
NP_061944                                                              17    3301
NP_002159                                                              17    4312
NP_001277043                                                           17    4312
NP_001276839                                                           17    4312
NP_071379                                                              17    4312
XP_005260849                                                           17    4312
NP_942093                                                              17    4312
NP_001157790                                                           16    5631
NP_001157791                                                           16    5631
NP_055664                                                              16    5631
NP_001157789                                                           16    5631
NP_001082                                                              16    5631
NP_001259001                                                           16    5631
NP_001448                                                              16    5631
NP_036519                                                              16    5631
NP_065748                                                              16    5631
XP_005250024                                                           16    5631
XP_006715981                                                           16    5631
XP_006713130                                                           16    5631
XP_005265035                                                           16    5631
XP_005265034                                                           16    5631
NP_001108207                                                           16    7355
NP_004040                                                              16    7355
NP_003819                                                              15    9605
NP_940905                                                              15    9605
NP_001274748                                                           15    9605
NP_001274749                                                           15    9605
NP_065873                                                              15    9605
NP_663624                                                              15    9605
NP_690000                                                              15    9605
NP_002214                                                              15    9605
NP_001482                                                              15    9605
NP_940933                                                              15    9605
NP_663630                                                              15    9605
NP_001258932                                                           15    9605
NP_001184216                                                           15    9605
XP_006724919                                                           15    9605
XP_006724918                                                           15    9605
XP_005274825                                                           15    9605
XP_005274824                                                           15    9605
XP_005274823                                                           15    9605
XP_006724917                                                           15    9605
XP_005274822                                                           15    9605
XP_005274541                                                           15    9605
XP_005274540                                                           15    9605
XP_005274539                                                           15    9605
XP_006722513                                                           15    9605
XP_006722512                                                           15    9605
XP_006722510                                                           15    9605
XP_005266750                                                           15    9605
XP_005266749                                                           15    9605
XP_005266748                                                           15    9605
XP_005266747                                                           15    9605
XP_006717257                                                           15    9605
XP_006717256                                                           15    9605
XP_005249503                                                           15    9605
XP_005249056                                                           15    9605
XP_006715115                                                           15    9605
XP_006711358                                                           15    9605
XP_006711357                                                           15    9605
NP_113668                                                              15    9605
NP_694550                                                              15    9605
NP_001013372                                                           15    9605
NP_001005239                                                           15    9605
>NP_001181926
          Length = 809

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           F+NEFF+N
Sbjct: 541 FLNEFFLN 548
>NP_001014437
          Length = 831

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           F+NEFF+N
Sbjct: 541 FLNEFFLN 548
>NP_001742
          Length = 748

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           F+NEFF+N
Sbjct: 458 FLNEFFLN 465
>NP_644802
          Length = 726

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           F+NEFF+N
Sbjct: 458 FLNEFFLN 465
>XP_006725193
          Length = 738

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           F+NEFF+N
Sbjct: 448 FLNEFFLN 455
>XP_006725192
          Length = 769

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           F+NEFF+N
Sbjct: 541 FLNEFFLN 548
>XP_006718404
          Length = 738

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           F+NEFF+N
Sbjct: 448 FLNEFFLN 455
>XP_006718403
          Length = 769

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           F+NEFF+N
Sbjct: 541 FLNEFFLN 548
>NP_004739
          Length = 757

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           FIN+FF+N
Sbjct: 680 FINKFFLN 687
>NP_001191379
          Length = 807

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           FIN+FF+N
Sbjct: 680 FINKFFLN 687
>NP_065790
          Length = 757

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FINEFFMN 8
           FIN+FF+N
Sbjct: 680 FINKFFLN 687
>NP_938008
          Length = 92

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  INEFFMN 8
          ++EFFMN
Sbjct: 43 VSEFFMN 49
>NP_061944
          Length = 418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  INEFFMN 8
          ++EFFMN
Sbjct: 43 VSEFFMN 49
>NP_002159
          Length = 452

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INEFFMNT 9
           +NE F+NT
Sbjct: 427 LNEHFLNT 434
>NP_001277043
          Length = 322

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INEFFMNT 9
           +NE F+NT
Sbjct: 297 LNEHFLNT 304
>NP_001276839
          Length = 400

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INEFFMNT 9
           +NE F+NT
Sbjct: 375 LNEHFLNT 382
>NP_071379
          Length = 776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   INEFFMNT 9
           INEFF  T
Sbjct: 392 INEFFKGT 399
>XP_005260849
          Length = 587

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   INEFFMNT 9
           INEFF  T
Sbjct: 203 INEFFKGT 210
>NP_942093
          Length = 776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   INEFFMNT 9
           INEFF  T
Sbjct: 392 INEFFKGT 399
>NP_001157790
          Length = 2591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NEFFMNT 9
            +EFF+NT
Sbjct: 2392 SEFFINT 2398
>NP_001157791
          Length = 2578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NEFFMNT 9
            +EFF+NT
Sbjct: 2379 SEFFINT 2385
>NP_055664
          Length = 742

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FINEFFMNT 9
           FIN  F NT
Sbjct: 551 FINTVFYNT 559
>NP_001157789
          Length = 2633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NEFFMNT 9
            +EFF+NT
Sbjct: 2434 SEFFINT 2440
>NP_001082
          Length = 751

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   INEFFMNT 9
           +++FF+NT
Sbjct: 162 LHQFFLNT 169
>NP_001259001
          Length = 770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   INEFFMNT 9
           +++FF+NT
Sbjct: 162 LHQFFLNT 169
>NP_001448
          Length = 2602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NEFFMNT 9
            +EFF+NT
Sbjct: 2403 SEFFINT 2409
>NP_036519
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           FIN+FF
Sbjct: 629 FINDFF 634
>NP_065748
          Length = 477

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INEFFMNT 9
           INEFF+++
Sbjct: 110 INEFFIDS 117
>XP_005250024
          Length = 751

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   INEFFMNT 9
           +++FF+NT
Sbjct: 162 LHQFFLNT 169
>XP_006715981
          Length = 770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   INEFFMNT 9
           +++FF+NT
Sbjct: 162 LHQFFLNT 169
>XP_006713130
          Length = 2109

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NEFFMNT 9
            +EFF+NT
Sbjct: 1910 SEFFINT 1916
>XP_005265035
          Length = 2609

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NEFFMNT 9
            +EFF+NT
Sbjct: 2410 SEFFINT 2416
>XP_005265034
          Length = 2622

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NEFFMNT 9
            +EFF+NT
Sbjct: 2423 SEFFINT 2429
>NP_001108207
          Length = 163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F+ EF MN
Sbjct: 121 FVAEFIMN 128
>NP_004040
          Length = 175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F+ EF MN
Sbjct: 121 FVAEFIMN 128
>NP_003819
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F N FF+N
Sbjct: 572 FSNPFFVN 579
>NP_940905
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NEF+
Sbjct: 317 FLNEFY 322
>NP_001274748
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NEF+
Sbjct: 317 FLNEFY 322
>NP_001274749
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NEF+
Sbjct: 317 FLNEFY 322
>NP_065873
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NEF+
Sbjct: 389 FLNEFY 394
>NP_663624
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FINEFFMNT 9
           F N+F +NT
Sbjct: 364 FANKFELNT 372
>NP_690000
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   NEFFMN 8
           N FFMN
Sbjct: 138 NPFFMN 143
>NP_002214
          Length = 2701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2    INEFFMNT 9
            +N+FF  T
Sbjct: 2193 VNDFFQQT 2200
>NP_001482
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FINEFFMNT 9
           F N+F +NT
Sbjct: 362 FANKFELNT 370
>NP_940933
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    FINEFF 6
            F+NE+F
Sbjct: 1086 FLNEYF 1091
>NP_663630
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FINEFFMNT 9
           F N+F +NT
Sbjct: 364 FANKFELNT 372
>NP_001258932
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NEF+
Sbjct: 344 FLNEFY 349
>NP_001184216
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  FINEFFM 7
          F+NEF +
Sbjct: 23 FVNEFIL 29
>XP_006724919
          Length = 571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F N FF+N
Sbjct: 478 FSNPFFVN 485
>XP_006724918
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F N FF+N
Sbjct: 572 FSNPFFVN 579
>XP_005274825
          Length = 673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F N FF+N
Sbjct: 580 FSNPFFVN 587
>XP_005274824
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F N FF+N
Sbjct: 589 FSNPFFVN 596
>XP_005274823
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F N FF+N
Sbjct: 589 FSNPFFVN 596
>XP_006724917
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F N FF+N
Sbjct: 597 FSNPFFVN 604
>XP_005274822
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FINEFFMN 8
           F N FF+N
Sbjct: 606 FSNPFFVN 613
>XP_005274541
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   NEFFMN 8
           N FFMN
Sbjct: 138 NPFFMN 143
>XP_005274540
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   NEFFMN 8
           N FFMN
Sbjct: 138 NPFFMN 143
>XP_005274539
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   NEFFMN 8
           N FFMN
Sbjct: 138 NPFFMN 143
>XP_006722513
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NE+F
Sbjct: 726 FLNEYF 731
>XP_006722512
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NE+F
Sbjct: 780 FLNEYF 785
>XP_006722510
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NE+F
Sbjct: 993 FLNEYF 998
>XP_005266750
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    FINEFF 6
            F+NE+F
Sbjct: 1045 FLNEYF 1050
>XP_005266749
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    FINEFF 6
            F+NE+F
Sbjct: 1086 FLNEYF 1091
>XP_005266748
          Length = 1136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    FINEFF 6
            F+NE+F
Sbjct: 1086 FLNEYF 1091
>XP_005266747
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    FINEFF 6
            F+NE+F
Sbjct: 1086 FLNEYF 1091
>XP_006717257
          Length = 1083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NEF+
Sbjct: 216 FLNEFY 221
>XP_006717256
          Length = 1172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NEF+
Sbjct: 305 FLNEFY 310
>XP_005249503
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   INEFFM 7
           +N+FFM
Sbjct: 260 VNDFFM 265
>XP_005249056
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FINEFFMNT 9
           F N+F +NT
Sbjct: 287 FANKFELNT 295
>XP_006715115
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FINEFFMNT 9
           F N+F +NT
Sbjct: 364 FANKFELNT 372
>XP_006711358
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NEF+
Sbjct: 317 FLNEFY 322
>XP_006711357
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   FINEFF 6
           F+NEF+
Sbjct: 317 FLNEFY 322
>NP_113668
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   INEFFM 7
           +N+FFM
Sbjct: 364 VNDFFM 369
>NP_694550
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   INEFFM 7
           +N+FFM
Sbjct: 123 VNDFFM 128
>NP_001013372
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  FINEFFM 7
          F+NEF +
Sbjct: 23 FVNEFIL 29
>NP_001005239
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  FINEFFM 7
          F+NEF +
Sbjct: 23 FVNEFIL 29
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.344    0.150    0.466 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 504,052
Number of extensions: 1107
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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