Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              20     509
NP_001120972                                                           20     509
XP_006716052                                                           20     509
XP_006716051                                                           20     509
XP_005270452                                                           17    4312
NP_006836                                                              17    4312
NP_071935                                                              16    7355
NP_002110                                                              16    7355
NP_001265667                                                           16    7355
NP_057677                                                              16    7355
XP_006726149                                                           16    7355
XP_005275597                                                           16    7355
XP_006726059                                                           16    7355
XP_005275440                                                           16    7355
XP_006725969                                                           16    7355
XP_005275300                                                           16    7355
XP_006725878                                                           16    7355
XP_005275163                                                           16    7355
XP_006725760                                                           16    7355
XP_005275008                                                           16    7355
XP_006725546                                                           16    7355
XP_005272861                                                           16    7355
XP_005249228                                                           16    7355
XP_006715139                                                           16    7355
XP_005249104                                                           16    7355
NP_996816                                                              15    9605
NP_000598                                                              15    9605
NP_001152                                                              15    9605
NP_671702                                                              15    9605
NP_115655                                                              15    9605
NP_001231319                                                           15    9605
NP_005119                                                              15    9605
NP_067050                                                              15    9605
NP_001254747                                                           15    9605
NP_671701                                                              15    9605
XP_005261542                                                           15    9605
XP_006724131                                                           15    9605
XP_005247886                                                           15    9605
XP_006713849                                                           15    9605
NP_777592                                                              15    9605
NP_000599                                                              15    9605
NP_443085                                                              15    9605



>NP_000236
          Length = 1390

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FILVQRSNG 9
          F LVQRSNG
Sbjct: 16 FTLVQRSNG 24





>NP_001120972
          Length = 1408

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FILVQRSNG 9
          F LVQRSNG
Sbjct: 16 FTLVQRSNG 24





>XP_006716052
          Length = 1409

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FILVQRSNG 9
          F LVQRSNG
Sbjct: 35 FTLVQRSNG 43





>XP_006716051
          Length = 1427

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  FILVQRSNG 9
          F LVQRSNG
Sbjct: 35 FTLVQRSNG 43





>XP_005270452
          Length = 684

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILVQRSNG 9
          I +QRSNG
Sbjct: 17 IKIQRSNG 24





>NP_006836
          Length = 725

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILVQRSNG 9
          I +QRSNG
Sbjct: 17 IKIQRSNG 24





>NP_071935
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILVQRSNG 9
          +LVQ SNG
Sbjct: 24 VLVQFSNG 31





>NP_002110
          Length = 250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           ILV+RSN
Sbjct: 98  ILVERSN 104





>NP_001265667
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FILVQRSN 8
          F+L+QR N
Sbjct: 18 FLLLQRKN 25





>NP_057677
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FILVQRSN 8
          F+L+QR N
Sbjct: 18 FLLLQRKN 25





>XP_006726149
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  ILVQRSN 8
          ILV+RSN
Sbjct: 68 ILVERSN 74





>XP_005275597
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           ILV+RSN
Sbjct: 98  ILVERSN 104





>XP_006726059
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  ILVQRSN 8
          ILV+RSN
Sbjct: 68 ILVERSN 74





>XP_005275440
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           ILV+RSN
Sbjct: 98  ILVERSN 104





>XP_006725969
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  ILVQRSN 8
          ILV+RSN
Sbjct: 68 ILVERSN 74





>XP_005275300
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           ILV+RSN
Sbjct: 98  ILVERSN 104





>XP_006725878
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  ILVQRSN 8
          ILV+RSN
Sbjct: 68 ILVERSN 74





>XP_005275163
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           ILV+RSN
Sbjct: 98  ILVERSN 104





>XP_006725760
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  ILVQRSN 8
          ILV+RSN
Sbjct: 68 ILVERSN 74





>XP_005275008
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           ILV+RSN
Sbjct: 98  ILVERSN 104





>XP_006725546
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  ILVQRSN 8
          ILV+RSN
Sbjct: 68 ILVERSN 74





>XP_005272861
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           ILV+RSN
Sbjct: 98  ILVERSN 104





>XP_005249228
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FILVQRSN 8
          F+L+QR N
Sbjct: 18 FLLLQRKN 25





>XP_006715139
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  ILVQRSN 8
          ILV+RSN
Sbjct: 68 ILVERSN 74





>XP_005249104
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           ILV+RSN
Sbjct: 98  ILVERSN 104





>NP_996816
          Length = 5202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FILVQRSNG 9
            FI+ Q+ NG
Sbjct: 4072 FIVEQKENG 4080





>NP_000598
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FILVQRSNG 9
           ++ VQR NG
Sbjct: 96  YLNVQRENG 104





>NP_001152
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  FILVQRSNG 9
          F+L+Q S+G
Sbjct: 26 FLLLQASDG 34





>NP_671702
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  FILVQRSNG 9
          F+L+Q S+G
Sbjct: 26 FLLLQASDG 34





>NP_115655
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FILVQR 6
           FILVQR
Sbjct: 990 FILVQR 995





>NP_001231319
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  FILVQRSNG 9
          F+L+Q S+G
Sbjct: 26 FLLLQASDG 34





>NP_005119
          Length = 2298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           +LVQR+N
Sbjct: 240 VLVQRNN 246





>NP_067050
          Length = 149

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FILVQRSN 8
           FI++ RSN
Sbjct: 101 FIILDRSN 108





>NP_001254747
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FILVQRSN 8
           FI++ RSN
Sbjct: 101 FIILDRSN 108





>NP_671701
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  FILVQRSNG 9
          F+L+Q S+G
Sbjct: 26 FLLLQASDG 34





>XP_005261542
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FILVQRSN 8
          F+L +RSN
Sbjct: 82 FVLPERSN 89





>XP_006724131
          Length = 2298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILVQRSN 8
           +LVQR+N
Sbjct: 240 VLVQRNN 246





>XP_005247886
          Length = 1127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FILVQR 6
           FILVQR
Sbjct: 990 FILVQR 995





>XP_006713849
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FILVQR 6
           FILVQR
Sbjct: 941 FILVQR 946





>NP_777592
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FILVQRSN 8
           F+L +RSN
Sbjct: 268 FVLPERSN 275





>NP_000599
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FILVQRSNG 9
           ++ VQR NG
Sbjct: 96  YLNVQRENG 104





>NP_443085
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILVQRSNG 9
           ILVQ +NG
Sbjct: 451 ILVQGANG 458





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.147    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 409,449
Number of extensions: 638
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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