Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000312                                                              19     665
NP_001724                                                              17    2528
NP_004056                                                              17    2528
NP_071407                                                              17    3301
NP_542178                                                              17    3301
NP_817123                                                              17    3301
XP_006718005                                                           17    3301
XP_006718004                                                           17    3301
XP_006718003                                                           17    3301
XP_005275746                                                           17    3301
XP_003403671                                                           17    3301
XP_006710003                                                           17    3301
NP_001127925                                                           17    3301
NP_001140                                                              17    4312
NP_001191332                                                           17    4312
NP_001191333                                                           17    4312
NP_061743                                                              17    4312
NP_037472                                                              17    4312
NP_114476                                                              17    4312
XP_005269773                                                           17    4312
XP_005269772                                                           17    4312
XP_006717865                                                           17    4312
XP_006717864                                                           17    4312
XP_006717863                                                           17    4312
XP_006717862                                                           17    4312
XP_006717861                                                           17    4312
XP_006717860                                                           17    4312
XP_006717859                                                           17    4312
XP_006717858                                                           17    4312
XP_006717857                                                           17    4312
XP_006717856                                                           17    4312
XP_006717855                                                           17    4312
XP_006717854                                                           17    4312
XP_006717853                                                           17    4312
NP_001172005                                                           16    5631
NP_001172010                                                           16    5631
NP_001172004                                                           16    5631
NP_002015                                                              16    5631
NP_001172011                                                           16    5631
NP_061181                                                              16    7355
NP_001165402                                                           16    7355
NP_001165401                                                           16    7355
NP_620168                                                              16    7355
NP_817089                                                              16    7355
NP_001008781                                                           16    7355
NP_060009                                                              16    7355
NP_001171473                                                           16    7355
XP_006722720                                                           16    7355
XP_006722719                                                           16    7355
XP_006722718                                                           16    7355
XP_006722717                                                           16    7355
XP_006721125                                                           16    7355
NP_963844                                                              16    7355
NP_004360                                                              15    9605
NP_476508                                                              15    9605
NP_476507                                                              15    9605
NP_001990                                                              15    9605
NP_872298                                                              15    9605
NP_001243595                                                           15    9605
NP_001243596                                                           15    9605
NP_001243597                                                           15    9605
XP_006724435                                                           15    9605
XP_006713995                                                           15    9605
XP_006713993                                                           15    9605
XP_005246123                                                           15    9605
XP_005246122                                                           15    9605
XP_006712316                                                           15    9605
NP_003695                                                              15    9605
NP_001129244                                                           15    9605
>NP_000312
          Length = 928

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FIEAVDLDE 9
           FI AVDLDE
Sbjct: 104 FIAAVDLDE 112
>NP_001724
          Length = 705

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FIEAVDLDE 9
           + +AVDLDE
Sbjct: 137 YYQAVDLDE 145
>NP_004056
          Length = 262

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FIEAVDLDE 9
           F+EA+DL E
Sbjct: 111 FLEAIDLRE 119
>NP_071407
          Length = 3354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            I+A+DLDE
Sbjct: 1657 IQALDLDE 1664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 912 VVAIDLDE 919
>NP_542178
          Length = 235

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  FIEAVDLDE 9
          FI+A DLD+
Sbjct: 17 FIDAKDLDQ 25
>NP_817123
          Length = 1040

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IEAVDLDE 9
           ++A+DLDE
Sbjct: 290 LQAIDLDE 297
>XP_006718005
          Length = 3397

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            I+A+DLDE
Sbjct: 1700 IQALDLDE 1707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 955 VVAIDLDE 962
>XP_006718004
          Length = 3399

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            I+A+DLDE
Sbjct: 1702 IQALDLDE 1709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 957 VVAIDLDE 964
>XP_006718003
          Length = 3419

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            I+A+DLDE
Sbjct: 1722 IQALDLDE 1729

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 977 VVAIDLDE 984
>XP_005275746
          Length = 3352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            I+A+DLDE
Sbjct: 1655 IQALDLDE 1662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 910 VVAIDLDE 917
>XP_003403671
          Length = 3354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            I+A+DLDE
Sbjct: 1657 IQALDLDE 1664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 912 VVAIDLDE 919
>XP_006710003
          Length = 3374

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            I+A+DLDE
Sbjct: 1677 IQALDLDE 1684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 932 VVAIDLDE 939
>NP_001127925
          Length = 1059

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IEAVDLDE 9
           ++A+DLDE
Sbjct: 290 LQAIDLDE 297
>NP_001140
          Length = 1001

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EAVDLDE 9
           EAVD+DE
Sbjct: 808 EAVDVDE 814
>NP_001191332
          Length = 1861

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1668 EAVDVDE 1674
>NP_001191333
          Length = 1868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1675 EAVDVDE 1681
>NP_061743
          Length = 932

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 264 VHAIDLDE 271
>NP_037472
          Length = 818

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + AVDLDE
Sbjct: 264 VTAVDLDE 271
>NP_114476
          Length = 817

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 264 VHAIDLDE 271
>XP_005269773
          Length = 1867

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1674 EAVDVDE 1680
>XP_005269772
          Length = 1885

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1692 EAVDVDE 1698
>XP_006717865
          Length = 1898

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1705 EAVDVDE 1711
>XP_006717864
          Length = 1924

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1636 EAVDVDE 1642
>XP_006717863
          Length = 1972

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1684 EAVDVDE 1690
>XP_006717862
          Length = 1981

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1693 EAVDVDE 1699
>XP_006717861
          Length = 1984

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1696 EAVDVDE 1702
>XP_006717860
          Length = 1993

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 1705 EAVDVDE 1711
>XP_006717859
          Length = 2758

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 2566 EAVDVDE 2572
>XP_006717858
          Length = 2775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 2566 EAVDVDE 2572
>XP_006717857
          Length = 2794

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 2506 EAVDVDE 2512
>XP_006717856
          Length = 2833

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 2566 EAVDVDE 2572
>XP_006717855
          Length = 2837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 2566 EAVDVDE 2572
>XP_006717854
          Length = 2852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 2566 EAVDVDE 2572
>XP_006717853
          Length = 2854

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            EAVD+DE
Sbjct: 2566 EAVDVDE 2572
>NP_001172005
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 250 VTAIDLDE 257
>NP_001172010
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 250 VTAIDLDE 257
>NP_001172004
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 250 VTAIDLDE 257
>NP_002015
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 250 VTAIDLDE 257
>NP_001172011
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 250 VTAIDLDE 257
>NP_061181
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IEAVDLDE 9
          +EAV+LD+
Sbjct: 45 LEAVELDD 52
>NP_001165402
          Length = 1061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 912 VVAIDLDE 919
>NP_001165401
          Length = 1381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+DLDE
Sbjct: 912 VVAIDLDE 919
>NP_620168
          Length = 1300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FIEAVDLD 8
           ++E VD+D
Sbjct: 266 YVETVDID 273
>NP_817089
          Length = 832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AVDLDE 9
           AVDLDE
Sbjct: 189 AVDLDE 194
>NP_001008781
          Length = 4557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           + A+D+DE
Sbjct: 600 VSAIDIDE 607
>NP_060009
          Length = 4116

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FIEAVDLDE 9
            F+E V+LD+
Sbjct: 2607 FLEDVELDD 2615
>NP_001171473
          Length = 1263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FIEAVDLD 8
           ++E VD+D
Sbjct: 213 YVETVDID 220
>XP_006722720
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FIEAVDLD 8
           ++E VD+D
Sbjct: 266 YVETVDID 273
>XP_006722719
          Length = 1224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FIEAVDLD 8
           ++E VD+D
Sbjct: 180 YVETVDID 187
>XP_006722718
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FIEAVDLD 8
           ++E VD+D
Sbjct: 266 YVETVDID 273
>XP_006722717
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FIEAVDLD 8
           ++E VD+D
Sbjct: 266 YVETVDID 273
>XP_006721125
          Length = 4070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FIEAVDLDE 9
            F+E V+LD+
Sbjct: 2561 FLEDVELDD 2569
>NP_963844
          Length = 277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FIEAVDLD 8
           F+E +D+D
Sbjct: 191 FLEVIDVD 198
>NP_004360
          Length = 3177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    IEAVDLDE 9
            +EA D DE
Sbjct: 1898 VEAFDFDE 1905
>NP_476508
          Length = 2971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    IEAVDLDE 9
            +EA D DE
Sbjct: 1692 VEAFDFDE 1699
>NP_476507
          Length = 2570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    IEAVDLDE 9
            +EA D DE
Sbjct: 1291 VEAFDFDE 1298
>NP_001990
          Length = 2912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    EAVDLDE 9
            +AVD+DE
Sbjct: 1805 KAVDIDE 1811
>NP_872298
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           IEA+ +DE
Sbjct: 145 IEAISVDE 152
>NP_001243595
          Length = 1265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            +++VD+DE
Sbjct: 1218 LDSVDMDE 1225
>NP_001243596
          Length = 1246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            +++VD+DE
Sbjct: 1199 LDSVDMDE 1206
>NP_001243597
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            +++VD+DE
Sbjct: 1177 LDSVDMDE 1184
>XP_006724435
          Length = 224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           IEA+ +DE
Sbjct: 145 IEAISVDE 152
>XP_006713995
          Length = 1448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            +++VD+DE
Sbjct: 1401 LDSVDMDE 1408
>XP_006713993
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            +++VD+DE
Sbjct: 1377 LDSVDMDE 1384
>XP_005246123
          Length = 2770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    IEAVDLDE 9
            +EA D DE
Sbjct: 1491 VEAFDFDE 1498
>XP_005246122
          Length = 2977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    IEAVDLDE 9
            +EA D DE
Sbjct: 1698 VEAFDFDE 1705
>XP_006712316
          Length = 3010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    IEAVDLDE 9
            +EA D DE
Sbjct: 1731 VEAFDFDE 1738
>NP_003695
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    IEAVDLDE 9
            +++VD+DE
Sbjct: 1177 LDSVDMDE 1184
>NP_001129244
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEAVDLDE 9
           IEA+ +DE
Sbjct: 145 IEAISVDE 152
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.147    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 478,212
Number of extensions: 1827
Number of successful extensions: 76
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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