Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003290                                                              20     390
NP_056256                                                              16    5631
XP_005245133                                                           16    5631
XP_005245132                                                           16    5631
NP_996879                                                              16    7355
NP_005116                                                              16    7355
NP_001123529                                                           16    7355
NP_001276879                                                           16    7355
NP_001123527                                                           16    7355
NP_001951                                                              16    7355
NP_001121700                                                           16    7355
NP_001123525                                                           16    7355
NP_055858                                                              16    7355
NP_001182132                                                           16    7355
NP_115754                                                              16    7355
NP_942568                                                              16    7355
NP_060440                                                              16    7355
NP_775871                                                              16    7355
XP_006725230                                                           16    7355
XP_006725138                                                           16    7355
XP_006725136                                                           16    7355
XP_006725135                                                           16    7355
XP_006725134                                                           16    7355
XP_006725133                                                           16    7355
XP_006725132                                                           16    7355
XP_006725131                                                           16    7355
XP_006725130                                                           16    7355
XP_006725128                                                           16    7355
XP_006725127                                                           16    7355
XP_006720283                                                           16    7355
XP_006720249                                                           16    7355
XP_006716588                                                           16    7355
XP_005250881                                                           16    7355
XP_005250880                                                           16    7355
XP_006716587                                                           16    7355
XP_006716586                                                           16    7355
XP_006716585                                                           16    7355
XP_006716584                                                           16    7355
XP_005250878                                                           16    7355
XP_006716582                                                           16    7355
XP_005250877                                                           16    7355
XP_006710494                                                           16    7355
XP_006710492                                                           16    7355
XP_006710491                                                           16    7355
XP_006710490                                                           16    7355
XP_006710489                                                           16    7355
NP_065869                                                              16    7355
NP_004516                                                              15    9605
NP_001177894                                                           15    9605
NP_001177893                                                           15    9605
NP_932072                                                              15    9605
NP_003444                                                              15    9605
NP_055486                                                              15    9605
NP_006175                                                              15    9605
XP_005266578                                                           15    9605
XP_005266576                                                           15    9605
XP_005266575                                                           15    9605
XP_005266577                                                           15    9605
XP_005266574                                                           15    9605
XP_005249622                                                           15    9605
XP_005249621                                                           15    9605
XP_006712591                                                           15    9605
XP_006712589                                                           15    9605
>NP_003290
          Length = 803

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FIAGSSRKE 9
           F+AGSSRKE
Sbjct: 540 FMAGSSRKE 548
>NP_056256
          Length = 750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AGSSRKE 9
           AG+SRKE
Sbjct: 94  AGASRKE 100
>XP_005245133
          Length = 751

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AGSSRKE 9
           AG+SRKE
Sbjct: 94  AGASRKE 100
>XP_005245132
          Length = 752

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AGSSRKE 9
           AG+SRKE
Sbjct: 94  AGASRKE 100
>NP_996879
          Length = 2223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    IAGSSRKE 9
            +AG +RKE
Sbjct: 2020 VAGQTRKE 2027
>NP_005116
          Length = 274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IAGSSRKE 9
           IAG  RKE
Sbjct: 259 IAGKGRKE 266
>NP_001123529
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IAGSSRKE 9
          +AG+SR+E
Sbjct: 33 VAGASRQE 40
>NP_001276879
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IAGSSRKE 9
          +AG+SR+E
Sbjct: 33 VAGASRQE 40
>NP_001123527
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IAGSSRKE 9
          +AG+SR+E
Sbjct: 33 VAGASRQE 40
>NP_001951
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IAGSSRKE 9
          +AG+SR+E
Sbjct: 33 VAGASRQE 40
>NP_001121700
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AGSSRKE 9
           AGSSRK+
Sbjct: 569 AGSSRKK 575
>NP_001123525
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>NP_055858
          Length = 1233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GSSRKE 9
          GSSRKE
Sbjct: 77 GSSRKE 82
>NP_001182132
          Length = 262

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IAGSSRKE 9
          +AG+SR+E
Sbjct: 33 VAGASRQE 40
>NP_115754
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>NP_942568
          Length = 1250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GSSRKE 9
          GSSRKE
Sbjct: 77 GSSRKE 82
>NP_060440
          Length = 1164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GSSRKE 9
          GSSRKE
Sbjct: 17 GSSRKE 22
>NP_775871
          Length = 8384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FIAGSSRKE 9
            FI+GSS  E
Sbjct: 7199 FISGSSNTE 7207
>XP_006725230
          Length = 2636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IAGSSRKE 9
           I GSSR+E
Sbjct: 207 ILGSSRRE 214
>XP_006725138
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IAGSSRKE 9
          +AG+SR+E
Sbjct: 33 VAGASRQE 40
>XP_006725136
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006725135
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006725134
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006725133
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006725132
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006725131
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006725130
          Length = 648

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 400 VAGASRQE 407
>XP_006725128
          Length = 687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 439 VAGASRQE 446
>XP_006725127
          Length = 688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 440 VAGASRQE 447
>XP_006720283
          Length = 2636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IAGSSRKE 9
           I GSSR+E
Sbjct: 207 ILGSSRRE 214
>XP_006720249
          Length = 623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GSSRKE 9
          GSSRKE
Sbjct: 17 GSSRKE 22
>XP_006716588
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IAGSSRKE 9
          +AG+SR+E
Sbjct: 33 VAGASRQE 40
>XP_005250881
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_005250880
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006716587
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006716586
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006716585
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_006716584
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 399 VAGASRQE 406
>XP_005250878
          Length = 648

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 400 VAGASRQE 407
>XP_006716582
          Length = 687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 439 VAGASRQE 446
>XP_005250877
          Length = 688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IAGSSRKE 9
           +AG+SR+E
Sbjct: 440 VAGASRQE 447
>XP_006710494
          Length = 1152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IAGSSRKE 9
           +AG +RKE
Sbjct: 949 VAGQTRKE 956
>XP_006710492
          Length = 1351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    IAGSSRKE 9
            +AG +RKE
Sbjct: 1148 VAGQTRKE 1155
>XP_006710491
          Length = 1496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    IAGSSRKE 9
            +AG +RKE
Sbjct: 1293 VAGQTRKE 1300
>XP_006710490
          Length = 2158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    IAGSSRKE 9
            +AG +RKE
Sbjct: 1955 VAGQTRKE 1962
>XP_006710489
          Length = 2185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    IAGSSRKE 9
            +AG +RKE
Sbjct: 1982 VAGQTRKE 1989
>NP_065869
          Length = 2458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  IAGSSRKE 9
          I GSSR+E
Sbjct: 29 ILGSSRRE 36
>NP_004516
          Length = 4655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FIAGSSRKE 9
           F+ GS+RK+
Sbjct: 542 FMDGSNRKD 550
>NP_001177894
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FIAGSSRKE 9
            ++ GS+RK+
Sbjct: 1152 YLCGSNRKD 1160
>NP_001177893
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FIAGSSRKE 9
            ++ GS+RK+
Sbjct: 1152 YLCGSNRKD 1160
>NP_932072
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FIAGSSRKE 9
            ++ GS+RK+
Sbjct: 1152 YLCGSNRKD 1160
>NP_003444
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FIAGSSRKE 9
            ++ GS+RK+
Sbjct: 1152 YLCGSNRKD 1160
>NP_055486
          Length = 1083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  IAGSSRKE 9
          + G+SRKE
Sbjct: 16 LGGASRKE 23
>NP_006175
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FIAGSSRKE 9
           F+A + RKE
Sbjct: 317 FLASTQRKE 325
>XP_005266578
          Length = 1290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FIAGSSRKE 9
            ++ GS+RK+
Sbjct: 1065 YLCGSNRKD 1073
>XP_005266576
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FIAGSSRKE 9
            ++ GS+RK+
Sbjct: 1152 YLCGSNRKD 1160
>XP_005266575
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FIAGSSRKE 9
            ++ GS+RK+
Sbjct: 1152 YLCGSNRKD 1160
>XP_005266577
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FIAGSSRKE 9
            ++ GS+RK+
Sbjct: 1152 YLCGSNRKD 1160
>XP_005266574
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FIAGSSRKE 9
            ++ GS+RK+
Sbjct: 1152 YLCGSNRKD 1160
>XP_005249622
          Length = 1021

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  IAGSSRKE 9
          + G+SRKE
Sbjct: 16 LGGASRKE 23
>XP_005249621
          Length = 1058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  IAGSSRKE 9
          + G+SRKE
Sbjct: 16 LGGASRKE 23
>XP_006712591
          Length = 3308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FIAGSSRKE 9
           F+ GS+RK+
Sbjct: 542 FMDGSNRKD 550
>XP_006712589
          Length = 4660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FIAGSSRKE 9
           F+ GS+RK+
Sbjct: 542 FMDGSNRKD 550
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.128    0.327 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 485,099
Number of extensions: 535
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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