Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     299
NP_001075109                                                           20     299
NP_001273127                                                           17    2528
NP_075046                                                              17    2528
NP_001273126                                                           17    2528
NP_001273120                                                           17    2528
NP_001273121                                                           17    2528
NP_004080                                                              17    3301
NP_085131                                                              17    3301
NP_003818                                                              17    4312
XP_006723517                                                           17    4312
NP_001094386                                                           17    4312
NP_036371                                                              16    5631
XP_005252892                                                           16    5631
NP_000247                                                              16    7355
NP_064516                                                              16    7355
NP_001026                                                              16    7355
NP_079537                                                              16    7355
XP_006718301                                                           16    7355
XP_006711873                                                           16    7355
XP_006711871                                                           16    7355
XP_006711870                                                           16    7355
XP_006711869                                                           16    7355
XP_006711868                                                           16    7355
XP_006711867                                                           16    7355
XP_006711866                                                           16    7355
XP_006711865                                                           16    7355
XP_005245405                                                           16    7355
XP_005245404                                                           16    7355
NP_001013373                                                           16    7355
NP_001004714                                                           16    7355
NP_001269557                                                           15    9605
NP_001269560                                                           15    9605
NP_000038                                                              15    9605
NP_002448                                                              15    9605
NP_001192183                                                           15    9605
NP_002529                                                              15    9605
NP_001229642                                                           15    9605
NP_001073942                                                           15    9605
NP_005157                                                              15    9605
NP_001019978                                                           15    9605
NP_060700                                                              15    9605
NP_689739                                                              15    9605
NP_476518                                                              15    9605
NP_995585                                                              15    9605
XP_006726276                                                           15    9605
XP_005274578                                                           15    9605
XP_005274576                                                           15    9605
XP_005274575                                                           15    9605
XP_005267180                                                           15    9605
XP_005267179                                                           15    9605
XP_005267178                                                           15    9605
XP_005265966                                                           15    9605
XP_006714575                                                           15    9605
XP_005246331                                                           15    9605
XP_005246330                                                           15    9605
XP_005264358                                                           15    9605
NP_055040                                                              15    9605
NP_001153068                                                           15    9605
NP_001003395                                                           15    9605
NP_003278                                                              15    9605
>NP_008835
          Length = 4128

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FFTSLAGGS 9
            FFTSL GGS
Sbjct: 1698 FFTSLTGGS 1706
>NP_001075109
          Length = 4097

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FFTSLAGGS 9
            FFTSL GGS
Sbjct: 1698 FFTSLTGGS 1706
>NP_001273127
          Length = 221

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FFTSLAGG 8
          FFTS+ GG
Sbjct: 83 FFTSVPGG 90
>NP_075046
          Length = 262

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FFTSLAGG 8
           FFTS+ GG
Sbjct: 125 FFTSVPGG 132
>NP_001273126
          Length = 230

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FFTSLAGG 8
          FFTS+ GG
Sbjct: 92 FFTSVPGG 99
>NP_001273120
          Length = 293

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FFTSLAGG 8
           FFTS+ GG
Sbjct: 156 FFTSVPGG 163
>NP_001273121
          Length = 263

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FFTSLAGG 8
           FFTS+ GG
Sbjct: 125 FFTSVPGG 132
>NP_004080
          Length = 134

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FFTSLAGG 8
          FF+SL GG
Sbjct: 24 FFSSLLGG 31
>NP_085131
          Length = 1019

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           F  SLAGGS
Sbjct: 317 FHDSLAGGS 325
>NP_003818
          Length = 295

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FFTSLAGGS 9
          FF+ L GGS
Sbjct: 27 FFSGLFGGS 35
>XP_006723517
          Length = 327

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FFTSLAGGS 9
          FF+ L GGS
Sbjct: 27 FFSGLFGGS 35
>NP_001094386
          Length = 435

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           FF +L GGS
Sbjct: 171 FFPALLGGS 179
>NP_036371
          Length = 399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FFTSLAGG 8
          FF+S+ GG
Sbjct: 91 FFSSIKGG 98
>XP_005252892
          Length = 417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FFTSLAGG 8
          FF+S+ GG
Sbjct: 91 FFSSIKGG 98
>NP_000247
          Length = 1274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TSLAGG 8
           TSLAGG
Sbjct: 274 TSLAGG 279
>NP_064516
          Length = 601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTSLAGGS 9
           F+SLAG S
Sbjct: 306 FSSLAGNS 313
>NP_001026
          Length = 4967

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FFTSLAG 7
            FF SLAG
Sbjct: 3789 FFQSLAG 3795
>NP_079537
          Length = 125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FFTSLAG 7
           F TSLAG
Sbjct: 112 FLTSLAG 118
>XP_006718301
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TSLAGG 8
           TSLAGG
Sbjct: 274 TSLAGG 279
>XP_006711873
          Length = 4954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FFTSLAG 7
            FF SLAG
Sbjct: 3776 FFQSLAG 3782
>XP_006711871
          Length = 4906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FFTSLAG 7
            FF SLAG
Sbjct: 3728 FFQSLAG 3734
>XP_006711870
          Length = 4965

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FFTSLAG 7
            FF SLAG
Sbjct: 3787 FFQSLAG 3793
>XP_006711869
          Length = 4973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FFTSLAG 7
            FF SLAG
Sbjct: 3795 FFQSLAG 3801
>XP_006711868
          Length = 4975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FFTSLAG 7
            FF SLAG
Sbjct: 3797 FFQSLAG 3803
>XP_006711867
          Length = 4977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FFTSLAG 7
            FF SLAG
Sbjct: 3799 FFQSLAG 3805
>XP_006711866
          Length = 4984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FFTSLAG 7
            FF SLAG
Sbjct: 3806 FFQSLAG 3812
>XP_006711865
          Length = 4985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FFTSLAG 7
            FF SLAG
Sbjct: 3807 FFQSLAG 3813
>XP_005245405
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTSLAGGS 9
           F+SLAG S
Sbjct: 306 FSSLAGNS 313
>XP_005245404
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTSLAGGS 9
           F+SLAG S
Sbjct: 306 FSSLAGNS 313
>NP_001013373
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           F  SLAGG+
Sbjct: 140 FCASLAGGA 148
>NP_001004714
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FFTSLAGGS 9
           FF  L GGS
Sbjct: 102 FFMHLLGGS 110
>NP_001269557
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           +FTS  GGS
Sbjct: 374 YFTSDHGGS 382
>NP_001269560
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           +FTS  GGS
Sbjct: 304 YFTSDHGGS 312
>NP_000038
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           +FTS  GGS
Sbjct: 349 YFTSDHGGS 357
>NP_002448
          Length = 5179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SLAGGS 9
          SLAGGS
Sbjct: 16 SLAGGS 21
>NP_001192183
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSLAGGS 9
           TSL GGS
Sbjct: 95  TSLLGGS 101
>NP_002529
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSLAGGS 9
           TSL GGS
Sbjct: 95  TSLLGGS 101
>NP_001229642
          Length = 102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SLAGGS 9
          SLAGGS
Sbjct: 92 SLAGGS 97
>NP_001073942
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FFTSLAG 7
           FFT L+G
Sbjct: 420 FFTKLSG 426
>NP_005157
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SLAGGS 9
          SLAGGS
Sbjct: 39 SLAGGS 44
>NP_001019978
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SLAGGS 9
          SLAGGS
Sbjct: 39 SLAGGS 44
>NP_060700
          Length = 1156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           F T++ GGS
Sbjct: 211 FLTAVQGGS 219
>NP_689739
          Length = 1143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FFTSLAG 7
           FF+SL+G
Sbjct: 220 FFSSLSG 226
>NP_476518
          Length = 1136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FFTSLAG 7
           FF+SL+G
Sbjct: 220 FFSSLSG 226
>NP_995585
          Length = 1104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FFTSLAG 7
           FF+SL+G
Sbjct: 220 FFSSLSG 226
>XP_006726276
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSLAGGS 9
           TSL GGS
Sbjct: 95  TSLLGGS 101
>XP_005274578
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           +FTS  GGS
Sbjct: 295 YFTSDHGGS 303
>XP_005274576
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           +FTS  GGS
Sbjct: 349 YFTSDHGGS 357
>XP_005274575
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           +FTS  GGS
Sbjct: 358 YFTSDHGGS 366
>XP_005267180
          Length = 175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SLAGGS 9
           SLAGGS
Sbjct: 160 SLAGGS 165
>XP_005267179
          Length = 175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SLAGGS 9
           SLAGGS
Sbjct: 160 SLAGGS 165
>XP_005267178
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SLAGGS 9
           SLAGGS
Sbjct: 176 SLAGGS 181
>XP_005265966
          Length = 891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TSLAGGS 9
           TS++GGS
Sbjct: 147 TSISGGS 153
>XP_006714575
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TSLAGGS 9
           TSL GGS
Sbjct: 95  TSLLGGS 101
>XP_005246331
          Length = 1006

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  FFTSLAG 7
          FF+SL+G
Sbjct: 21 FFSSLSG 27
>XP_005246330
          Length = 1205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FFTSLAG 7
           FF+SL+G
Sbjct: 220 FFSSLSG 226
>XP_005264358
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FFTSLAG 7
           FFT L+G
Sbjct: 420 FFTKLSG 426
>NP_055040
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  FTSLAGG 8
          FT+L GG
Sbjct: 76 FTTLVGG 82
>NP_001153068
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FFTSLAGGS 9
           FF+S  GG+
Sbjct: 180 FFSSQVGGN 188
>NP_001003395
          Length = 175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SLAGGS 9
           SLAGGS
Sbjct: 160 SLAGGS 165
>NP_003278
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SLAGGS 9
           SLAGGS
Sbjct: 189 SLAGGS 194
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.138    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 652,944
Number of extensions: 1086
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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