Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              19     869
NP_001120972                                                           19     869
XP_006716054                                                           19     869
XP_006716053                                                           19     869
XP_006716052                                                           19     869
XP_006716051                                                           19     869
NP_003649                                                              17    4312
NP_001002811                                                           16    5631
NP_001096068                                                           16    5631
NP_001096067                                                           16    5631
NP_001096069                                                           16    5631
NP_001096070                                                           16    5631
XP_005276195                                                           16    5631
XP_006711712                                                           16    5631
XP_006711711                                                           16    5631
XP_005277503                                                           16    5631
XP_005273038                                                           16    5631
XP_006711708                                                           16    5631
XP_005277500                                                           16    5631
XP_006711707                                                           16    5631
XP_005277499                                                           16    5631
XP_006711706                                                           16    5631
XP_006711705                                                           16    5631
XP_005277559                                                           16    5631
XP_006710144                                                           16    5631
NP_036336                                                              16    5631
XP_006721104                                                           16    7355
XP_005255321                                                           16    7355
NP_775889                                                              16    7355
NP_001005517                                                           16    7355
NP_001122318                                                           15    9605
NP_001122320                                                           15    9605
NP_001122321                                                           15    9605
NP_001122317                                                           15    9605
NP_003063                                                              15    9605
NP_001122319                                                           15    9605
NP_001122316                                                           15    9605
NP_003061                                                              15    9605
NP_001276325                                                           15    9605
NP_620614                                                              15    9605
NP_001276326                                                           15    9605
NP_733793                                                              15    9605
NP_689856                                                              15    9605
NP_037534                                                              15    9605
NP_068777                                                              15    9605
XP_005260092                                                           15    9605
XP_005260091                                                           15    9605
XP_005260090                                                           15    9605
XP_005260089                                                           15    9605
XP_005260088                                                           15    9605
XP_005260087                                                           15    9605
XP_005260085                                                           15    9605
XP_006722910                                                           15    9605
XP_006722909                                                           15    9605
XP_006722908                                                           15    9605
>NP_000236
          Length = 1390

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           FFMLD ILS
Sbjct: 820 FFMLDGILS 828
>NP_001120972
          Length = 1408

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           FFMLD ILS
Sbjct: 838 FFMLDGILS 846
>XP_006716054
          Length = 960

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           FFMLD ILS
Sbjct: 390 FFMLDGILS 398
>XP_006716053
          Length = 960

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           FFMLD ILS
Sbjct: 390 FFMLDGILS 398
>XP_006716052
          Length = 1409

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           FFMLD ILS
Sbjct: 839 FFMLDGILS 847
>XP_006716051
          Length = 1427

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           FFMLD ILS
Sbjct: 857 FFMLDGILS 865
>NP_003649
          Length = 279

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  FMLDRILS 9
          FM+D ILS
Sbjct: 25 FMIDEILS 32
>NP_001002811
          Length = 1132

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>NP_001096068
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           +F+LD ILS
Sbjct: 201 WFLLDSILS 209
>NP_001096067
          Length = 596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           +F+LD ILS
Sbjct: 201 WFLLDSILS 209
>NP_001096069
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           +F+LD ILS
Sbjct: 201 WFLLDSILS 209
>NP_001096070
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FFMLDRILS 9
           +F+LD ILS
Sbjct: 201 WFLLDSILS 209
>XP_005276195
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_006711712
          Length = 2473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_006711711
          Length = 2482

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_005277503
          Length = 2498

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_005273038
          Length = 2509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_006711708
          Length = 2512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_005277500
          Length = 2525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_006711707
          Length = 2553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_005277499
          Length = 2561

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_006711706
          Length = 2591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_006711705
          Length = 2592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_005277559
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>XP_006710144
          Length = 564

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FMLDRI 7
          FMLDRI
Sbjct: 56 FMLDRI 61
>NP_036336
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FMLDRILS 9
           FMLDR+ +
Sbjct: 145 FMLDRVFN 152
>XP_006721104
          Length = 193

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  FMLDRIL 8
          F+LDR+L
Sbjct: 52 FLLDRLL 58
>XP_005255321
          Length = 205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  FMLDRIL 8
          F+LDR+L
Sbjct: 52 FLLDRLL 58
>NP_775889
          Length = 244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  FMLDRIL 8
          F+LDR+L
Sbjct: 52 FLLDRLL 58
>NP_001005517
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FFMLDRILS 9
          FF  DRI+S
Sbjct: 85 FFSEDRIIS 93
>NP_001122318
          Length = 1616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>NP_001122320
          Length = 1613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>NP_001122321
          Length = 1679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>NP_001122317
          Length = 1617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>NP_003063
          Length = 1647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>NP_001122319
          Length = 1614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>NP_001122316
          Length = 1647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>NP_003061
          Length = 1590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1052 FELLDRIL 1059
>NP_001276325
          Length = 1590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1052 FELLDRIL 1059
>NP_620614
          Length = 1572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1052 FELLDRIL 1059
>NP_001276326
          Length = 1514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 994  FELLDRIL 1001
>NP_733793
          Length = 1280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  MLDRIL 8
          MLDRIL
Sbjct: 48 MLDRIL 53
>NP_689856
          Length = 1749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FMLDRILS 9
            F+LDRI S
Sbjct: 1292 FLLDRINS 1299
>NP_037534
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FFMLDRILS 9
           FF L +ILS
Sbjct: 295 FFALGKILS 303
>NP_068777
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FMLDRILS 9
           F +DRILS
Sbjct: 176 FGIDRILS 183
>XP_005260092
          Length = 1613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>XP_005260091
          Length = 1614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>XP_005260090
          Length = 1616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>XP_005260089
          Length = 1617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>XP_005260088
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>XP_005260087
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>XP_005260085
          Length = 1650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>XP_006722910
          Length = 1678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>XP_006722909
          Length = 1679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
>XP_006722908
          Length = 1679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FFMLDRIL 8
            F +LDRIL
Sbjct: 1082 FELLDRIL 1089
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.358    0.166    0.480 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 420,563
Number of extensions: 634
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.1 bits)
S2: 28 (15.4 bits)

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