Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000305                                                              19     665
XP_006717989                                                           19     665
NP_055553                                                              17    2528
XP_005257924                                                           17    2528
XP_005257923                                                           17    2528
XP_005257922                                                           17    2528
XP_005257921                                                           17    2528
XP_006722263                                                           17    2528
XP_005257920                                                           17    2528
NP_055510                                                              17    4312
NP_066918                                                              17    4312
XP_005256934                                                           17    4312
XP_006721670                                                           17    4312
XP_006712194                                                           17    4312
XP_006712193                                                           17    4312
XP_006712192                                                           17    4312
XP_006712191                                                           17    4312
NP_001091084                                                           16    5631
NP_116581                                                              16    5631
NP_006225                                                              16    5631
XP_006716096                                                           16    5631
XP_006716095                                                           16    5631
XP_005250509                                                           16    5631
NP_114116                                                              16    7355
NP_872292                                                              16    7355
XP_006724188                                                           16    7355
XP_005261382                                                           16    7355
NP_001182121                                                           15    9605
NP_001091982                                                           15    9605
NP_689560                                                              15    9605
NP_006249                                                              15    9605
NP_116231                                                              15    9605
NP_005269                                                              15    9605
NP_001001996                                                           15    9605
NP_001001995                                                           15    9605
NP_001001994                                                           15    9605
XP_005274547                                                           15    9605
XP_005274546                                                           15    9605
XP_005255403                                                           15    9605
XP_005270028                                                           15    9605
XP_005270027                                                           15    9605
XP_005250714                                                           15    9605
XP_005250712                                                           15    9605
>NP_000305
          Length = 403

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           FETI MFSG
Sbjct: 200 FETIPMFSG 208
>XP_006717989
          Length = 388

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           FETI MFSG
Sbjct: 185 FETIPMFSG 193
>NP_055553
          Length = 1356

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ET+L FSG
Sbjct: 430 ETVLFFSG 437
>XP_005257924
          Length = 1122

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ET+L FSG
Sbjct: 162 ETVLFFSG 169
>XP_005257923
          Length = 1131

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ET+L FSG
Sbjct: 171 ETVLFFSG 178
>XP_005257922
          Length = 1366

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ET+L FSG
Sbjct: 440 ETVLFFSG 447
>XP_005257921
          Length = 1370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ET+L FSG
Sbjct: 440 ETVLFFSG 447
>XP_006722263
          Length = 1390

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ET+L FSG
Sbjct: 430 ETVLFFSG 437
>XP_005257920
          Length = 1390

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ET+L FSG
Sbjct: 430 ETVLFFSG 437
>NP_055510
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ETIL +SG
Sbjct: 876 ETILQYSG 883
>NP_066918
          Length = 635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           F+T++MF G
Sbjct: 205 FQTLVMFLG 213
>XP_005256934
          Length = 1434

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ETIL +SG
Sbjct: 876 ETILQYSG 883
>XP_006721670
          Length = 1471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ETILMFSG 9
           ETIL +SG
Sbjct: 876 ETILQYSG 883
>XP_006712194
          Length = 362

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           F+T++MF G
Sbjct: 205 FQTLVMFLG 213
>XP_006712193
          Length = 635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           F+T++MF G
Sbjct: 205 FQTLVMFLG 213
>XP_006712192
          Length = 635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           F+T++MF G
Sbjct: 205 FQTLVMFLG 213
>XP_006712191
          Length = 635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           F+T++MF G
Sbjct: 205 FQTLVMFLG 213
>NP_001091084
          Length = 115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FETILMFSG 9
          FE+ L+F G
Sbjct: 7  FESFLLFEG 15
>NP_116581
          Length = 115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FETILMFSG 9
          FE+ L+F G
Sbjct: 7  FESFLLFEG 15
>NP_006225
          Length = 117

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FETILMFSG 9
          FE+ L+F G
Sbjct: 7  FESFLLFEG 15
>XP_006716096
          Length = 115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FETILMFSG 9
          FE+ L+F G
Sbjct: 7  FESFLLFEG 15
>XP_006716095
          Length = 115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FETILMFSG 9
          FE+ L+F G
Sbjct: 7  FESFLLFEG 15
>XP_005250509
          Length = 159

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FETILMFSG 9
          FE+ L+F G
Sbjct: 7  FESFLLFEG 15
>NP_114116
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FETILMFSG 9
           F+T + FSG
Sbjct: 262 FDTYITFSG 270
>NP_872292
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FETILMFSG 9
           F+T + FSG
Sbjct: 262 FDTYITFSG 270
>XP_006724188
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FETILMFSG 9
           F+T + FSG
Sbjct: 243 FDTYITFSG 251
>XP_005261382
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FETILMFSG 9
           F+T + FSG
Sbjct: 243 FDTYITFSG 251
>NP_001182121
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FETILMFSG 9
          FET ++F G
Sbjct: 65 FETSIIFCG 73
>NP_001091982
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           F+TI+M +G
Sbjct: 197 FQTIMMRTG 205
>NP_689560
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FETILMFSG 9
          FET ++F G
Sbjct: 65 FETSIIFCG 73
>NP_006249
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           F+TI+M +G
Sbjct: 212 FQTIMMRTG 220
>NP_116231
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FETILMF 7
           F T+LMF
Sbjct: 525 FHTLLMF 531
>NP_005269
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TILMFSG 9
          TIL FSG
Sbjct: 41 TILCFSG 47
>NP_001001996
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TILMFSG 9
          TIL FSG
Sbjct: 81 TILCFSG 87
>NP_001001995
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TILMFSG 9
          TIL FSG
Sbjct: 81 TILCFSG 87
>NP_001001994
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TILMFSG 9
          TIL FSG
Sbjct: 22 TILCFSG 28
>XP_005274547
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TILMFSG 9
          TIL FSG
Sbjct: 22 TILCFSG 28
>XP_005274546
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TILMFSG 9
          TIL FSG
Sbjct: 41 TILCFSG 47
>XP_005255403
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ETILMFS 8
          ET+L+FS
Sbjct: 5  ETLLLFS 11
>XP_005270028
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           F+TI+M +G
Sbjct: 117 FQTIMMRTG 125
>XP_005270027
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FETILMFSG 9
           F+TI+M +G
Sbjct: 212 FQTIMMRTG 220
>XP_005250714
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FETILMF 7
           F T+LMF
Sbjct: 483 FHTLLMF 489
>XP_005250712
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FETILMF 7
           F T+LMF
Sbjct: 524 FHTLLMF 530
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.150    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 351,941
Number of extensions: 434
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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