Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           20     390
NP_004561                                                              20     390
XP_005253450                                                           20     390
XP_006719151                                                           20     390
NP_055259                                                              17    2528
NP_001273343                                                           17    2528
NP_149109                                                              17    4312
NP_444256                                                              16    5631
NP_444254                                                              16    5631
NP_444253                                                              16    5631
NP_444255                                                              16    5631
NP_036228                                                              16    5631
NP_006222                                                              16    5631
NP_001265092                                                           16    5631
NP_001265091                                                           16    5631
NP_005777                                                              16    5631
NP_005725                                                              16    5631
NP_001041665                                                           16    5631
NP_079414                                                              16    5631
XP_005266698                                                           16    5631
XP_005266697                                                           16    5631
XP_005266602                                                           16    5631
XP_006718183                                                           16    5631
XP_005252786                                                           16    5631
XP_005247551                                                           16    5631
XP_005247550                                                           16    5631
XP_006713712                                                           16    5631
XP_005247549                                                           16    5631
NP_001188386                                                           16    7355
NP_938207                                                              16    7355
NP_112562                                                              16    7355
NP_001393                                                              16    7355
NP_001013863                                                           16    7355
NP_060190                                                              16    7355
NP_001193856                                                           16    7355
XP_005259649                                                           16    7355
XP_006722855                                                           16    7355
XP_006722854                                                           16    7355
XP_006722853                                                           16    7355
XP_006722041                                                           16    7355
XP_005257576                                                           16    7355
XP_006722040                                                           16    7355
XP_006722039                                                           16    7355
XP_005257575                                                           16    7355
XP_006715067                                                           16    7355
NP_038202                                                              15    9605
NP_000622                                                              15    9605
NP_751895                                                              15    9605
NP_004691                                                              15    9605
NP_036552                                                              15    9605
NP_001222                                                              15    9605
NP_054828                                                              15    9605
NP_689472                                                              15    9605
NP_006697                                                              15    9605
NP_001035095                                                           15    9605
XP_006720120                                                           15    9605
XP_006720119                                                           15    9605
XP_006716465                                                           15    9605
XP_005268424                                                           15    9605
XP_005268423                                                           15    9605
XP_005268422                                                           15    9605
NP_689659                                                              15    9605
>NP_001275701
          Length = 1486

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  FEQIVDEIS 9
          F+QIVDEIS
Sbjct: 40 FDQIVDEIS 48
>NP_004561
          Length = 1445

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  FEQIVDEIS 9
          F+QIVDEIS
Sbjct: 40 FDQIVDEIS 48
>XP_005253450
          Length = 1486

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  FEQIVDEIS 9
          F+QIVDEIS
Sbjct: 40 FDQIVDEIS 48
>XP_006719151
          Length = 1486

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  FEQIVDEIS 9
          F+QIVDEIS
Sbjct: 40 FDQIVDEIS 48
>NP_055259
          Length = 666

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FEQIVDEI 8
           FEQ+VD I
Sbjct: 325 FEQVVDRI 332
>NP_001273343
          Length = 667

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FEQIVDEI 8
           FEQ+VD I
Sbjct: 325 FEQVVDRI 332
>NP_149109
          Length = 596

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FEQIVDE 7
           FE+IVDE
Sbjct: 368 FERIVDE 374
>NP_444256
          Length = 1794

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FEQIVDE 7
            FE+I+DE
Sbjct: 1478 FERIIDE 1484
>NP_444254
          Length = 1845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FEQIVDE 7
            FE+I+DE
Sbjct: 1478 FERIIDE 1484
>NP_444253
          Length = 1914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FEQIVDE 7
            FE+I+DE
Sbjct: 1547 FERIIDE 1553
>NP_444255
          Length = 1863

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FEQIVDE 7
            FE+I+DE
Sbjct: 1547 FERIIDE 1553
>NP_036228
          Length = 709

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  FEQIVDEIS 9
          F +++DE+S
Sbjct: 89 FSKVIDELS 97
>NP_006222
          Length = 2286

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FEQIVDEI 8
           FE++ DEI
Sbjct: 596 FEEVCDEI 603
>NP_001265092
          Length = 1194

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QIVDEIS 9
           QIVDE+S
Sbjct: 142 QIVDELS 148
>NP_001265091
          Length = 1194

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QIVDEIS 9
           QIVDE+S
Sbjct: 142 QIVDELS 148
>NP_005777
          Length = 1032

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FEQIVDEIS 9
           FE+ +DE+S
Sbjct: 827 FEEALDELS 835
>NP_005725
          Length = 1215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QIVDEIS 9
           QIVDE+S
Sbjct: 142 QIVDELS 148
>NP_001041665
          Length = 1194

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QIVDEIS 9
           QIVDE+S
Sbjct: 142 QIVDELS 148
>NP_079414
          Length = 944

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FEQIVDEI 8
          FE ++DEI
Sbjct: 6  FEMVLDEI 13
>XP_005266698
          Length = 1032

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FEQIVDEIS 9
           FE+ +DE+S
Sbjct: 827 FEEALDELS 835
>XP_005266697
          Length = 1077

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FEQIVDEIS 9
           FE+ +DE+S
Sbjct: 872 FEEALDELS 880
>XP_005266602
          Length = 922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FEQIVDEI 8
          FE ++DEI
Sbjct: 6  FEMVLDEI 13
>XP_006718183
          Length = 1215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QIVDEIS 9
           QIVDE+S
Sbjct: 142 QIVDELS 148
>XP_005252786
          Length = 1215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QIVDEIS 9
           QIVDE+S
Sbjct: 142 QIVDELS 148
>XP_005247551
          Length = 1855

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FEQIVDE 7
            FE+I+DE
Sbjct: 1488 FERIIDE 1494
>XP_005247550
          Length = 1856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FEQIVDE 7
            FE+I+DE
Sbjct: 1489 FERIIDE 1495
>XP_006713712
          Length = 1923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FEQIVDE 7
            FE+I+DE
Sbjct: 1557 FERIIDE 1563
>XP_005247549
          Length = 1924

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FEQIVDE 7
            FE+I+DE
Sbjct: 1557 FERIIDE 1563
>NP_001188386
          Length = 1497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQI+DE+
Sbjct: 758 EQILDEV 764
>NP_938207
          Length = 1491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQI+DE+
Sbjct: 752 EQILDEV 758
>NP_112562
          Length = 1451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQI+DE+
Sbjct: 752 EQILDEV 758
>NP_001393
          Length = 462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FEQIVDEIS 9
           +E+IV E+S
Sbjct: 167 YEEIVKEVS 175
>NP_001013863
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FEQIVDEI 8
          FE++ DEI
Sbjct: 68 FEKLTDEI 75
>NP_060190
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FEQIVDEI 8
          FE++ DEI
Sbjct: 68 FEKLTDEI 75
>NP_001193856
          Length = 4707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FEQIVDEI 8
            FEQ +DE+
Sbjct: 1262 FEQEIDEL 1269
>XP_005259649
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FEQIVDEI 8
           FE++ DEI
Sbjct: 145 FEKLTDEI 152
>XP_006722855
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FEQIVDEI 8
           FE++ DEI
Sbjct: 145 FEKLTDEI 152
>XP_006722854
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FEQIVDEI 8
           FE++ DEI
Sbjct: 145 FEKLTDEI 152
>XP_006722853
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FEQIVDEI 8
           FE++ DEI
Sbjct: 145 FEKLTDEI 152
>XP_006722041
          Length = 1445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQI+DE+
Sbjct: 755 EQILDEV 761
>XP_005257576
          Length = 1454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQI+DE+
Sbjct: 755 EQILDEV 761
>XP_006722040
          Length = 1466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQI+DE+
Sbjct: 755 EQILDEV 761
>XP_006722039
          Length = 1491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQI+DE+
Sbjct: 752 EQILDEV 758
>XP_005257575
          Length = 1494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQI+DE+
Sbjct: 755 EQILDEV 761
>XP_006715067
          Length = 4707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FEQIVDEI 8
            FEQ +DE+
Sbjct: 1262 FEQEIDEL 1269
>NP_038202
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  FEQIVDEIS 9
          FEQ+ D+++
Sbjct: 13 FEQLPDDVA 21
>NP_000622
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  FEQIVDEIS 9
          FEQ+ D+++
Sbjct: 13 FEQLPDDVA 21
>NP_751895
          Length = 641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QIVDEIS 9
           ++VDEIS
Sbjct: 554 EVVDEIS 560
>NP_004691
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QIVDEIS 9
           ++VDEIS
Sbjct: 608 EVVDEIS 614
>NP_036552
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EQIVDEIS 9
           E+I+D+IS
Sbjct: 239 EEILDQIS 246
>NP_001222
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FEQIVDEI 8
           FE I DEI
Sbjct: 173 FENIEDEI 180
>NP_054828
          Length = 1390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FEQIVDEI 8
            FEQ+ +EI
Sbjct: 1097 FEQLCEEI 1104
>NP_689472
          Length = 1910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   EQIVDEIS 9
           EQ+V+E++
Sbjct: 744 EQVVEEVT 751
>NP_006697
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FEQIVDEIS 9
           F Q++DE S
Sbjct: 961 FRQLLDETS 969
>NP_001035095
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FEQIVDEIS 9
           F Q++DE S
Sbjct: 940 FRQLLDETS 948
>XP_006720120
          Length = 1055

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQ++DEI
Sbjct: 885 EQLLDEI 891
>XP_006720119
          Length = 1094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQ++DEI
Sbjct: 924 EQLLDEI 930
>XP_006716465
          Length = 1826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    FEQIVDEI 8
            F Q+VD++
Sbjct: 1808 FHQLVDQV 1815
>XP_005268424
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FEQIVDEIS 9
           F Q++DE S
Sbjct: 917 FRQLLDETS 925
>XP_005268423
          Length = 1094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FEQIVDEIS 9
           F Q++DE S
Sbjct: 957 FRQLLDETS 965
>XP_005268422
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FEQIVDEIS 9
           F Q++DE S
Sbjct: 978 FRQLLDETS 986
>NP_689659
          Length = 1094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EQIVDEI 8
           EQ++DEI
Sbjct: 924 EQLLDEI 930
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.140    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 483,825
Number of extensions: 1253
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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