Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              23      60
XP_006714104                                                           23      60
XP_005265800                                                           23      60
XP_006714103                                                           23      60
XP_006714102                                                           23      60
NP_277037                                                              17    3301
NP_001158058                                                           17    3301
XP_006715212                                                           17    3301
XP_006715211                                                           17    3301
XP_006715210                                                           17    3301
XP_006715209                                                           17    3301
XP_006715208                                                           17    3301
XP_006715207                                                           17    3301
XP_006715206                                                           17    3301
XP_005249280                                                           17    3301
XP_006711681                                                           17    3301
XP_006711680                                                           17    3301
XP_005245637                                                           17    3301
NP_115921                                                              17    4312
XP_005267222                                                           17    4312
XP_006715597                                                           17    4312
XP_005248809                                                           17    4312
NP_001695                                                              17    4312
NP_060021                                                              16    5631
XP_006717867                                                           16    5631
NP_001990                                                              16    7355
NP_569079                                                              16    7355
NP_085130                                                              16    7355
NP_064520                                                              16    7355
NP_002010                                                              16    7355
NP_001153392                                                           16    7355
NP_000867                                                              16    7355
NP_001153503                                                           16    7355
NP_001153502                                                           16    7355
NP_115823                                                              16    7355
NP_004775                                                              16    7355
XP_005262074                                                           16    7355
XP_005262066                                                           16    7355
XP_006722988                                                           16    7355
XP_005249291                                                           16    7355
XP_005266053                                                           16    7355
XP_005266052                                                           16    7355
XP_005266051                                                           16    7355
XP_006714479                                                           16    7355
NP_001129981                                                           16    7355
NP_005859                                                              16    7355
NP_005889                                                              16    7355
NP_976240                                                              16    7355
NP_775807                                                              16    7355
NP_663780                                                              15    9605
NP_056101                                                              15    9605
NP_001124320                                                           15    9605
NP_055906                                                              15    9605
NP_115896                                                              15    9605
NP_001171672                                                           15    9605
NP_004901                                                              15    9605
NP_001693                                                              15    9605
NP_061170                                                              15    9605
NP_061915                                                              15    9605
XP_005258843                                                           15    9605
XP_005258842                                                           15    9605
XP_005258841                                                           15    9605
XP_006720146                                                           15    9605
XP_005267508                                                           15    9605
XP_005251072                                                           15    9605
XP_005250520                                                           15    9605
XP_006716093                                                           15    9605
XP_005250519                                                           15    9605
XP_006715291                                                           15    9605
XP_005272088                                                           15    9605
NP_071414                                                              15    9605
>NP_006197
          Length = 1089

 Score = 22.7 bits (47), Expect =    60
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FDSRQGFNG 9
           +DSRQGFNG
Sbjct: 172 YDSRQGFNG 180
>XP_006714104
          Length = 832

 Score = 22.7 bits (47), Expect =    60
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FDSRQGFNG 9
           +DSRQGFNG
Sbjct: 197 YDSRQGFNG 205
>XP_005265800
          Length = 1089

 Score = 22.7 bits (47), Expect =    60
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FDSRQGFNG 9
           +DSRQGFNG
Sbjct: 172 YDSRQGFNG 180
>XP_006714103
          Length = 1111

 Score = 22.7 bits (47), Expect =    60
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FDSRQGFNG 9
           +DSRQGFNG
Sbjct: 194 YDSRQGFNG 202
>XP_006714102
          Length = 1114

 Score = 22.7 bits (47), Expect =    60
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FDSRQGFNG 9
           +DSRQGFNG
Sbjct: 197 YDSRQGFNG 205
>NP_277037
          Length = 1200

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    FDSRQGFNG 9
            F SRQ  NG
Sbjct: 1024 FSSRQALNG 1032
>NP_001158058
          Length = 3708

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    SRQGFNG 9
            SRQGF G
Sbjct: 2322 SRQGFGG 2328
>XP_006715212
          Length = 741

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FDSRQGFNG 9
           F SRQ  NG
Sbjct: 565 FSSRQALNG 573
>XP_006715211
          Length = 1117

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FDSRQGFNG 9
           F SRQ  NG
Sbjct: 941 FSSRQALNG 949
>XP_006715210
          Length = 1129

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FDSRQGFNG 9
           F SRQ  NG
Sbjct: 953 FSSRQALNG 961
>XP_006715209
          Length = 1131

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FDSRQGFNG 9
           F SRQ  NG
Sbjct: 955 FSSRQALNG 963
>XP_006715208
          Length = 1200

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    FDSRQGFNG 9
            F SRQ  NG
Sbjct: 1024 FSSRQALNG 1032
>XP_006715207
          Length = 1212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    FDSRQGFNG 9
            F SRQ  NG
Sbjct: 1036 FSSRQALNG 1044
>XP_006715206
          Length = 1220

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    FDSRQGFNG 9
            F SRQ  NG
Sbjct: 1044 FSSRQALNG 1052
>XP_005249280
          Length = 1220

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    FDSRQGFNG 9
            F SRQ  NG
Sbjct: 1044 FSSRQALNG 1052
>XP_006711681
          Length = 3448

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    SRQGFNG 9
            SRQGF G
Sbjct: 2322 SRQGFGG 2328
>XP_006711680
          Length = 3617

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    SRQGFNG 9
            SRQGF G
Sbjct: 2231 SRQGFGG 2237
>XP_005245637
          Length = 3683

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    SRQGFNG 9
            SRQGF G
Sbjct: 2322 SRQGFGG 2328
>NP_115921
          Length = 1894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RQGFNG 9
            RQG+NG
Sbjct: 1321 RQGYNG 1326
>XP_005267222
          Length = 1819

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RQGFNG 9
            RQG+NG
Sbjct: 1246 RQGYNG 1251
>XP_006715597
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FDSRQGF 7
            FDS QGF
Sbjct: 1102 FDSLQGF 1108
>XP_005248809
          Length = 1522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FDSRQGF 7
            FDS QGF
Sbjct: 1135 FDSLQGF 1141
>NP_001695
          Length = 1522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    FDSRQGF 7
            FDS QGF
Sbjct: 1135 FDSLQGF 1141
>NP_060021
          Length = 1009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FDSRQGFNG 9
           +DS +G NG
Sbjct: 415 WDSEKGLNG 423
>XP_006717867
          Length = 896

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FDSRQGFNG 9
           +DS +G NG
Sbjct: 415 WDSEKGLNG 423
>NP_001990
          Length = 2912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FDSRQGF 7
            FD+RQ F
Sbjct: 2097 FDTRQSF 2103
>NP_569079
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DSRQGFNG 9
           D+R G NG
Sbjct: 414 DARAGLNG 421
>NP_085130
          Length = 729

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DSRQGFNG 9
           D R+G NG
Sbjct: 316 DHRRGLNG 323
>NP_064520
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DSRQGFNG 9
           D+R G NG
Sbjct: 439 DARAGLNG 446
>NP_002010
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FDSRQGF 7
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_001153392
          Length = 687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FDSRQGF 7
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_000867
          Length = 2491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDSRQGFN 8
           FDS+ GF+
Sbjct: 630 FDSQAGFS 637
>NP_001153503
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FDSRQGF 7
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_001153502
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FDSRQGF 7
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_115823
          Length = 2809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FDSRQGF 7
            FD+RQ F
Sbjct: 2010 FDTRQSF 2016
>NP_004775
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FDSRQGF 7
           FDS +GF
Sbjct: 801 FDSHKGF 807
>XP_005262074
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  SRQGFNG 9
          +RQGF G
Sbjct: 39 ARQGFEG 45
>XP_005262066
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  SRQGFNG 9
          +RQGF G
Sbjct: 39 ARQGFEG 45
>XP_006722988
          Length = 2818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FDSRQGF 7
            FD+RQ F
Sbjct: 2019 FDTRQSF 2025
>XP_005249291
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DSRQGFNG 9
           D+R G NG
Sbjct: 122 DARAGLNG 129
>XP_005266053
          Length = 704

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DSRQGFNG 9
           D R+G NG
Sbjct: 316 DHRRGLNG 323
>XP_005266052
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DSRQGFNG 9
           D R+G NG
Sbjct: 316 DHRRGLNG 323
>XP_005266051
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DSRQGFNG 9
           D R+G NG
Sbjct: 316 DHRRGLNG 323
>XP_006714479
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FDSRQGF 7
           FDS +GF
Sbjct: 801 FDSHKGF 807
>NP_001129981
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RQGFNG 9
           RQGF+G
Sbjct: 95  RQGFSG 100
>NP_005859
          Length = 118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  FDSRQGFNG 9
          FDS  GF G
Sbjct: 71 FDSTTGFLG 79
>NP_005889
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DSRQGFNG 9
           D +QG NG
Sbjct: 167 DLKQGLNG 174
>NP_976240
          Length = 694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DSRQGFNG 9
           D +QG NG
Sbjct: 167 DLKQGLNG 174
>NP_775807
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   FDSRQGFN 8
           FDSR  FN
Sbjct: 120 FDSRLKFN 127
>NP_663780
          Length = 1565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DSRQGFNG 9
           D+R+GF G
Sbjct: 393 DARRGFLG 400
>NP_056101
          Length = 1253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DSRQGFNG 9
           D+R+GF G
Sbjct: 393 DARRGFLG 400
>NP_001124320
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FDSRQGFN 8
           FD+ +GF+
Sbjct: 351 FDAHEGFS 358
>NP_055906
          Length = 1720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SRQGFNG 9
           SR+G NG
Sbjct: 903 SRRGLNG 909
>NP_115896
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FDSRQGFNG 9
           FDS Q  NG
Sbjct: 553 FDSDQFLNG 561
>NP_001171672
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FDSRQGFNG 9
           FDS Q  NG
Sbjct: 553 FDSDQFLNG 561
>NP_004901
          Length = 1244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FDSRQGFN 8
           FD+ +GF+
Sbjct: 351 FDAHEGFS 358
>NP_001693
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FDSRQGF 7
            FDS +GF
Sbjct: 1172 FDSLEGF 1178
>NP_061170
          Length = 728

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DSRQGFN 8
           +SR GFN
Sbjct: 538 ESRAGFN 544
>NP_061915
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SRQGFNG 9
           S QGF+G
Sbjct: 122 SHQGFSG 128
>XP_005258843
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FDSRQGFNG 9
          F+S  GF+G
Sbjct: 13 FESCSGFSG 21
>XP_005258842
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FDSRQGFNG 9
          F+S  GF+G
Sbjct: 13 FESCSGFSG 21
>XP_005258841
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FDSRQGFNG 9
          F+S  GF+G
Sbjct: 13 FESCSGFSG 21
>XP_006720146
          Length = 1226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SRQGFNG 9
           SR+G NG
Sbjct: 903 SRRGLNG 909
>XP_005267508
          Length = 1773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SRQGFNG 9
           SR+G NG
Sbjct: 903 SRRGLNG 909
>XP_005251072
          Length = 1586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FDSRQGF 7
            FDS +GF
Sbjct: 1169 FDSLEGF 1175
>XP_005250520
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SRQGFNG 9
           S QGF+G
Sbjct: 122 SHQGFSG 128
>XP_006716093
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SRQGFNG 9
           S QGF+G
Sbjct: 122 SHQGFSG 128
>XP_005250519
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SRQGFNG 9
           S QGF+G
Sbjct: 122 SHQGFSG 128
>XP_006715291
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FDSRQGFNG 9
           FDS Q  NG
Sbjct: 302 FDSDQFLNG 310
>XP_005272088
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DSRQGFN 8
           +SR GFN
Sbjct: 526 ESRAGFN 532
>NP_071414
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   FDSRQG 6
           FD RQG
Sbjct: 358 FDGRQG 363
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.147    0.465 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 623,967
Number of extensions: 1317
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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