Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              19     665
NP_996744                                                              17    4312
NP_008928                                                              17    4312
NP_996742                                                              17    4312
XP_006717618                                                           17    4312
XP_005269456                                                           17    4312
XP_006717617                                                           17    4312
XP_006717616                                                           17    4312
XP_006717615                                                           17    4312
XP_005269454                                                           17    4312
XP_005269453                                                           17    4312
XP_006717614                                                           17    4312
XP_006717613                                                           17    4312
XP_006717612                                                           17    4312
XP_005269452                                                           17    4312
XP_005269451                                                           17    4312
XP_006717611                                                           17    4312
XP_005269450                                                           17    4312
XP_005269449                                                           17    4312
XP_005269448                                                           17    4312
XP_005269447                                                           17    4312
XP_005269446                                                           17    4312
XP_005269445                                                           17    4312
NP_996743                                                              17    4312
NP_002728                                                              16    5631
NP_001245308                                                           16    7355
NP_003606                                                              16    7355
NP_001245309                                                           16    7355
NP_001243125                                                           16    7355
NP_001645                                                              16    7355
NP_001171486                                                           16    7355
NP_001171487                                                           16    7355
XP_006724592                                                           16    7355
XP_005265658                                                           16    7355
XP_005265657                                                           16    7355
XP_005265656                                                           16    7355
XP_005265655                                                           16    7355
XP_006713484                                                           16    7355
XP_005246752                                                           16    7355
XP_005246751                                                           16    7355
XP_006712706                                                           16    7355
XP_006712705                                                           16    7355
XP_006712704                                                           16    7355
XP_005246750                                                           16    7355
NP_071341                                                              16    7355
NP_001269416                                                           15    9605
NP_000938                                                              15    9605
NP_001269417                                                           15    9605
NP_001245204                                                           15    9605
NP_006288                                                              15    9605
NP_003615                                                              15    9605
NP_015561                                                              15    9605
NP_001017373                                                           15    9605
NP_001264114                                                           15    9605
NP_015559                                                              15    9605
XP_005259721                                                           15    9605
XP_005266885                                                           15    9605
XP_006712334                                                           15    9605
XP_006712333                                                           15    9605
XP_006712332                                                           15    9605
XP_005246357                                                           15    9605
XP_006712331                                                           15    9605
XP_005246356                                                           15    9605
NP_742067                                                              15    9605
NP_542786                                                              15    9605
>NP_004251
          Length = 1208

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FDRVKLVDS 9
           FD VKLVDS
Sbjct: 987 FDMVKLVDS 995
>NP_996744
          Length = 2948

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2040 FDNIELVDT 2048
>NP_008928
          Length = 1026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FDRVKLVDS 9
           FD ++LVD+
Sbjct: 118 FDNIELVDT 126
>NP_996742
          Length = 996

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FDRVKLVDS 9
           FD ++LVD+
Sbjct: 118 FDNIELVDT 126
>XP_006717618
          Length = 2826

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 1995 FDNIELVDT 2003
>XP_005269456
          Length = 2846

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2015 FDNIELVDT 2023
>XP_006717617
          Length = 2887

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_006717616
          Length = 2891

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_006717615
          Length = 2903

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_005269454
          Length = 2912

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 1973 FDNIELVDT 1981
>XP_005269453
          Length = 2922

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_006717614
          Length = 2938

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_006717613
          Length = 2948

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2040 FDNIELVDT 2048
>XP_006717612
          Length = 2950

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_005269452
          Length = 2954

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2015 FDNIELVDT 2023
>XP_005269451
          Length = 2957

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2018 FDNIELVDT 2026
>XP_006717611
          Length = 2964

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_005269450
          Length = 2968

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_005269449
          Length = 2969

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_005269448
          Length = 2979

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2040 FDNIELVDT 2048
>XP_005269447
          Length = 2980

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_005269446
          Length = 2999

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>XP_005269445
          Length = 2999

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FDRVKLVDS 9
            FD ++LVD+
Sbjct: 2060 FDNIELVDT 2068
>NP_996743
          Length = 1094

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FDRVKLVDS 9
           FD ++LVD+
Sbjct: 186 FDNIELVDT 194
>NP_002728
          Length = 672

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DRVKLVD 8
           DRVKL D
Sbjct: 332 DRVKLTD 338
>NP_001245308
          Length = 1131

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 936 FDRIKL 941
>NP_003606
          Length = 1214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FDRVKL 6
            FDR+KL
Sbjct: 1055 FDRIKL 1060
>NP_001245309
          Length = 1090

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 931 FDRIKL 936
>NP_001243125
          Length = 609

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           FD V+L+D
Sbjct: 404 FDMVQLID 411
>NP_001645
          Length = 606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           FD V+L+D
Sbjct: 401 FDMVQLID 408
>NP_001171486
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 956 FDRIKL 961
>NP_001171487
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 937 FDRIKL 942
>XP_006724592
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           FD V+L+D
Sbjct: 406 FDMVQLID 413
>XP_005265658
          Length = 1095

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 936 FDRIKL 941
>XP_005265657
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 918 FDRIKL 923
>XP_005265656
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 923 FDRIKL 928
>XP_005265655
          Length = 1126

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 931 FDRIKL 936
>XP_006713484
          Length = 1255

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FDRVKL 6
            FDR+KL
Sbjct: 1060 FDRIKL 1065
>XP_005246752
          Length = 1117

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 937 FDRIKL 942
>XP_005246751
          Length = 1147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 967 FDRIKL 972
>XP_006712706
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 968 FDRIKL 973
>XP_006712705
          Length = 1174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 994 FDRIKL 999
>XP_006712704
          Length = 1204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FDRVKL 6
            FDR+KL
Sbjct: 1024 FDRIKL 1029
>XP_005246750
          Length = 1205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FDRVKL 6
            FDR+KL
Sbjct: 1025 FDRIKL 1030
>NP_071341
          Length = 1088

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FDRVKL 6
           FDR+KL
Sbjct: 926 FDRIKL 931
>NP_001269416
          Length = 158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DRVKLVDS 9
          DRVKL+ S
Sbjct: 48 DRVKLLKS 55
>NP_000938
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DRVKLVDS 9
          DRVKL+ S
Sbjct: 48 DRVKLLKS 55
>NP_001269417
          Length = 158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DRVKLVDS 9
          DRVKL+ S
Sbjct: 48 DRVKLLKS 55
>NP_001245204
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FDRVKLV 7
           FD +KLV
Sbjct: 265 FDEIKLV 271
>NP_006288
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FDRVKLVDS 9
           +DRVK+V S
Sbjct: 125 WDRVKIVCS 133
>NP_003615
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DRVKLVD 8
           DRVKL++
Sbjct: 263 DRVKLIN 269
>NP_015561
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DRVKLVD 8
           DRVKL++
Sbjct: 268 DRVKLIN 274
>NP_001017373
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FDRVKLV 7
           FD +KLV
Sbjct: 265 FDEIKLV 271
>NP_001264114
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FDRVKLV 7
           FD +KLV
Sbjct: 289 FDEIKLV 295
>NP_015559
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DRVKLVD 8
           DRVKL++
Sbjct: 200 DRVKLIN 206
>XP_005259721
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DRVKLVD 8
           DRVKL++
Sbjct: 195 DRVKLIN 201
>XP_005266885
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FDRVKLV 7
           FD +KLV
Sbjct: 285 FDEIKLV 291
>XP_006712334
          Length = 1891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           F+R K+VD
Sbjct: 732 FERFKVVD 739
>XP_006712333
          Length = 1714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           F+R K+VD
Sbjct: 544 FERFKVVD 551
>XP_006712332
          Length = 1892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           F+R K+VD
Sbjct: 733 FERFKVVD 740
>XP_005246357
          Length = 1899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           F+R K+VD
Sbjct: 733 FERFKVVD 740
>XP_006712331
          Length = 1902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           F+R K+VD
Sbjct: 732 FERFKVVD 739
>XP_005246356
          Length = 1903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           F+R K+VD
Sbjct: 733 FERFKVVD 740
>NP_742067
          Length = 1888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FDRVKLVD 8
           F+R K+VD
Sbjct: 733 FERFKVVD 740
>NP_542786
          Length = 79

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  FDRVKL 6
          FDRVK+
Sbjct: 16 FDRVKM 21
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.146    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 412,199
Number of extensions: 655
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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