Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              20     390
NP_653080                                                              20     390
XP_005267292                                                           20     390
XP_005267291                                                           20     390
XP_005267290                                                           20     390
NP_005522                                                              17    3301
NP_001193496                                                           17    3301
XP_006711353                                                           17    3301
XP_005245184                                                           17    3301
NP_001231118                                                           17    4312
NP_001231121                                                           17    4312
NP_055564                                                              17    4312
NP_001231119                                                           17    4312
NP_001231120                                                           17    4312
NP_001231122                                                           17    4312
NP_002652                                                              17    4312
XP_006720406                                                           17    4312
XP_006720405                                                           17    4312
XP_006720404                                                           17    4312
XP_006720403                                                           17    4312
XP_006720402                                                           17    4312
XP_006720400                                                           17    4312
XP_006720399                                                           17    4312
NP_004690                                                              16    5631
NP_036267                                                              16    5631
NP_055299                                                              16    7355
XP_005245161                                                           16    7355
NP_037485                                                              16    7355
NP_060420                                                              15    9605
NP_057289                                                              15    9605
NP_055444                                                              15    9605
NP_073143                                                              15    9605
NP_001937                                                              15    9605
NP_001230271                                                           15    9605
NP_056053                                                              15    9605
NP_001155134                                                           15    9605
NP_001155133                                                           15    9605
XP_006725174                                                           15    9605
XP_006725173                                                           15    9605
XP_006725172                                                           15    9605
XP_006725171                                                           15    9605
XP_006725170                                                           15    9605
XP_006725169                                                           15    9605
XP_006725168                                                           15    9605
XP_006725167                                                           15    9605
XP_005257549                                                           15    9605
XP_005257548                                                           15    9605
XP_006720401                                                           15    9605
XP_005266099                                                           15    9605
XP_006716304                                                           15    9605
XP_006716303                                                           15    9605
XP_006716302                                                           15    9605
XP_005266098                                                           15    9605
XP_005266097                                                           15    9605
XP_005266096                                                           15    9605
XP_006716301                                                           15    9605
XP_006714899                                                           15    9605
XP_005265910                                                           15    9605
XP_006714898                                                           15    9605
XP_005265909                                                           15    9605
XP_005265908                                                           15    9605
XP_005265907                                                           15    9605
XP_006714336                                                           15    9605
>NP_005091
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EYDAVEMEK 9
           EYDAVE EK
Sbjct: 851 EYDAVEREK 859
>NP_653080
          Length = 1684

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EYDAVEMEK 9
           EYDAVE EK
Sbjct: 753 EYDAVEREK 761
>XP_005267292
          Length = 1677

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EYDAVEMEK 9
           EYDAVE EK
Sbjct: 746 EYDAVEREK 754
>XP_005267291
          Length = 1684

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EYDAVEMEK 9
           EYDAVE EK
Sbjct: 753 EYDAVEREK 761
>XP_005267290
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EYDAVEMEK 9
           EYDAVE EK
Sbjct: 851 EYDAVEREK 859
>NP_005522
          Length = 729

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           EY+  EMEK
Sbjct: 217 EYETPEMEK 225
>NP_001193496
          Length = 729

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           EY+  EMEK
Sbjct: 161 EYETPEMEK 169
>XP_006711353
          Length = 677

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           EY+  EMEK
Sbjct: 221 EYETPEMEK 229
>XP_005245184
          Length = 789

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           EY+  EMEK
Sbjct: 221 EYETPEMEK 229
>NP_001231118
          Length = 1644

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1334 HDAVEME 1340
>NP_001231121
          Length = 1504

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1237 HDAVEME 1243
>NP_055564
          Length = 1472

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1205 HDAVEME 1211
>NP_001231119
          Length = 1533

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1266 HDAVEME 1272
>NP_001231120
          Length = 1463

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1196 HDAVEME 1202
>NP_001231122
          Length = 1347

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1141 HDAVEME 1147
>NP_002652
          Length = 1265

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EYDAVEME 8
           +YDAV+M+
Sbjct: 305 KYDAVDMQ 312
>XP_006720406
          Length = 1591

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1281 HDAVEME 1287
>XP_006720405
          Length = 1347

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1281 HDAVEME 1287
>XP_006720404
          Length = 1477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1281 HDAVEME 1287
>XP_006720403
          Length = 1486

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1281 HDAVEME 1287
>XP_006720402
          Length = 1487

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1281 HDAVEME 1287
>XP_006720400
          Length = 1526

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1281 HDAVEME 1287
>XP_006720399
          Length = 1548

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEME
Sbjct: 1281 HDAVEME 1287
>NP_004690
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  YDAVEME 8
          YDAVE E
Sbjct: 53 YDAVEAE 59
>NP_036267
          Length = 325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  YDAVEME 8
          YDAVE E
Sbjct: 53 YDAVEAE 59
>NP_055299
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   EYDAVEM 7
           +YD VEM
Sbjct: 113 DYDVVEM 119
>XP_005245161
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DAVEME 8
           DAVEME
Sbjct: 257 DAVEME 262
>NP_037485
          Length = 345

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DAVEME 8
           DAVEME
Sbjct: 296 DAVEME 301
>NP_060420
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E DA+ +EK
Sbjct: 484 EIDAISVEK 492
>NP_057289
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EYDAVEMEK 9
           +YD VE+E+
Sbjct: 105 KYDFVEVEE 113
>NP_055444
          Length = 1344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 466 EWDSVEM 472
>NP_073143
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   YDAVEMEK 9
           YD V+M+K
Sbjct: 174 YDIVKMKK 181
>NP_001937
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   YDAVEMEK 9
           YD V+M+K
Sbjct: 320 YDIVKMKK 327
>NP_001230271
          Length = 1030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E DA+ +EK
Sbjct: 484 EIDAISVEK 492
>NP_056053
          Length = 1113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E  AVE+EK
Sbjct: 819 EQTAVELEK 827
>NP_001155134
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E  AVE+EK
Sbjct: 819 EQTAVELEK 827
>NP_001155133
          Length = 1119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E  AVE+EK
Sbjct: 819 EQTAVELEK 827
>XP_006725174
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 428 EWDSVEM 434
>XP_006725173
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 491 EWDSVEM 497
>XP_006725172
          Length = 1329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 451 EWDSVEM 457
>XP_006725171
          Length = 1330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 452 EWDSVEM 458
>XP_006725170
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 467 EWDSVEM 473
>XP_006725169
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 491 EWDSVEM 497
>XP_006725168
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 490 EWDSVEM 496
>XP_006725167
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 491 EWDSVEM 497
>XP_005257549
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E DA+ +EK
Sbjct: 484 EIDAISVEK 492
>XP_005257548
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  EYDAVEMEK 9
          E DA+ +EK
Sbjct: 91 EIDAISVEK 99
>XP_006720401
          Length = 1504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    YDAVEME 8
            +DAVEM+
Sbjct: 1281 HDAVEMD 1287
>XP_005266099
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 428 EWDSVEM 434
>XP_006716304
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 491 EWDSVEM 497
>XP_006716303
          Length = 1329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 451 EWDSVEM 457
>XP_006716302
          Length = 1330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 452 EWDSVEM 458
>XP_005266098
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 467 EWDSVEM 473
>XP_005266097
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 491 EWDSVEM 497
>XP_005266096
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 490 EWDSVEM 496
>XP_006716301
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EYDAVEM 7
           E+D+VEM
Sbjct: 491 EWDSVEM 497
>XP_006714899
          Length = 881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E  AVE+EK
Sbjct: 581 EQTAVELEK 589
>XP_005265910
          Length = 1112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E  AVE+EK
Sbjct: 819 EQTAVELEK 827
>XP_006714898
          Length = 1117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E  AVE+EK
Sbjct: 824 EQTAVELEK 832
>XP_005265909
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E  AVE+EK
Sbjct: 824 EQTAVELEK 832
>XP_005265908
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E  AVE+EK
Sbjct: 824 EQTAVELEK 832
>XP_005265907
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EYDAVEMEK 9
           E  AVE+EK
Sbjct: 824 EQTAVELEK 832
>XP_006714336
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EYDAVEMEK 9
           +YD VE+E+
Sbjct: 94  KYDFVEVEE 102
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.120    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 476,067
Number of extensions: 793
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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