Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              18    1135
XP_005266703                                                           18    1135
XP_006726609                                                           17    4312
XP_006719787                                                           17    4312
XP_006710027                                                           17    4312
NP_079066                                                              15    9605
NP_001278268                                                           15    9605
NP_000731                                                              15    9605
NP_001014308                                                           15    9605
NP_001265410                                                           15    9605
NP_001265411                                                           15    9605
NP_001265409                                                           15    9605
NP_060039                                                              15    9605
XP_005266524                                                           15    9605
XP_005266523                                                           15    9605
XP_005266522                                                           15    9605
XP_005266521                                                           15    9605
XP_005266519                                                           15    9605
XP_005266518                                                           15    9605
XP_005266517                                                           15    9605
XP_005266515                                                           15    9605
XP_005266514                                                           15    9605
XP_005266512                                                           15    9605
XP_005266513                                                           15    9605
XP_005266511                                                           15    9605
XP_005266510                                                           15    9605
XP_005266509                                                           15    9605
XP_005266508                                                           15    9605
XP_005266507                                                           15    9605
XP_005266506                                                           15    9605
XP_005266505                                                           15    9605
XP_005266504                                                           15    9605
XP_006716540                                                           15    9605
XP_006716539                                                           15    9605
XP_006716538                                                           15    9605
XP_005251368                                                           15    9605
XP_006716537                                                           15    9605
XP_006716536                                                           15    9605
XP_005251364                                                           15    9605
XP_006716535                                                           15    9605
XP_006716534                                                           15    9605
XP_006716533                                                           15    9605
XP_006716532                                                           15    9605
XP_005251363                                                           15    9605
XP_005251362                                                           15    9605
XP_005273091                                                           15    9605
XP_005273090                                                           15    9605
XP_006711795                                                           15    9605
XP_005273089                                                           15    9605
>NP_443179
          Length = 2170

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VQQQSLSQ 9
            VQQQSLSQ
Sbjct: 1137 VQQQSLSQ 1144
>XP_005266703
          Length = 1501

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VQQQSLSQ 9
           VQQQSLSQ
Sbjct: 468 VQQQSLSQ 475
>XP_006726609
          Length = 2838

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    EVQQQSLSQ 9
            EV+Q++LSQ
Sbjct: 2351 EVEQKTLSQ 2359
>XP_006719787
          Length = 2838

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    EVQQQSLSQ 9
            EV+Q++LSQ
Sbjct: 2351 EVEQKTLSQ 2359
>XP_006710027
          Length = 2837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    EVQQQSLSQ 9
            EV+Q++LSQ
Sbjct: 2350 EVEQKTLSQ 2358
>NP_079066
          Length = 1221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 1007 EIQQQAL 1013
>NP_001278268
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EVQQQSL 7
           E+QQQ+L
Sbjct: 662 EIQQQAL 668
>NP_000731
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EVQQQSLSQ 9
           E+QQQS+ +
Sbjct: 294 ELQQQSMKR 302
>NP_001014308
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 638 QQQQLSQ 644
>NP_001265410
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 639 QQQQLSQ 645
>NP_001265411
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 639 QQQQLSQ 645
>NP_001265409
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 585 QQRSLSQ 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 717 QQQQLSQ 723
>NP_060039
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 639 QQQQLSQ 645
>XP_005266524
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 627 QQQQLSQ 633
>XP_005266523
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 638 QQQQLSQ 644
>XP_005266522
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 638 QQQQLSQ 644
>XP_005266521
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 627 QQQQLSQ 633
>XP_005266519
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 639 QQQQLSQ 645
>XP_005266518
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 586 QQRSLSQ 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 706 QQQQLSQ 712
>XP_005266517
          Length = 812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 586 QQRSLSQ 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 718 QQQQLSQ 724
>XP_005266515
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 573 QQRSLSQ 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 705 QQQQLSQ 711
>XP_005266514
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 573 QQRSLSQ 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 705 QQQQLSQ 711
>XP_005266512
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 586 QQRSLSQ 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 706 QQQQLSQ 712
>XP_005266513
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 574 QQRSLSQ 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 706 QQQQLSQ 712
>XP_005266511
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 574 QQRSLSQ 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 706 QQQQLSQ 712
>XP_005266510
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 585 QQRSLSQ 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 717 QQQQLSQ 723
>XP_005266509
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 585 QQRSLSQ 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 717 QQQQLSQ 723
>XP_005266508
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 585 QQRSLSQ 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 717 QQQQLSQ 723
>XP_005266507
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 586 QQRSLSQ 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 718 QQQQLSQ 724
>XP_005266506
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 586 QQRSLSQ 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 718 QQQQLSQ 724
>XP_005266505
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 586 QQRSLSQ 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 718 QQQQLSQ 724
>XP_005266504
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QQQSLSQ 9
           QQ+SLSQ
Sbjct: 586 QQRSLSQ 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QQQSLSQ 9
           QQQ LSQ
Sbjct: 718 QQQQLSQ 724
>XP_006716540
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EVQQQSL 7
           E+QQQ+L
Sbjct: 865 EIQQQAL 871
>XP_006716539
          Length = 1152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 1042 EIQQQAL 1048
>XP_006716538
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EVQQQSL 7
           E+QQQ+L
Sbjct: 956 EIQQQAL 962
>XP_005251368
          Length = 1185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EVQQQSL 7
           E+QQQ+L
Sbjct: 971 EIQQQAL 977
>XP_006716537
          Length = 1205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EVQQQSL 7
           E+QQQ+L
Sbjct: 991 EIQQQAL 997
>XP_006716536
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 998  EIQQQAL 1004
>XP_005251364
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 998  EIQQQAL 1004
>XP_006716535
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 1006 EIQQQAL 1012
>XP_006716534
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 1006 EIQQQAL 1012
>XP_006716533
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 1006 EIQQQAL 1012
>XP_006716532
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 1009 EIQQQAL 1015
>XP_005251363
          Length = 1248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 1034 EIQQQAL 1040
>XP_005251362
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    EVQQQSL 7
            E+QQQ+L
Sbjct: 1042 EIQQQAL 1048
>XP_005273091
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EVQQQSLSQ 9
           E+QQQS+ +
Sbjct: 294 ELQQQSMKR 302
>XP_005273090
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EVQQQSLSQ 9
           E+QQQS+ +
Sbjct: 294 ELQQQSMKR 302
>XP_006711795
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EVQQQSLSQ 9
           E+QQQS+ +
Sbjct: 294 ELQQQSMKR 302
>XP_005273089
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EVQQQSLSQ 9
           E+QQQS+ +
Sbjct: 294 ELQQQSMKR 302
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.287    0.100    0.209 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 376,591
Number of extensions: 501
Number of successful extensions: 64
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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