Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000242                                                              20     299
XP_005264389                                                           20     299
NP_004555                                                              19     869
XP_005263120                                                           19     869
NP_001186578                                                           17    4312
NP_722560                                                              17    4312
NP_005598                                                              17    4312
NP_005931                                                              17    4312
XP_005251071                                                           17    4312
XP_006716673                                                           17    4312
XP_005251070                                                           17    4312
XP_006716672                                                           17    4312
XP_005251069                                                           17    4312
XP_006716671                                                           17    4312
XP_005251068                                                           17    4312
XP_006716670                                                           17    4312
XP_005251067                                                           17    4312
XP_005251066                                                           17    4312
XP_005251065                                                           17    4312
XP_005251064                                                           17    4312
XP_006716669                                                           17    4312
XP_005251063                                                           17    4312
XP_005251062                                                           17    4312
XP_005251061                                                           17    4312
XP_005251060                                                           17    4312
NP_060222                                                              16    5631
XP_006724733                                                           16    5631
XP_006724732                                                           16    5631
NP_005753                                                              16    5631
NP_940870                                                              16    7355
XP_006715495                                                           16    7355
XP_006715494                                                           16    7355
XP_006715493                                                           16    7355
NP_001077430                                                           15    9605
NP_775907                                                              15    9605
NP_758424                                                              15    9605
NP_061142                                                              15    9605
NP_055453                                                              15    9605
NP_006065                                                              15    9605
NP_001186502                                                           15    9605
NP_067629                                                              15    9605
NP_001003827                                                           15    9605
NP_001271324                                                           15    9605
NP_001007526                                                           15    9605
NP_001277284                                                           15    9605
NP_001003819                                                           15    9605
NP_078800                                                              15    9605
NP_064597                                                              15    9605
XP_006725014                                                           15    9605
XP_006725013                                                           15    9605
XP_006725012                                                           15    9605
XP_005258866                                                           15    9605
XP_006720681                                                           15    9605
XP_006720680                                                           15    9605
XP_006720679                                                           15    9605
XP_006720678                                                           15    9605
XP_006720677                                                           15    9605
XP_006713805                                                           15    9605
XP_005269417                                                           15    9605
XP_005269415                                                           15    9605
XP_005269414                                                           15    9605
XP_006711118                                                           15    9605
XP_006711117                                                           15    9605
>NP_000242
          Length = 934

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  EVGLVRFFQ 9
          EVG VRFFQ
Sbjct: 16 EVGFVRFFQ 24
>XP_005264389
          Length = 921

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  EVGLVRFFQ 9
          EVG VRFFQ
Sbjct: 16 EVGFVRFFQ 24
>NP_004555
          Length = 557

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EVGLVRFFQ 9
           EVGL+ FFQ
Sbjct: 401 EVGLLEFFQ 409
>XP_005263120
          Length = 512

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EVGLVRFFQ 9
           EVGL+ FFQ
Sbjct: 401 EVGLLEFFQ 409
>NP_001186578
          Length = 1065

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 200 DVGLKRFF 207
>NP_722560
          Length = 1052

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 200 DVGLKRFF 207
>NP_005598
          Length = 1074

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 222 DVGLKRFF 229
>NP_005931
          Length = 488

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EVGLVRF 7
           E+GLVRF
Sbjct: 379 ELGLVRF 385
>XP_005251071
          Length = 955

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EVGLVRFF 8
          +VGL RFF
Sbjct: 87 DVGLKRFF 94
>XP_006716673
          Length = 983

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EVGLVRFF 8
          +VGL RFF
Sbjct: 87 DVGLKRFF 94
>XP_005251070
          Length = 983

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EVGLVRFF 8
          +VGL RFF
Sbjct: 87 DVGLKRFF 94
>XP_006716672
          Length = 983

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EVGLVRFF 8
          +VGL RFF
Sbjct: 87 DVGLKRFF 94
>XP_005251069
          Length = 1096

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 200 DVGLKRFF 207
>XP_006716671
          Length = 1096

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 200 DVGLKRFF 207
>XP_005251068
          Length = 1096

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>XP_006716670
          Length = 1099

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>XP_005251067
          Length = 1103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>XP_005251066
          Length = 1104

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>XP_005251065
          Length = 1105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>XP_005251064
          Length = 1106

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>XP_006716669
          Length = 1109

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 213 DVGLKRFF 220
>XP_005251063
          Length = 1112

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>XP_005251062
          Length = 1133

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>XP_005251061
          Length = 1137

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>XP_005251060
          Length = 1140

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           +VGL RFF
Sbjct: 244 DVGLKRFF 251
>NP_060222
          Length = 1120

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EVGLVRFFQ 9
            E  LVRFF+
Sbjct: 1089 EPALVRFFE 1097
>XP_006724733
          Length = 1022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EVGLVRFFQ 9
           E  LVRFF+
Sbjct: 991 EPALVRFFE 999
>XP_006724732
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EVGLVRFFQ 9
            E  LVRFF+
Sbjct: 1039 EPALVRFFE 1047
>NP_005753
          Length = 835

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGLVRFFQ 9
           +GL RFF+
Sbjct: 786 IGLQRFFE 793
>NP_940870
          Length = 1243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EVGLVRFF 8
           EVGL  FF
Sbjct: 525 EVGLQNFF 532
>XP_006715495
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EVGLVRFF 8
           EVGL  FF
Sbjct: 525 EVGLQNFF 532
>XP_006715494
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EVGLVRFF 8
           EVGL  FF
Sbjct: 299 EVGLQNFF 306
>XP_006715493
          Length = 1243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EVGLVRFF 8
           EVGL  FF
Sbjct: 525 EVGLQNFF 532
>NP_001077430
          Length = 1523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GLVRFFQ 9
           G+VR FQ
Sbjct: 315 GIVRIFQ 321
>NP_775907
          Length = 1518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GLVRFFQ 9
           G+VR FQ
Sbjct: 315 GIVRIFQ 321
>NP_758424
          Length = 1642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VGLVRFF 8
           VG+V FF
Sbjct: 327 VGIVEFF 333
>NP_061142
          Length = 1642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VGLVRFF 8
           VG+V FF
Sbjct: 327 VGIVEFF 333
>NP_055453
          Length = 1416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  GLVRFF 8
          GLVRF+
Sbjct: 64 GLVRFY 69
>NP_006065
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   EVGLVRFF 8
           E G+V FF
Sbjct: 450 EAGIVSFF 457
>NP_001186502
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   EVGLVRFF 8
           E G+V FF
Sbjct: 446 EAGIVSFF 453
>NP_067629
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   EVGLVRFF 8
           E G+V FF
Sbjct: 440 EAGIVSFF 447
>NP_001003827
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   EVGLVRFF 8
           E G+V FF
Sbjct: 440 EAGIVSFF 447
>NP_001271324
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G++R F
Sbjct: 164 EMGIIRLF 171
>NP_001007526
          Length = 1432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EVGLVR 6
           EVGLVR
Sbjct: 783 EVGLVR 788
>NP_001277284
          Length = 1429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EVGLVR 6
           EVGLVR
Sbjct: 648 EVGLVR 653
>NP_001003819
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   EVGLVRFF 8
           E G+V FF
Sbjct: 794 EAGIVSFF 801
>NP_078800
          Length = 1226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G+VR F
Sbjct: 619 EIGIVRQF 626
>NP_064597
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G++R F
Sbjct: 164 EMGIIRLF 171
>XP_006725014
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  GLVRFF 8
          GLVRF+
Sbjct: 37 GLVRFY 42
>XP_006725013
          Length = 1389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  GLVRFF 8
          GLVRF+
Sbjct: 37 GLVRFY 42
>XP_006725012
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  GLVRFF 8
          GLVRF+
Sbjct: 37 GLVRFY 42
>XP_005258866
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GLVRFFQ 9
           G+VR FQ
Sbjct: 315 GIVRIFQ 321
>XP_006720681
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G++R F
Sbjct: 164 EMGIIRLF 171
>XP_006720680
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G++R F
Sbjct: 164 EMGIIRLF 171
>XP_006720679
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G++R F
Sbjct: 164 EMGIIRLF 171
>XP_006720678
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G++R F
Sbjct: 164 EMGIIRLF 171
>XP_006720677
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G++R F
Sbjct: 164 EMGIIRLF 171
>XP_006713805
          Length = 1074

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G+VR F
Sbjct: 437 EIGIVRQF 444
>XP_005269417
          Length = 1104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G+VR F
Sbjct: 619 EIGIVRQF 626
>XP_005269415
          Length = 1229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G+VR F
Sbjct: 592 EIGIVRQF 599
>XP_005269414
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EVGLVRFF 8
           E+G+VR F
Sbjct: 619 EIGIVRQF 626
>XP_006711118
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  GLVRFF 8
          GLVRF+
Sbjct: 37 GLVRFY 42
>XP_006711117
          Length = 1413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  GLVRFF 8
          GLVRF+
Sbjct: 61 GLVRFY 66
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.160    0.469 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 492,097
Number of extensions: 1075
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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