Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1135
NP_001138390                                                           18    1135
NP_001138386                                                           18    1135
NP_001138387                                                           18    1135
NP_000132                                                              18    1135
NP_075259                                                              18    1135
NP_001138388                                                           18    1135
NP_001138391                                                           18    1135
NP_001138385                                                           18    1135
NP_075418                                                              18    1135
XP_006717776                                                           18    1135
XP_006717775                                                           18    1135
XP_006717774                                                           18    1135
XP_006717773                                                           18    1135
XP_006717772                                                           18    1135
XP_006717771                                                           18    1135
NP_001156685                                                           17    4312
NP_000133                                                              17    4312
NP_075254                                                              17    4312
XP_006713936                                                           17    4312
XP_006713935                                                           17    4312
XP_006713934                                                           17    4312
XP_006713933                                                           17    4312
XP_006713932                                                           17    4312
XP_006713931                                                           17    4312
NP_055798                                                              16    7355
XP_006714830                                                           16    7355
XP_006714829                                                           16    7355
XP_006714828                                                           16    7355
NP_000213                                                              15    9605
NP_001087241                                                           15    9605
NP_001161846                                                           15    9605
NP_001161849                                                           15    9605
NP_001161848                                                           15    9605
NP_001239257                                                           15    9605
NP_055624                                                              15    9605
NP_001161847                                                           15    9605
XP_006715351                                                           15    9605
XP_006715350                                                           15    9605
XP_006715349                                                           15    9605
XP_005249561                                                           15    9605
XP_005265799                                                           15    9605
XP_005265798                                                           15    9605
XP_005265797                                                           15    9605
>NP_001138389
          Length = 705

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 394 EAVTVAVKM 402
>NP_001138390
          Length = 704

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 393 EAVTVAVKM 401
>NP_001138386
          Length = 709

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 398 EAVTVAVKM 406
>NP_001138387
          Length = 707

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 421 EAVTVAVKM 429
>NP_000132
          Length = 821

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 510 EAVTVAVKM 518
>NP_075259
          Length = 822

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 511 EAVTVAVKM 519
>NP_001138388
          Length = 706

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 395 EAVTVAVKM 403
>NP_001138391
          Length = 680

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 422 EAVTVAVKM 430
>NP_001138385
          Length = 769

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 511 EAVTVAVKM 519
>NP_075418
          Length = 732

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 421 EAVTVAVKM 429
>XP_006717776
          Length = 806

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 529 EAVTVAVKM 537
>XP_006717775
          Length = 726

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 415 EAVTVAVKM 423
>XP_006717774
          Length = 752

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 441 EAVTVAVKM 449
>XP_006717773
          Length = 807

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 530 EAVTVAVKM 538
>XP_006717772
          Length = 838

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 527 EAVTVAVKM 535
>XP_006717771
          Length = 839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVTVAVKM 9
           E VTVAVKM
Sbjct: 528 EAVTVAVKM 536
>NP_001156685
          Length = 808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           VTVAVKM
Sbjct: 505 VTVAVKM 511
>NP_000133
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           VTVAVKM
Sbjct: 503 VTVAVKM 509
>NP_075254
          Length = 694

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           VTVAVKM
Sbjct: 391 VTVAVKM 397
>XP_006713936
          Length = 807

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           VTVAVKM
Sbjct: 503 VTVAVKM 509
>XP_006713935
          Length = 807

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           VTVAVKM
Sbjct: 504 VTVAVKM 510
>XP_006713934
          Length = 809

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           VTVAVKM
Sbjct: 505 VTVAVKM 511
>XP_006713933
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           VTVAVKM
Sbjct: 506 VTVAVKM 512
>XP_006713932
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           VTVAVKM
Sbjct: 507 VTVAVKM 513
>XP_006713931
          Length = 811

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           VTVAVKM
Sbjct: 507 VTVAVKM 513
>NP_055798
          Length = 1292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETVTVAVKM 9
           +TVT  VKM
Sbjct: 779 QTVTAQVKM 787
>XP_006714830
          Length = 1007

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETVTVAVKM 9
           +TVT  VKM
Sbjct: 494 QTVTAQVKM 502
>XP_006714829
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETVTVAVKM 9
           +TVT  VKM
Sbjct: 580 QTVTAQVKM 588
>XP_006714828
          Length = 1126

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETVTVAVKM 9
           +TVT  VKM
Sbjct: 613 QTVTAQVKM 621
>NP_000213
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           +TVAVKM
Sbjct: 618 MTVAVKM 624
>NP_001087241
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           +TVAVKM
Sbjct: 614 MTVAVKM 620
>NP_001161846
          Length = 1063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 697 TLTVAVK 703
>NP_001161849
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 706 TLTVAVK 712
>NP_001161848
          Length = 1027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 661 TLTVAVK 667
>NP_001239257
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 117 TLTVAVK 123
>NP_055624
          Length = 1072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 706 TLTVAVK 712
>NP_001161847
          Length = 1072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 706 TLTVAVK 712
>XP_006715351
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 554 TLTVAVK 560
>XP_006715350
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 768 TLTVAVK 774
>XP_006715349
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 735 TLTVAVK 741
>XP_005249561
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTVAVK 8
           T+TVAVK
Sbjct: 768 TLTVAVK 774
>XP_005265799
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           +TVAVKM
Sbjct: 615 MTVAVKM 621
>XP_005265798
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           +TVAVKM
Sbjct: 619 MTVAVKM 625
>XP_005265797
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VTVAVKM 9
           +TVAVKM
Sbjct: 619 MTVAVKM 625
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.116    0.264 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 227,589
Number of extensions: 184
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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