Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              18    1135
XP_005266703                                                           18    1135
NP_075573                                                              16    5631
NP_075571                                                              16    5631
NP_079490                                                              16    5631
NP_001137301                                                           16    5631
NP_001879                                                              16    5631
NP_001014444                                                           16    5631
XP_005266829                                                           16    5631
XP_006722615                                                           16    5631
NP_001554                                                              16    7355
NP_001269297                                                           16    7355
NP_060362                                                              16    7355
XP_005246736                                                           16    7355
XP_005246735                                                           16    7355
XP_005246734                                                           16    7355
XP_005246733                                                           16    7355
NP_001275707                                                           15    9605
NP_004415                                                              15    9605
NP_996531                                                              15    9605
XP_006720921                                                           15    9605
XP_006720920                                                           15    9605
XP_005255213                                                           15    9605
XP_005255212                                                           15    9605
XP_005254088                                                           15    9605
XP_006719978                                                           15    9605
XP_005254087                                                           15    9605
XP_005247366                                                           15    9605
XP_006713639                                                           15    9605
XP_005247365                                                           15    9605
XP_005247364                                                           15    9605
XP_005247363                                                           15    9605
XP_006713637                                                           15    9605
XP_006713636                                                           15    9605
XP_005247362                                                           15    9605
XP_005247360                                                           15    9605
XP_006713635                                                           15    9605
XP_006713634                                                           15    9605
XP_005247359                                                           15    9605
XP_005247358                                                           15    9605
XP_006713633                                                           15    9605
XP_005247357                                                           15    9605
XP_006713632                                                           15    9605
XP_005247356                                                           15    9605
XP_005247355                                                           15    9605
XP_005247354                                                           15    9605
XP_005247353                                                           15    9605
XP_005247352                                                           15    9605
XP_005247351                                                           15    9605
XP_005247350                                                           15    9605
XP_005247348                                                           15    9605
XP_005247347                                                           15    9605
XP_005247346                                                           15    9605
XP_005247345                                                           15    9605
XP_005247344                                                           15    9605
XP_005247343                                                           15    9605
XP_005247342                                                           15    9605
XP_005247341                                                           15    9605
XP_005247340                                                           15    9605
XP_005247339                                                           15    9605
XP_006713631                                                           15    9605
XP_005247338                                                           15    9605
>NP_443179
          Length = 2170

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    TVTIATEV 9
            TVTIATEV
Sbjct: 1010 TVTIATEV 1017
>XP_005266703
          Length = 1501

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TVTIATEV 9
           TVTIATEV
Sbjct: 341 TVTIATEV 348
>NP_075573
          Length = 517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVTIATEV 9
           TVTIAT +
Sbjct: 484 TVTIATRI 491
>NP_075571
          Length = 672

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVTIATEV 9
           TVTIAT +
Sbjct: 639 TVTIATRI 646
>NP_079490
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TVTIATEV 9
          TVT+ TE+
Sbjct: 3  TVTVTTEI 10
>NP_001137301
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TVTIATEV 9
          TVT+ TE+
Sbjct: 3  TVTVTTEI 10
>NP_001879
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTIATE 8
           TVT+ATE
Sbjct: 203 TVTLATE 209
>NP_001014444
          Length = 272

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTIATE 8
           TVT+ATE
Sbjct: 161 TVTLATE 167
>XP_005266829
          Length = 288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TVTIATEV 9
          TVT+ TE+
Sbjct: 3  TVTVTTEI 10
>XP_006722615
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TVTIATEV 9
          TVT+ TE+
Sbjct: 3  TVTVTTEI 10
>NP_001554
          Length = 797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETVTIATEV 9
           ET+ I+T+V
Sbjct: 181 ETIVISTDV 189
>NP_001269297
          Length = 719

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETVTIATEV 9
           ET+ I+T+V
Sbjct: 103 ETIVISTDV 111
>NP_060362
          Length = 930

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTIATE 8
           TVTI+TE
Sbjct: 304 TVTISTE 310
>XP_005246736
          Length = 976

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTIATE 8
           TVTI+TE
Sbjct: 346 TVTISTE 352
>XP_005246735
          Length = 976

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTIATE 8
           TVTI+TE
Sbjct: 346 TVTISTE 352
>XP_005246734
          Length = 934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTIATE 8
           TVTI+TE
Sbjct: 304 TVTISTE 310
>XP_005246733
          Length = 972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVTIATE 8
           TVTI+TE
Sbjct: 346 TVTISTE 352
>NP_001275707
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVTIAT 7
           +T+TIAT
Sbjct: 532 DTITIAT 538
>NP_004415
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVTIAT 7
           +T+TIAT
Sbjct: 709 DTITIAT 715
>NP_996531
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TVTIATEV 9
           TVT+AT +
Sbjct: 330 TVTLATSI 337
>XP_006720921
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVTIAT 7
           +T+TIAT
Sbjct: 708 DTITIAT 714
>XP_006720920
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVTIAT 7
           +T+TIAT
Sbjct: 710 DTITIAT 716
>XP_005255213
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVTIAT 7
           +T+TIAT
Sbjct: 761 DTITIAT 767
>XP_005255212
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVTIAT 7
           +T+TIAT
Sbjct: 762 DTITIAT 768
>XP_005254088
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TVTIATEV 9
           TVT+AT +
Sbjct: 296 TVTLATSI 303
>XP_006719978
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TVTIATEV 9
           TVT+AT +
Sbjct: 330 TVTLATSI 337
>XP_005254087
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TVTIATEV 9
           TVT+AT +
Sbjct: 330 TVTLATSI 337
>XP_005247366
          Length = 1495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ETVTIATE 8
           E+VT++TE
Sbjct: 836 ESVTLSTE 843
>XP_006713639
          Length = 1579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ETVTIATE 8
           E+VT++TE
Sbjct: 920 ESVTLSTE 927
>XP_005247365
          Length = 1607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ETVTIATE 8
           E+VT++TE
Sbjct: 948 ESVTLSTE 955
>XP_005247364
          Length = 1637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ETVTIATE 8
           E+VT++TE
Sbjct: 978 ESVTLSTE 985
>XP_005247363
          Length = 1657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 998  ESVTLSTE 1005
>XP_006713637
          Length = 1659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1000 ESVTLSTE 1007
>XP_006713636
          Length = 1673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1014 ESVTLSTE 1021
>XP_005247362
          Length = 1678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1019 ESVTLSTE 1026
>XP_005247360
          Length = 1706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1047 ESVTLSTE 1054
>XP_006713635
          Length = 1719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1060 ESVTLSTE 1067
>XP_006713634
          Length = 1721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1062 ESVTLSTE 1069
>XP_005247359
          Length = 1725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1066 ESVTLSTE 1073
>XP_005247358
          Length = 1726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1134 ESVTLSTE 1141
>XP_006713633
          Length = 1731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1072 ESVTLSTE 1079
>XP_005247357
          Length = 1735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1076 ESVTLSTE 1083
>XP_006713632
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1134 ESVTLSTE 1141
>XP_005247356
          Length = 1744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1085 ESVTLSTE 1092
>XP_005247355
          Length = 1745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1086 ESVTLSTE 1093
>XP_005247354
          Length = 1745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1086 ESVTLSTE 1093
>XP_005247353
          Length = 1746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1087 ESVTLSTE 1094
>XP_005247352
          Length = 1747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1088 ESVTLSTE 1095
>XP_005247351
          Length = 1754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1095 ESVTLSTE 1102
>XP_005247350
          Length = 1757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1134 ESVTLSTE 1141
>XP_005247348
          Length = 1767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1134 ESVTLSTE 1141
>XP_005247347
          Length = 1768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1134 ESVTLSTE 1141
>XP_005247346
          Length = 1768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1109 ESVTLSTE 1116
>XP_005247345
          Length = 1769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1110 ESVTLSTE 1117
>XP_005247344
          Length = 1771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1134 ESVTLSTE 1141
>XP_005247343
          Length = 1771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1112 ESVTLSTE 1119
>XP_005247342
          Length = 1773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1114 ESVTLSTE 1121
>XP_005247341
          Length = 1774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1115 ESVTLSTE 1122
>XP_005247340
          Length = 1777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1134 ESVTLSTE 1141
>XP_005247339
          Length = 1779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1120 ESVTLSTE 1127
>XP_006713631
          Length = 1789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1130 ESVTLSTE 1137
>XP_005247338
          Length = 1793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ETVTIATE 8
            E+VT++TE
Sbjct: 1134 ESVTLSTE 1141
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.113    0.255 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 306,493
Number of extensions: 461
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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