Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245200                                                           19     665
NP_000240                                                              19     665
XP_005265218                                                           19     665
NP_001164100                                                           15    9605
NP_065971                                                              15    9605
NP_001276988                                                           15    9605
NP_001025181                                                           15    9605
NP_001154945                                                           15    9605
NP_000685                                                              15    9605
NP_055592                                                              15    9605
NP_056445                                                              15    9605
NP_055590                                                              15    9605
NP_001007468                                                           15    9605
NP_001245256                                                           15    9605
NP_001245255                                                           15    9605
NP_001245254                                                           15    9605
NP_002724                                                              15    9605
NP_001026786                                                           15    9605
NP_001193639                                                           15    9605
XP_006724453                                                           15    9605
XP_005261930                                                           15    9605
XP_006724452                                                           15    9605
XP_005261929                                                           15    9605
XP_005261928                                                           15    9605
XP_005261927                                                           15    9605
XP_006724451                                                           15    9605
XP_005261926                                                           15    9605
XP_005261925                                                           15    9605
XP_005269077                                                           15    9605
XP_006719563                                                           15    9605
XP_006719562                                                           15    9605
XP_005269076                                                           15    9605
XP_006712474                                                           15    9605
XP_005273417                                                           15    9605
NP_001193638                                                           15    9605
NP_000686                                                              15    9605
>NP_001245200
          Length = 687

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  ETVLNRIAA 9
          ETV+NRIAA
Sbjct: 13 ETVVNRIAA 21
>NP_000240
          Length = 756

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  ETVLNRIAA 9
          ETV+NRIAA
Sbjct: 13 ETVVNRIAA 21
>XP_005265218
          Length = 687

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  ETVLNRIAA 9
          ETV+NRIAA
Sbjct: 13 ETVVNRIAA 21
>NP_001164100
          Length = 2581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    ETVLNRI 7
            ETV NR+
Sbjct: 2399 ETVFNRV 2405
>NP_065971
          Length = 2302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    ETVLNRI 7
            ETV NR+
Sbjct: 2120 ETVFNRV 2126
>NP_001276988
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  ETVLNRIA 8
          +TV NR+A
Sbjct: 30 QTVANRVA 37
>NP_001025181
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ETVLNRIA 8
           +TV NR+A
Sbjct: 189 QTVANRVA 196
>NP_001154945
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ETVLNRIA 8
           +TV NR+A
Sbjct: 226 QTVANRVA 233
>NP_000685
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ETVLNRIA 8
           +TV NR+A
Sbjct: 226 QTVANRVA 233
>NP_055592
          Length = 1524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           +TVLNR+
Sbjct: 279 DTVLNRL 285
>NP_056445
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           ET+LNR+
Sbjct: 122 ETLLNRL 128
>NP_055590
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 928 LLNRIAA 934
>NP_001007468
          Length = 1242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 959 LLNRIAA 965
>NP_001245256
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 865 LLNRIAA 871
>NP_001245255
          Length = 1160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 877 LLNRIAA 883
>NP_001245254
          Length = 1187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 904 LLNRIAA 910
>NP_002724
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           ET++NR+
Sbjct: 286 ETIINRL 292
>NP_001026786
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ETVLNRIA 8
           +TV NR+A
Sbjct: 145 QTVANRVA 152
>NP_001193639
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           ET++NR+
Sbjct: 254 ETIINRL 260
>XP_006724453
          Length = 1160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 877 LLNRIAA 883
>XP_005261930
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 877 LLNRIAA 883
>XP_006724452
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 877 LLNRIAA 883
>XP_005261929
          Length = 1240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 928 LLNRIAA 934
>XP_005261928
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 935 LLNRIAA 941
>XP_005261927
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 935 LLNRIAA 941
>XP_006724451
          Length = 1271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 959 LLNRIAA 965
>XP_005261926
          Length = 1271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 959 LLNRIAA 965
>XP_005261925
          Length = 1271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLNRIAA 9
           +LNRIAA
Sbjct: 959 LLNRIAA 965
>XP_005269077
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           ET++NR+
Sbjct: 202 ETIINRL 208
>XP_006719563
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           ET++NR+
Sbjct: 235 ETIINRL 241
>XP_006719562
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           ET++NR+
Sbjct: 254 ETIINRL 260
>XP_005269076
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           ET++NR+
Sbjct: 323 ETIINRL 329
>XP_006712474
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ETVLNRI 7
          ET+LNR+
Sbjct: 6  ETLLNRL 12
>XP_005273417
          Length = 1487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           +TVLNR+
Sbjct: 279 DTVLNRL 285
>NP_001193638
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   ETVLNRI 7
           ET++NR+
Sbjct: 295 ETIINRL 301
>NP_000686
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ETVLNRIA 8
           +TV NR+A
Sbjct: 145 QTVANRVA 152
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.127    0.304 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 293,509
Number of extensions: 459
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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