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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055726                                                              18    1935
NP_003310                                                              16    5631
NP_597676                                                              16    5631
NP_001243779                                                           16    5631
NP_596869                                                              16    5631
NP_659419                                                              16    5631
NP_004524                                                              16    5631
XP_005246888                                                           16    5631
XP_006712788                                                           16    5631
XP_006712787                                                           16    5631
XP_006712786                                                           16    5631
NP_001254479                                                           16    5631
NP_597681                                                              16    5631
NP_054706                                                              16    7355
NP_003364                                                              16    7355
XP_005270200                                                           16    7355
XP_005270199                                                           16    7355
NP_006824                                                              16    7355
NP_055196                                                              15    9605
NP_001035197                                                           15    9605
NP_689914                                                              15    9605
NP_002068                                                              15    9605
NP_001240766                                                           15    9605
XP_005267591                                                           15    9605
XP_005267590                                                           15    9605
XP_005267589                                                           15    9605
XP_005267588                                                           15    9605
XP_006720179                                                           15    9605
XP_006717126                                                           15    9605
XP_005251986                                                           15    9605
XP_006717125                                                           15    9605
XP_005263038                                                           15    9605
NP_859077                                                              15    9605

>NP_055726
          Length = 961

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETVKASEAA 9
           E VKASEAA
Sbjct: 335 EPVKASEAA 343



>NP_003310
          Length = 26926

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 14460 EPVKASEA 14467



>NP_597676
          Length = 27051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 14585 EPVKASEA 14592



>NP_001243779
          Length = 34350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 21884 EPVKASEA 21891



>NP_596869
          Length = 33423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 20957 EPVKASEA 20964



>NP_659419
          Length = 1989

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ETVKASEAA 9
            ETV+A EAA
Sbjct: 1763 ETVEAYEAA 1771



>NP_004524
          Length = 1141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TVKASEAA 9
           TVKASE A
Sbjct: 449 TVKASEQA 456



>XP_005246888
          Length = 22663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 10197 EPVKASEA 10204



>XP_006712788
          Length = 24022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 11556 EPVKASEA 11563



>XP_006712787
          Length = 33978

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 21512 EPVKASEA 21519



>XP_006712786
          Length = 35484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 23018 EPVKASEA 23025



>NP_001254479
          Length = 35991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 23525 EPVKASEA 23532



>NP_597681
          Length = 27118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     ETVKASEA 8
             E VKASEA
Sbjct: 14652 EPVKASEA 14659



>NP_054706
          Length = 1134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ETVKASEAA 9
            ETV+ +EAA
Sbjct: 1104 ETVREAEAA 1112



>NP_003364
          Length = 1066

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ETVKASEAA 9
            ETV+ +EAA
Sbjct: 1036 ETVREAEAA 1044



>XP_005270200
          Length = 1067

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ETVKASEAA 9
            ETV+ +EAA
Sbjct: 1037 ETVREAEAA 1045



>XP_005270199
          Length = 1135

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ETVKASEAA 9
            ETV+ +EAA
Sbjct: 1105 ETVREAEAA 1113



>NP_006824
          Length = 327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETVKASEA 8
           E VKASEA
Sbjct: 240 EYVKASEA 247



>NP_055196
          Length = 1429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETVKASEA 8
           ET+ ASEA
Sbjct: 474 ETIVASEA 481



>NP_001035197
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETVKASEA 8
           ET+ ASEA
Sbjct: 474 ETIVASEA 481



>NP_689914
          Length = 5058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ETVKASEA 8
            +TVK SEA
Sbjct: 2919 QTVKPSEA 2926



>NP_002068
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKASEAA 9
           T+KA EAA
Sbjct: 554 TLKAEEAA 561



>NP_001240766
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  TVKASEAA 9
          +VKASEA+
Sbjct: 19 SVKASEAS 26



>XP_005267591
          Length = 1275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETVKASEA 8
           ET+ ASEA
Sbjct: 474 ETIVASEA 481



>XP_005267590
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETVKASEA 8
           ET+ ASEA
Sbjct: 474 ETIVASEA 481



>XP_005267589
          Length = 1418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETVKASEA 8
           ET+ ASEA
Sbjct: 474 ETIVASEA 481



>XP_005267588
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETVKASEA 8
           ET+ ASEA
Sbjct: 474 ETIVASEA 481



>XP_006720179
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ETVKASEA 8
           ET+ ASEA
Sbjct: 474 ETIVASEA 481



>XP_006717126
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKASEAA 9
           T+KA EAA
Sbjct: 554 TLKAEEAA 561



>XP_005251986
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKASEAA 9
           T+KA EAA
Sbjct: 554 TLKAEEAA 561



>XP_006717125
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKASEAA 9
           T+KA EAA
Sbjct: 554 TLKAEEAA 561



>XP_005263038
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVKASE 7
           +T+KASE
Sbjct: 123 QTIKASE 129



>NP_859077
          Length = 158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ETVKASE 7
           +T+KASE
Sbjct: 123 QTIKASE 129



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.278   0.0913    0.190 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 189,762
Number of extensions: 154
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)