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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           18    1482
NP_000242                                                              18    1482
XP_005264389                                                           18    1482
NP_055325                                                              17    3301
NP_149015                                                              17    3301
XP_006715989                                                           17    3301
NP_056315                                                              16    5631
XP_005261163                                                           16    5631
NP_001159923                                                           16    7355
NP_000884                                                              16    7355
NP_061897                                                              16    7355
XP_005264436                                                           16    7355
XP_006712098                                                           16    7355
XP_006712097                                                           16    7355
NP_001136272                                                           15    9605
NP_001020419                                                           15    9605

>NP_001245210
          Length = 868

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETTSILRSA 9
           ET SILRSA
Sbjct: 665 ETASILRSA 673



>NP_000242
          Length = 934

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETTSILRSA 9
           ET SILRSA
Sbjct: 731 ETASILRSA 739



>XP_005264389
          Length = 921

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETTSILRSA 9
           ET SILRSA
Sbjct: 731 ETASILRSA 739



>NP_055325
          Length = 4935

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ETTSILRS 8
            ETT++LRS
Sbjct: 2463 ETTAVLRS 2470



>NP_149015
          Length = 5142

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ETTSILRS 8
            ETT++LRS
Sbjct: 2463 ETTAVLRS 2470



>XP_006715989
          Length = 5148

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ETTSILRS 8
            ETT++LRS
Sbjct: 2463 ETTAVLRS 2470



>NP_056315
          Length = 696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETTSILRSA 9
           E +S+LRSA
Sbjct: 115 EVSSVLRSA 123



>XP_005261163
          Length = 614

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ETTSILRSA 9
          E +S+LRSA
Sbjct: 33 EVSSVLRSA 41



>NP_001159923
          Length = 391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETTSILRS 8
           ETTS LRS
Sbjct: 363 ETTSHLRS 370



>NP_000884
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETTSILRS 8
           ETTS LRS
Sbjct: 399 ETTSHLRS 406



>NP_061897
          Length = 2071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TTSILRS 8
           TTS+LRS
Sbjct: 710 TTSLLRS 716



>XP_005264436
          Length = 1881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TTSILRS 8
           TTS+LRS
Sbjct: 710 TTSLLRS 716



>XP_006712098
          Length = 2059

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TTSILRS 8
           TTS+LRS
Sbjct: 698 TTSLLRS 704



>XP_006712097
          Length = 2070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TTSILRS 8
           TTS+LRS
Sbjct: 710 TTSLLRS 716



>NP_001136272
          Length = 3144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TTSILRS 8
            TTS++RS
Sbjct: 1424 TTSVIRS 1430



>NP_001020419
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TSILRSA 9
          TS+LRSA
Sbjct: 16 TSLLRSA 22



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.109    0.242 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 289,151
Number of extensions: 290
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)