Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_789765                                                              20     390
NP_001123914                                                           20     390
NP_005334                                                              20     390
NP_004976                                                              20     390
NP_002515                                                              20     390
NP_853510                                                              20     390
XP_006725199                                                           20     390
XP_006718280                                                           20     390
NP_203524                                                              18    1935
XP_006719132                                                           18    1935
NP_057613                                                              17    3301
NP_006086                                                              17    3301
NP_001098999                                                           17    3301
XP_006719899                                                           17    3301
XP_006719898                                                           17    3301
XP_006719897                                                           17    3301
XP_006719896                                                           17    3301
XP_005266476                                                           17    3301
XP_006714052                                                           17    3301
XP_005248100                                                           17    3301
NP_060918                                                              17    3301
NP_001120965                                                           16    5631
NP_066187                                                              16    5631
NP_001139                                                              16    5631
XP_006714257                                                           16    5631
XP_006714256                                                           16    5631
XP_006714255                                                           16    5631
XP_005263005                                                           16    5631
XP_006714254                                                           16    5631
XP_006714253                                                           16    5631
XP_005263002                                                           16    5631
XP_005262999                                                           16    5631
XP_006714252                                                           16    5631
XP_006714251                                                           16    5631
XP_006714250                                                           16    5631
NP_005393                                                              16    7355
NP_002872                                                              16    7355
XP_006715826                                                           16    7355
XP_006715825                                                           16    7355
XP_005263786                                                           16    7355
XP_005263785                                                           16    7355
XP_005263784                                                           16    7355
XP_005263781                                                           16    7355
NP_000207                                                              15    9605
NP_001138501                                                           15    9605
NP_005264                                                              15    9605
NP_064502                                                              15    9605
NP_001361                                                              15    9605
XP_006722388                                                           15    9605
XP_006712019                                                           15    9605
>NP_789765
          Length = 170

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ETS KTRQG
Sbjct: 143 ETSAKTRQG 151
>NP_001123914
          Length = 189

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ETS KTRQG
Sbjct: 143 ETSAKTRQG 151
>NP_005334
          Length = 189

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ETS KTRQG
Sbjct: 143 ETSAKTRQG 151
>NP_004976
          Length = 188

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ETS KTRQG
Sbjct: 143 ETSAKTRQG 151
>NP_002515
          Length = 189

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ETS KTRQG
Sbjct: 143 ETSAKTRQG 151
>NP_853510
          Length = 233

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ETS KTRQG
Sbjct: 179 ETSAKTRQG 187
>XP_006725199
          Length = 170

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ETS KTRQG
Sbjct: 143 ETSAKTRQG 151
>XP_006718280
          Length = 170

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ETS KTRQG
Sbjct: 143 ETSAKTRQG 151
>NP_203524
          Length = 189

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETSVKTRQ 8
           ETS KTRQ
Sbjct: 143 ETSAKTRQ 150
>XP_006719132
          Length = 189

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETSVKTRQ 8
           ETS KTRQ
Sbjct: 143 ETSAKTRQ 150
>NP_057613
          Length = 1188

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++K RQG
Sbjct: 210 ETNLKIRQG 218
>NP_006086
          Length = 1164

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++K RQG
Sbjct: 191 ETNLKIRQG 199
>NP_001098999
          Length = 1149

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++K RQG
Sbjct: 191 ETNLKIRQG 199
>XP_006719899
          Length = 677

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++K RQG
Sbjct: 170 ETNLKIRQG 178
>XP_006719898
          Length = 763

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++K RQG
Sbjct: 170 ETNLKIRQG 178
>XP_006719897
          Length = 1148

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++K RQG
Sbjct: 170 ETNLKIRQG 178
>XP_006719896
          Length = 1005

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ETSVKTRQG 9
          ET++K RQG
Sbjct: 27 ETNLKIRQG 35
>XP_005266476
          Length = 1148

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++K RQG
Sbjct: 170 ETNLKIRQG 178
>XP_006714052
          Length = 1000

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ETSVKTRQG 9
          ET++K RQG
Sbjct: 27 ETNLKIRQG 35
>XP_005248100
          Length = 1164

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++K RQG
Sbjct: 191 ETNLKIRQG 199
>NP_060918
          Length = 1230

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETSVKTRQ 8
           E SVKTRQ
Sbjct: 445 EKSVKTRQ 452
>NP_001120965
          Length = 1863

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 633 ETNIVTKQG 641
>NP_066187
          Length = 1872

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 654 ETNIVTKQG 662
>NP_001139
          Length = 3957

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 654 ETNIVTKQG 662
>XP_006714257
          Length = 4145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 678 ETNIVTKQG 686
>XP_006714256
          Length = 1901

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 686 ETNIVTKQG 694
>XP_006714255
          Length = 1970

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 686 ETNIVTKQG 694
>XP_005263005
          Length = 2019

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 686 ETNIVTKQG 694
>XP_006714254
          Length = 2049

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 686 ETNIVTKQG 694
>XP_006714253
          Length = 2069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 686 ETNIVTKQG 694
>XP_005263002
          Length = 4072

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 654 ETNIVTKQG 662
>XP_005262999
          Length = 4147

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 686 ETNIVTKQG 694
>XP_006714252
          Length = 4153

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 686 ETNIVTKQG 694
>XP_006714251
          Length = 4165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 686 ETNIVTKQG 694
>XP_006714250
          Length = 4190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ETSVKTRQG 9
           ET++ T+QG
Sbjct: 678 ETNIVTKQG 686
>NP_005393
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ETSVKTR 7
           ETS KTR
Sbjct: 155 ETSAKTR 161
>NP_002872
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ETSVKTR 7
           ETS KTR
Sbjct: 156 ETSAKTR 162
>XP_006715826
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ETSVKTR 7
           ETS KTR
Sbjct: 155 ETSAKTR 161
>XP_006715825
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ETSVKTR 7
           ETS KTR
Sbjct: 155 ETSAKTR 161
>XP_005263786
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ETSVKTR 7
           ETS KTR
Sbjct: 156 ETSAKTR 162
>XP_005263785
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ETSVKTR 7
           ETS KTR
Sbjct: 156 ETSAKTR 162
>XP_005263784
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ETSVKTR 7
           ETS KTR
Sbjct: 156 ETSAKTR 162
>XP_005263781
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ETSVKTR 7
           ETS KTR
Sbjct: 178 ETSAKTR 184
>NP_000207
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ETSVKTRQG 9
           E  VKTR+G
Sbjct: 404 EQLVKTRKG 412
>NP_001138501
          Length = 1392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ETSVKT 6
           ETSVKT
Sbjct: 367 ETSVKT 372
>NP_005264
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SVKTRQG 9
           S+KTR+G
Sbjct: 125 SLKTREG 131
>NP_064502
          Length = 1176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ETSVKT 6
           ETSVKT
Sbjct: 126 ETSVKT 131
>NP_001361
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ETSVKT 6
            ETSVKT
Sbjct: 3331 ETSVKT 3336
>XP_006722388
          Length = 1511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ETSVKT 6
           ETSVKT
Sbjct: 367 ETSVKT 372
>XP_006712019
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ETSVKT 6
            ETSVKT
Sbjct: 3331 ETSVKT 3336
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.110    0.268 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 349,595
Number of extensions: 443
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package