Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           18    1935
NP_858045                                                              18    1935
NP_006525                                                              18    1935
NP_001167559                                                           18    1935
XP_006726566                                                           15    9605
XP_005255523                                                           15    9605
XP_006717411                                                           15    9605
XP_006710279                                                           15    9605
NP_973729                                                              15    9605
NP_005613                                                              15    9605
>NP_001167558
          Length = 1423

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TSLLSTLS 9
           TSLLSTLS
Sbjct: 535 TSLLSTLS 542
>NP_858045
          Length = 1424

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TSLLSTLS 9
           TSLLSTLS
Sbjct: 535 TSLLSTLS 542
>NP_006525
          Length = 1420

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TSLLSTLS 9
           TSLLSTLS
Sbjct: 535 TSLLSTLS 542
>NP_001167559
          Length = 1415

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TSLLSTLS 9
           TSLLSTLS
Sbjct: 545 TSLLSTLS 552
>XP_006726566
          Length = 963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ETSLLSTLS 9
           E SLL TLS
Sbjct: 654 EESLLRTLS 662
>XP_005255523
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TSLLSTLS 9
           TS+L TLS
Sbjct: 309 TSILQTLS 316
>XP_006717411
          Length = 963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ETSLLSTLS 9
           E SLL TLS
Sbjct: 654 EESLLRTLS 662
>XP_006710279
          Length = 963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ETSLLSTLS 9
           E SLL TLS
Sbjct: 654 EESLLRTLS 662
>NP_973729
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TSLLSTLS 9
           TS+L TLS
Sbjct: 309 TSILQTLS 316
>NP_005613
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TSLLSTLS 9
           TS+L TLS
Sbjct: 309 TSILQTLS 316
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.291    0.106    0.224 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 269,439
Number of extensions: 398
Number of successful extensions: 10
Number of sequences better than 10000.0: 10
Number of HSP's gapped: 10
Number of HSP's successfully gapped: 10
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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