Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1935
NP_001185763                                                           18    1935
NP_055459                                                              18    1935
XP_006726410                                                           18    1935
XP_006711719                                                           18    1935
XP_006711718                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711712                                                           18    1935
XP_006711711                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
XP_005277503                                                           18    1935
XP_005273038                                                           18    1935
XP_006711708                                                           18    1935
XP_005277500                                                           18    1935
XP_006711707                                                           18    1935
XP_005277499                                                           18    1935
XP_006711706                                                           18    1935
XP_006711705                                                           18    1935
XP_006711164                                                           18    1935
XP_006710143                                                           18    1935
XP_006710142                                                           18    1935
XP_006710141                                                           18    1935
NP_001130                                                              16    5631
NP_006452                                                              16    7355
NP_060597                                                              15    9605
NP_001159434                                                           15    9605
NP_776065                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1188 EKLLLSEAT 1196
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1232 EKLLLSEAT 1240
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1232 EKLLLSEAT 1240
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1035 EKLLLSEAT 1043
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1188 EKLLLSEAT 1196
>XP_006711718
          Length = 1436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETLLLSEAT 9
           E LLLSEAT
Sbjct: 239 EKLLLSEAT 247
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1188 EKLLLSEAT 1196
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1298 EKLLLSEAT 1306
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1232 EKLLLSEAT 1240
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1232 EKLLLSEAT 1240
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1235 EKLLLSEAT 1243
>XP_006711712
          Length = 2473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1395 EKLLLSEAT 1403
>XP_006711711
          Length = 2482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1285 EKLLLSEAT 1293
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1298 EKLLLSEAT 1306
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1298 EKLLLSEAT 1306
>XP_005277503
          Length = 2498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1395 EKLLLSEAT 1403
>XP_005273038
          Length = 2509

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1395 EKLLLSEAT 1403
>XP_006711708
          Length = 2512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1395 EKLLLSEAT 1403
>XP_005277500
          Length = 2525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1395 EKLLLSEAT 1403
>XP_006711707
          Length = 2553

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1395 EKLLLSEAT 1403
>XP_005277499
          Length = 2561

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1395 EKLLLSEAT 1403
>XP_006711706
          Length = 2591

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1395 EKLLLSEAT 1403
>XP_006711705
          Length = 2592

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1395 EKLLLSEAT 1403
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ETLLLSEAT 9
            E LLLSEAT
Sbjct: 1035 EKLLLSEAT 1043
>XP_006710143
          Length = 562

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ETLLLSEAT 9
          E LLLSEAT
Sbjct: 74 EKLLLSEAT 82
>XP_006710142
          Length = 671

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETLLLSEAT 9
           E LLLSEAT
Sbjct: 184 EKLLLSEAT 192
>XP_006710141
          Length = 672

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ETLLLSEAT 9
           E LLLSEAT
Sbjct: 184 EKLLLSEAT 192
>NP_001130
          Length = 701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ETLLLSEAT 9
           ETL L EAT
Sbjct: 109 ETLALREAT 117
>NP_006452
          Length = 1193

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ETLLLSEA 8
           ETLLLS A
Sbjct: 899 ETLLLSTA 906
>NP_060597
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TLLLSEAT 9
           TLL+ EAT
Sbjct: 681 TLLIHEAT 688
>NP_001159434
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TLLLSEAT 9
           TLL+ EAT
Sbjct: 641 TLLIHEAT 648
>NP_776065
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TLLLSEAT 9
           TLL+ EAT
Sbjct: 680 TLLIHEAT 687
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.115    0.254 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 308,823
Number of extensions: 402
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package