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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_001035194                                                           17    2528
NP_001175                                                              16    5631
NP_001164352                                                           16    5631
NP_001164351                                                           16    5631
XP_006710300                                                           16    5631
XP_005247723                                                           16    7355
NP_001273148                                                           15    9605
NP_001185744                                                           15    9605
NP_065076                                                              15    9605
NP_005952                                                              15    9605
NP_443139                                                              15    9605
XP_005275558                                                           15    9605
XP_005275391                                                           15    9605
XP_005275259                                                           15    9605
XP_005274965                                                           15    9605
XP_005272815                                                           15    9605
XP_005274885                                                           15    9605
XP_006723662                                                           15    9605
XP_005260825                                                           15    9605
XP_006723661                                                           15    9605
XP_006719284                                                           15    9605
XP_006719283                                                           15    9605
XP_006719282                                                           15    9605
XP_005248836                                                           15    9605

>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ESTSMSTT 8
           ESTSMSTT
Sbjct: 408 ESTSMSTT 415



>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ESTSMSTT 8
           ESTSMSTT
Sbjct: 203 ESTSMSTT 210



>NP_001035194
          Length = 4493

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESTSMSTTL 9
           ESTS STTL
Sbjct: 120 ESTSDSTTL 128




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           E+TS STT
Sbjct: 665 EATSSSTT 672



>NP_001175
          Length = 2644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ESTSMSTTL 9
            EST + TTL
Sbjct: 1277 ESTDLQTTL 1285



>NP_001164352
          Length = 346

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ESTSMSTTL 9
           ESTSMS +L
Sbjct: 291 ESTSMSGSL 299



>NP_001164351
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ESTSMSTTL 9
           ESTSMS +L
Sbjct: 341 ESTSMSGSL 349



>XP_006710300
          Length = 1116

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           ESTS STT
Sbjct: 801 ESTSHSTT 808



>XP_005247723
          Length = 1481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   STSMSTT 8
           +TSMSTT
Sbjct: 581 NTSMSTT 587



>NP_001273148
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           EST+ STT
Sbjct: 354 ESTNKSTT 361



>NP_001185744
          Length = 1773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           E+TS STT
Sbjct: 864 ETTSASTT 871




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ESTSMSTT 8
            E+TS STT
Sbjct: 1003 ETTSASTT 1010



>NP_065076
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESTSMSTTL 9
           EST+  TTL
Sbjct: 845 ESTNSDTTL 853



>NP_005952
          Length = 2439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ESTSMSTT 8
            E+TS STT
Sbjct: 1705 EATSTSTT 1712



>NP_443139
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           EST+ STT
Sbjct: 842 ESTNKSTT 849



>XP_005275558
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           E+TS STT
Sbjct: 867 ETTSASTT 874




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ESTSMSTT 8
            E+TS STT
Sbjct: 1006 ETTSASTT 1013



>XP_005275391
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           E+TS STT
Sbjct: 867 ETTSASTT 874




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ESTSMSTT 8
            E+TS STT
Sbjct: 1006 ETTSASTT 1013



>XP_005275259
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           E+TS STT
Sbjct: 867 ETTSASTT 874




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ESTSMSTT 8
            E+TS STT
Sbjct: 1006 ETTSASTT 1013



>XP_005274965
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           E+TS STT
Sbjct: 867 ETTSASTT 874




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ESTSMSTT 8
            E+TS STT
Sbjct: 1006 ETTSASTT 1013



>XP_005272815
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           E+TS STT
Sbjct: 867 ETTSASTT 874




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ESTSMSTT 8
            E+TS STT
Sbjct: 1006 ETTSASTT 1013



>XP_005274885
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           E+TS STT
Sbjct: 867 ETTSASTT 874




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ESTSMSTT 8
            E+TS STT
Sbjct: 1006 ETTSASTT 1013



>XP_006723662
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESTSMSTTL 9
           EST+  TTL
Sbjct: 892 ESTNSDTTL 900



>XP_005260825
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESTSMSTTL 9
           EST+  TTL
Sbjct: 845 ESTNSDTTL 853



>XP_006723661
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESTSMSTTL 9
           EST+  TTL
Sbjct: 892 ESTNSDTTL 900



>XP_006719284
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           EST+ STT
Sbjct: 440 ESTNKSTT 447



>XP_006719283
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           EST+ STT
Sbjct: 732 ESTNKSTT 739



>XP_006719282
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           EST+ STT
Sbjct: 732 ESTNKSTT 739



>XP_005248836
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESTSMSTT 8
           E+TS STT
Sbjct: 867 ETTSASTT 874




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ESTSMSTT 8
            E+TS STT
Sbjct: 1006 ETTSASTT 1013



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.279   0.0876    0.183 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 229,082
Number of extensions: 503
Number of successful extensions: 35
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 35
Number of HSP's successfully gapped: 35
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)