Blast-Search of mutated query peptide against human proteome |
BLASTP 2.2.15 [Oct-15-2006] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= User_input (9 letters) Database: HUMAN_PROTEOME_FASTA 71,491 sequences; 45,948,801 total letters Searching..................................................doneScore E Sequences producing significant alignments: (bits) Value NP_443179 20 299 NP_001162588 17 3301 NP_001162589 17 3301 NP_065911 17 3301 NP_001424 17 3301 NP_001231681 17 3301 XP_006721832 17 3301 XP_005255101 17 3301 XP_006716835 17 3301 XP_006716834 17 3301 XP_006716833 17 3301 XP_006716832 17 3301 XP_006716812 17 3301 NP_671728 17 3301 NP_150296 17 3301 NP_005742 17 4312 NP_671714 17 4312 XP_006715890 17 4312 XP_005250160 17 4312 XP_005250159 17 4312 NP_055946 16 5631 NP_001180466 16 5631 NP_001243475 16 5631 NP_001139588 16 5631 NP_055966 16 5631 NP_001164209 16 5631 XP_006724043 16 5631 NP_258443 16 5631 NP_001139586 16 5631 NP_001180467 16 5631 NP_001243476 16 5631 NP_060950 16 5631 NP_001269553 16 7355 NP_001269555 16 7355 NP_001269554 16 7355 NP_005563 16 7355 NP_733821 16 7355 NP_001244303 16 7355 NP_733822 16 7355 NP_055524 16 7355 XP_006721637 16 7355 XP_005256849 16 7355 NP_055334 16 7355 NP_000072 15 9605 NP_001231913 15 9605 NP_005056 15 9605 NP_004975 15 9605 NP_004513 15 9605 NP_004512 15 9605 NP_055415 15 9605 NP_055392 15 9605 NP_001257655 15 9605 NP_001257656 15 9605 NP_060149 15 9605 NP_001092902 15 9605 NP_056182 15 9605 NP_001104595 15 9605 XP_006724643 15 9605 XP_006724642 15 9605 XP_006724278 15 9605 XP_006724277 15 9605 XP_006724276 15 9605 XP_006724275 15 9605 XP_005261529 15 9605 XP_006724274 15 9605 XP_006724273 15 9605 XP_005261528 15 9605 XP_005261527 15 9605 XP_006724138 15 9605 XP_005257534 15 9605 XP_005257533 15 9605 XP_005257532 15 9605 XP_005257531 15 9605 XP_005257530 15 9605 XP_005257529 15 9605 XP_005268046 15 9605 XP_006714747 15 9605 XP_006714745 15 9605 XP_005273087 15 9605 XP_006711794 15 9605 XP_005273086 15 9605 XP_005273085 15 9605 XP_005273084 15 9605>NP_443179 Length = 2170 Score = 20.4 bits (41), Expect = 299 Identities = 8/9 (88%), Positives = 8/9 (88%) Query: 1 ESTIEGTLH 9 EST EGTLH Sbjct: 555 ESTTEGTLH 563>NP_001162588 Length = 599 Score = 16.9 bits (32), Expect = 3301 Identities = 6/8 (75%), Positives = 7/8 (87%) Query: 2 STIEGTLH 9 ST+ GTLH Sbjct: 392 STVFGTLH 399>NP_001162589 Length = 754 Score = 16.9 bits (32), Expect = 3301 Identities = 6/8 (75%), Positives = 7/8 (87%) Query: 2 STIEGTLH 9 ST+ GTLH Sbjct: 400 STVFGTLH 407>NP_065911 Length = 746 Score = 16.9 bits (32), Expect = 3301 Identities = 6/8 (75%), Positives = 7/8 (87%) Query: 2 STIEGTLH 9 ST+ GTLH Sbjct: 392 STVFGTLH 399>NP_001424 Length = 977 Score = 16.9 bits (32), Expect = 3301 Identities = 5/8 (62%), Positives = 8/8 (100%) Query: 2 STIEGTLH 9 ST++G+LH Sbjct: 36 STLDGSLH 43>NP_001231681 Length = 1010 Score = 16.9 bits (32), Expect = 3301 Identities = 6/9 (66%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ES +EGT H Sbjct: 647 ESPLEGTSH 655>XP_006721832 Length = 1092 Score = 16.9 bits (32), Expect = 3301 Identities = 5/8 (62%), Positives = 8/8 (100%) Query: 2 STIEGTLH 9 ST++G+LH Sbjct: 151 STLDGSLH 158>XP_005255101 Length = 922 Score = 16.9 bits (32), Expect = 3301 Identities = 5/8 (62%), Positives = 8/8 (100%) Query: 2 STIEGTLH 9 ST++G+LH Sbjct: 92 STLDGSLH 99>XP_006716835 Length = 1048 Score = 16.9 bits (32), Expect = 3301 Identities = 6/9 (66%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ES +EGT H Sbjct: 620 ESPLEGTSH 628>XP_006716834 Length = 1076 Score = 16.9 bits (32), Expect = 3301 Identities = 6/9 (66%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ES +EGT H Sbjct: 648 ESPLEGTSH 656>XP_006716833 Length = 1083 Score = 16.9 bits (32), Expect = 3301 Identities = 6/9 (66%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ES +EGT H Sbjct: 666 ESPLEGTSH 674>XP_006716832 Length = 1093 Score = 16.9 bits (32), Expect = 3301 Identities = 6/9 (66%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ES +EGT H Sbjct: 666 ESPLEGTSH 674>XP_006716812 Length = 1074 Score = 16.9 bits (32), Expect = 3301 Identities = 6/9 (66%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ES +EGT H Sbjct: 657 ESPLEGTSH 665>NP_671728 Length = 992 Score = 16.9 bits (32), Expect = 3301 Identities = 6/9 (66%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ES +EGT H Sbjct: 639 ESPLEGTSH 647>NP_150296 Length = 974 Score = 16.9 bits (32), Expect = 3301 Identities = 5/8 (62%), Positives = 8/8 (100%) Query: 2 STIEGTLH 9 ST++G+LH Sbjct: 92 STLDGSLH 99>NP_005742 Length = 3907 Score = 16.5 bits (31), Expect = 4312 Identities = 7/9 (77%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ESTI TLH Sbjct: 80 ESTIMRTLH 88>NP_671714 Length = 3899 Score = 16.5 bits (31), Expect = 4312 Identities = 7/9 (77%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ESTI TLH Sbjct: 80 ESTIMRTLH 88>XP_006715890 Length = 3860 Score = 16.5 bits (31), Expect = 4312 Identities = 7/9 (77%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ESTI TLH Sbjct: 80 ESTIMRTLH 88>XP_005250160 Length = 3939 Score = 16.5 bits (31), Expect = 4312 Identities = 7/9 (77%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ESTI TLH Sbjct: 80 ESTIMRTLH 88>XP_005250159 Length = 3952 Score = 16.5 bits (31), Expect = 4312 Identities = 7/9 (77%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 ESTI TLH Sbjct: 80 ESTIMRTLH 88>NP_055946 Length = 677 Score = 16.2 bits (30), Expect = 5631 Identities = 5/8 (62%), Positives = 7/8 (87%) Query: 2 STIEGTLH 9 ST++G LH Sbjct: 110 STVKGELH 117>NP_001180466 Length = 210 Score = 16.2 bits (30), Expect = 5631 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 E T+E T+H Sbjct: 200 EETLEKTIH 208>NP_001243475 Length = 200 Score = 16.2 bits (30), Expect = 5631 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 E T+E T+H Sbjct: 190 EETLEKTIH 198>NP_001139588 Length = 1567 Score = 16.2 bits (30), Expect = 5631 Identities = 5/6 (83%), Positives = 6/6 (100%) Query: 4 IEGTLH 9 +EGTLH Sbjct: 914 LEGTLH 919>NP_055966 Length = 1571 Score = 16.2 bits (30), Expect = 5631 Identities = 5/6 (83%), Positives = 6/6 (100%) Query: 4 IEGTLH 9 +EGTLH Sbjct: 918 LEGTLH 923>NP_001164209 Length = 1182 Score = 16.2 bits (30), Expect = 5631 Identities = 5/9 (55%), Positives = 8/9 (88%) Query: 1 ESTIEGTLH 9 EST+E ++H Sbjct: 1034 ESTVEVSIH 1042>XP_006724043 Length = 1174 Score = 16.2 bits (30), Expect = 5631 Identities = 5/6 (83%), Positives = 6/6 (100%) Query: 4 IEGTLH 9 +EGTLH Sbjct: 918 LEGTLH 923>NP_258443 Length = 1035 Score = 16.2 bits (30), Expect = 5631 Identities = 6/7 (85%), Positives = 7/7 (100%) Query: 2 STIEGTL 8 STI+GTL Sbjct: 567 STIQGTL 573>NP_001139586 Length = 1110 Score = 16.2 bits (30), Expect = 5631 Identities = 5/6 (83%), Positives = 6/6 (100%) Query: 4 IEGTLH 9 +EGTLH Sbjct: 854 LEGTLH 859>NP_001180467 Length = 200 Score = 16.2 bits (30), Expect = 5631 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 E T+E T+H Sbjct: 190 EETLEKTIH 198>NP_001243476 Length = 184 Score = 16.2 bits (30), Expect = 5631 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 E T+E T+H Sbjct: 174 EETLEKTIH 182>NP_060950 Length = 230 Score = 16.2 bits (30), Expect = 5631 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 E T+E T+H Sbjct: 220 EETLEKTIH 228>NP_001269553 Length = 491 Score = 15.8 bits (29), Expect = 7355 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 76 TLEGELH 82>NP_001269555 Length = 614 Score = 15.8 bits (29), Expect = 7355 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 157 TLEGELH 163>NP_001269554 Length = 572 Score = 15.8 bits (29), Expect = 7355 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 157 TLEGELH 163>NP_005563 Length = 572 Score = 15.8 bits (29), Expect = 7355 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 157 TLEGELH 163>NP_733821 Length = 664 Score = 15.8 bits (29), Expect = 7355 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 157 TLEGELH 163>NP_001244303 Length = 574 Score = 15.8 bits (29), Expect = 7355 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 45 TLEGELH 51>NP_733822 Length = 634 Score = 15.8 bits (29), Expect = 7355 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 157 TLEGELH 163>NP_055524 Length = 3546 Score = 15.8 bits (29), Expect = 7355 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 TIE T+H Sbjct: 3526 TIESTIH 3532>XP_006721637 Length = 416 Score = 15.8 bits (29), Expect = 7355 Identities = 6/8 (75%), Positives = 7/8 (87%) Query: 1 ESTIEGTL 8 E+T EGTL Sbjct: 229 EATSEGTL 236>XP_005256849 Length = 435 Score = 15.8 bits (29), Expect = 7355 Identities = 6/8 (75%), Positives = 7/8 (87%) Query: 1 ESTIEGTL 8 E+T EGTL Sbjct: 248 EATSEGTL 255>NP_055334 Length = 444 Score = 15.8 bits (29), Expect = 7355 Identities = 6/8 (75%), Positives = 7/8 (87%) Query: 1 ESTIEGTL 8 E+T EGTL Sbjct: 257 EATSEGTL 264>NP_000072 Length = 3801 Score = 15.4 bits (28), Expect = 9605 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 TI+G LH Sbjct: 1800 TIQGILH 1806>NP_001231913 Length = 301 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 + IEGT H Sbjct: 116 TAIEGTAH 123>NP_005056 Length = 794 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 + IEGT H Sbjct: 116 TAIEGTAH 123>NP_004975 Length = 1032 Score = 15.4 bits (28), Expect = 9605 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 95 TMEGKLH 101>NP_004513 Length = 957 Score = 15.4 bits (28), Expect = 9605 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 95 TMEGKLH 101>NP_004512 Length = 963 Score = 15.4 bits (28), Expect = 9605 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 T+EG LH Sbjct: 94 TMEGKLH 100>NP_055415 Length = 535 Score = 15.4 bits (28), Expect = 9605 Identities = 5/5 (100%), Positives = 5/5 (100%) Query: 5 EGTLH 9 EGTLH Sbjct: 415 EGTLH 419>NP_055392 Length = 1058 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 41 EIEIEGRLH 49>NP_001257655 Length = 509 Score = 15.4 bits (28), Expect = 9605 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 E T+E T+H Sbjct: 162 ECTLETTVH 170>NP_001257656 Length = 461 Score = 15.4 bits (28), Expect = 9605 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 E T+E T+H Sbjct: 162 ECTLETTVH 170>NP_060149 Length = 913 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 ST+ GT H Sbjct: 423 STLRGTSH 430>NP_001092902 Length = 928 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 ST+ GT H Sbjct: 423 STLRGTSH 430>NP_056182 Length = 485 Score = 15.4 bits (28), Expect = 9605 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 E T+E T+H Sbjct: 138 ECTLETTVH 146>NP_001104595 Length = 1488 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 8/8 (100%) Query: 1 ESTIEGTL 8 +STIEG++ Sbjct: 1163 DSTIEGSV 1170>XP_006724643 Length = 1283 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 8/8 (100%) Query: 1 ESTIEGTL 8 +STIEG++ Sbjct: 958 DSTIEGSV 965>XP_006724642 Length = 1520 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 8/8 (100%) Query: 1 ESTIEGTL 8 +STIEG++ Sbjct: 1195 DSTIEGSV 1202>XP_006724278 Length = 978 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 78 EIEIEGRLH 86>XP_006724277 Length = 995 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 78 EIEIEGRLH 86>XP_006724276 Length = 1058 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 41 EIEIEGRLH 49>XP_006724275 Length = 1060 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 78 EIEIEGRLH 86>XP_005261529 Length = 1095 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 78 EIEIEGRLH 86>XP_006724274 Length = 1189 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 41 EIEIEGRLH 49>XP_006724273 Length = 1189 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 41 EIEIEGRLH 49>XP_005261528 Length = 1189 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 41 EIEIEGRLH 49>XP_005261527 Length = 1226 Score = 15.4 bits (28), Expect = 9605 Identities = 6/9 (66%), Positives = 6/9 (66%) Query: 1 ESTIEGTLH 9 E IEG LH Sbjct: 78 EIEIEGRLH 86>XP_006724138 Length = 437 Score = 15.4 bits (28), Expect = 9605 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 E T+E T+H Sbjct: 138 ECTLETTVH 146>XP_005257534 Length = 831 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 ST+ GT H Sbjct: 423 STLRGTSH 430>XP_005257533 Length = 835 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 ST+ GT H Sbjct: 423 STLRGTSH 430>XP_005257532 Length = 928 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 ST+ GT H Sbjct: 423 STLRGTSH 430>XP_005257531 Length = 935 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 ST+ GT H Sbjct: 423 STLRGTSH 430>XP_005257530 Length = 943 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 ST+ GT H Sbjct: 423 STLRGTSH 430>XP_005257529 Length = 950 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 ST+ GT H Sbjct: 423 STLRGTSH 430>XP_005268046 Length = 771 Score = 15.4 bits (28), Expect = 9605 Identities = 5/8 (62%), Positives = 6/8 (75%) Query: 2 STIEGTLH 9 + IEGT H Sbjct: 116 TAIEGTAH 123>XP_006714747 Length = 365 Score = 15.4 bits (28), Expect = 9605 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 EST + +LH Sbjct: 355 ESTTDNSLH 363>XP_006714745 Length = 396 Score = 15.4 bits (28), Expect = 9605 Identities = 5/9 (55%), Positives = 7/9 (77%) Query: 1 ESTIEGTLH 9 EST + +LH Sbjct: 386 ESTTDNSLH 394>XP_005273087 Length = 2788 Score = 15.4 bits (28), Expect = 9605 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 TI+G LH Sbjct: 1800 TIQGILH 1806>XP_006711794 Length = 3022 Score = 15.4 bits (28), Expect = 9605 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 TI+G LH Sbjct: 1021 TIQGILH 1027>XP_005273086 Length = 3264 Score = 15.4 bits (28), Expect = 9605 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 TI+G LH Sbjct: 1800 TIQGILH 1806>XP_005273085 Length = 3755 Score = 15.4 bits (28), Expect = 9605 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 TI+G LH Sbjct: 1800 TIQGILH 1806>XP_005273084 Length = 3801 Score = 15.4 bits (28), Expect = 9605 Identities = 5/7 (71%), Positives = 6/7 (85%) Query: 3 TIEGTLH 9 TI+G LH Sbjct: 1800 TIQGILH 1806Database: HUMAN_PROTEOME_FASTA Posted date: May 26, 2014 10:46 AM Number of letters in database: 45,948,801 Number of sequences in database: 71,491 Lambda K H 0.301 0.122 0.324 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 71491 Number of Hits to DB: 571,777 Number of extensions: 1024 Number of successful extensions: 83 Number of sequences better than 10000.0: 83 Number of HSP's gapped: 83 Number of HSP's successfully gapped: 83 Length of query: 9 Length of database: 45,948,801 Length adjustment: 0 Effective length of query: 9 Effective length of database: 45,948,801 Effective search space: 413539209 Effective search space used: 413539209 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 28 (15.2 bits) S2: 28 (15.4 bits)
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CANCERTOPE | Raghava's Group | IMTECH | CSIR | CRDD | GPSR Package |