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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              19     869
NP_653080                                                              19     869
XP_005267292                                                           19     869
XP_005267291                                                           19     869
XP_005267290                                                           19     869
NP_775897                                                              16    5631
NP_001159821                                                           16    5631
NP_001159820                                                           16    5631
NP_001159819                                                           16    5631
NP_005883                                                              16    5631
XP_006722133                                                           16    5631
XP_006722132                                                           16    5631
XP_006722131                                                           16    5631
XP_006722130                                                           16    5631
XP_006722129                                                           16    5631
XP_006722128                                                           16    5631
XP_006722127                                                           16    5631
XP_006722126                                                           16    5631
XP_006722125                                                           16    5631
XP_006721897                                                           16    5631
XP_006721896                                                           16    5631
NP_055565                                                              16    7355
NP_001139487                                                           16    7355
NP_036596                                                              15    9605
NP_115784                                                              15    9605
XP_006723226                                                           15    9605
XP_005263249                                                           15    9605
XP_006714356                                                           15    9605

>NP_005091
          Length = 1782

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ESTAVGQA 8
            ESTAVGQA
Sbjct: 1619 ESTAVGQA 1626



>NP_653080
          Length = 1684

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ESTAVGQA 8
            ESTAVGQA
Sbjct: 1521 ESTAVGQA 1528



>XP_005267292
          Length = 1677

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ESTAVGQA 8
            ESTAVGQA
Sbjct: 1514 ESTAVGQA 1521



>XP_005267291
          Length = 1684

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ESTAVGQA 8
            ESTAVGQA
Sbjct: 1521 ESTAVGQA 1528



>XP_005267290
          Length = 1782

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ESTAVGQA 8
            ESTAVGQA
Sbjct: 1619 ESTAVGQA 1626



>NP_775897
          Length = 606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TAVGQAR 9
          TA+GQAR
Sbjct: 6  TALGQAR 12



>NP_001159821
          Length = 606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TAVGQAR 9
          TA+GQAR
Sbjct: 6  TALGQAR 12



>NP_001159820
          Length = 606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TAVGQAR 9
          TA+GQAR
Sbjct: 6  TALGQAR 12



>NP_001159819
          Length = 606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TAVGQAR 9
          TA+GQAR
Sbjct: 6  TALGQAR 12



>NP_005883
          Length = 1100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 449 ESTAMGASR 457



>XP_006722133
          Length = 1104

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 449 ESTAMGPSR 457



>XP_006722132
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 455 ESTAMGPSR 463



>XP_006722131
          Length = 1100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 449 ESTAMGPSR 457



>XP_006722130
          Length = 1106

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 455 ESTAMGPSR 463



>XP_006722129
          Length = 1110

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 455 ESTAMGPSR 463



>XP_006722128
          Length = 1148

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 439 ESTAMGPSR 447



>XP_006722127
          Length = 1154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 445 ESTAMGPSR 453



>XP_006722126
          Length = 1158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 449 ESTAMGPSR 457



>XP_006722125
          Length = 1164

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESTAVGQAR 9
           ESTA+G +R
Sbjct: 455 ESTAMGPSR 463



>XP_006721897
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TAVGQAR 9
          TA+GQAR
Sbjct: 6  TALGQAR 12



>XP_006721896
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TAVGQAR 9
          TA+GQAR
Sbjct: 6  TALGQAR 12



>NP_055565
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TAVGQAR 9
           TAVGQ R
Sbjct: 469 TAVGQTR 475



>NP_001139487
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TAVGQAR 9
           TAVGQ R
Sbjct: 469 TAVGQTR 475



>NP_036596
          Length = 1013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESTAVGQAR 9
           +STAVG  R
Sbjct: 956 DSTAVGLGR 964



>NP_115784
          Length = 1483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ESTAVGQAR 9
            E  AVGQ+R
Sbjct: 1469 EPEAVGQSR 1477



>XP_006723226
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AVGQAR 9
           AVGQAR
Sbjct: 316 AVGQAR 321



>XP_005263249
          Length = 727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESTAVGQAR 9
           +STAVG  R
Sbjct: 670 DSTAVGLGR 678



>XP_006714356
          Length = 964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESTAVGQAR 9
           +STAVG  R
Sbjct: 907 DSTAVGLGR 915



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.109    0.260 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 354,113
Number of extensions: 320
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)