Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              17    2528
XP_005271621                                                           17    2528
XP_006718907                                                           17    2528
XP_006718906                                                           17    2528
XP_005271619                                                           17    2528
XP_005271618                                                           17    2528
NP_055973                                                              15    9605
NP_001243805                                                           15    9605
NP_694856                                                              15    9605
NP_001243806                                                           15    9605
XP_006716810                                                           15    9605
XP_005251476                                                           15    9605
XP_005251475                                                           15    9605
XP_005251473                                                           15    9605
XP_005251474                                                           15    9605
XP_005251472                                                           15    9605
XP_005251471                                                           15    9605
XP_005251470                                                           15    9605
XP_006716809                                                           15    9605
XP_006716808                                                           15    9605
XP_006716807                                                           15    9605
XP_006716806                                                           15    9605
XP_005251468                                                           15    9605
XP_005251467                                                           15    9605
>NP_000042
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESSQKSALL 9
           ESSQKS LL
Sbjct: 473 ESSQKSDLL 481
>XP_005271621
          Length = 2708

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESSQKSALL 9
           ESSQKS LL
Sbjct: 125 ESSQKSDLL 133
>XP_006718907
          Length = 3050

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESSQKSALL 9
           ESSQKS LL
Sbjct: 473 ESSQKSDLL 481
>XP_006718906
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESSQKSALL 9
           ESSQKS LL
Sbjct: 473 ESSQKSDLL 481
>XP_005271619
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESSQKSALL 9
           ESSQKS LL
Sbjct: 473 ESSQKSDLL 481
>XP_005271618
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESSQKSALL 9
           ESSQKS LL
Sbjct: 473 ESSQKSDLL 481
>NP_055973
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132
>NP_001243805
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132
>NP_694856
          Length = 1194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSQKSAL 8
           SSQKSA+
Sbjct: 968 SSQKSAI 974
>NP_001243806
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132
>XP_006716810
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSQKSAL 8
           SSQKSA+
Sbjct: 968 SSQKSAI 974
>XP_005251476
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSQKSAL 8
           SSQKSA+
Sbjct: 968 SSQKSAI 974
>XP_005251475
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSQKSAL 8
           SSQKSA+
Sbjct: 968 SSQKSAI 974
>XP_005251473
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSQKSAL 8
           SSQKSA+
Sbjct: 968 SSQKSAI 974
>XP_005251474
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSQKSAL 8
           SSQKSA+
Sbjct: 968 SSQKSAI 974
>XP_005251472
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSQKSAL 8
           SSQKSA+
Sbjct: 968 SSQKSAI 974
>XP_005251471
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSQKSAL 8
           SSQKSA+
Sbjct: 968 SSQKSAI 974
>XP_005251470
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1046 SSQKSAI 1052
>XP_006716809
          Length = 1334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1108 SSQKSAI 1114
>XP_006716808
          Length = 1346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1108 SSQKSAI 1114
>XP_006716807
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132
>XP_006716806
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132
>XP_005251468
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132
>XP_005251467
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSQKSAL 8
            SSQKSA+
Sbjct: 1126 SSQKSAI 1132
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.283   0.0990    0.202 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 228,108
Number of extensions: 198
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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