Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              19     665
NP_444254                                                              19     665
NP_444253                                                              19     665
NP_444255                                                              19     665
XP_005247551                                                           19     665
XP_005247550                                                           19     665
XP_006713712                                                           19     665
XP_005247549                                                           19     665
NP_002197                                                              17    4312
NP_001138468                                                           17    4312
NP_001138469                                                           17    4312
NP_057412                                                              17    4312
NP_001018098                                                           17    4312
NP_060154                                                              17    4312
NP_060550                                                              17    4312
NP_065872                                                              17    4312
NP_653234                                                              17    4312
XP_005268907                                                           17    4312
XP_005268906                                                           17    4312
XP_005268905                                                           17    4312
XP_005268904                                                           17    4312
XP_005268903                                                           17    4312
XP_005268902                                                           17    4312
XP_005268901                                                           17    4312
XP_005268899                                                           17    4312
XP_005268898                                                           17    4312
XP_005268897                                                           17    4312
XP_005268896                                                           17    4312
XP_006716247                                                           17    4312
XP_005250778                                                           17    4312
XP_006713027                                                           17    4312
XP_006713026                                                           17    4312
XP_006713025                                                           17    4312
XP_006713024                                                           17    4312
NP_940953                                                              16    5631
XP_006711367                                                           16    5631
XP_005273178                                                           16    5631
XP_005244984                                                           16    5631
NP_001257545                                                           16    7355
NP_002754                                                              16    7355
XP_006711518                                                           16    7355
XP_005273252                                                           16    7355
XP_005273253                                                           16    7355
XP_005273251                                                           16    7355
NP_828848                                                              16    7355
NP_954635                                                              15    9605
NP_000679                                                              15    9605
NP_001231800                                                           15    9605
NP_001334                                                              15    9605
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_001243779                                                           15    9605
NP_596869                                                              15    9605
NP_059509                                                              15    9605
XP_005259084                                                           15    9605
XP_006723316                                                           15    9605
XP_005259653                                                           15    9605
XP_005265002                                                           15    9605
XP_005265001                                                           15    9605
XP_005246888                                                           15    9605
XP_006712788                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
NP_060324                                                              15    9605
NP_064555                                                              15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605
>NP_444256
          Length = 1794

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESQGTASAF 9
            ESQGTA AF
Sbjct: 1023 ESQGTAPAF 1031
>NP_444254
          Length = 1845

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESQGTASAF 9
            ESQGTA AF
Sbjct: 1023 ESQGTAPAF 1031
>NP_444253
          Length = 1914

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESQGTASAF 9
            ESQGTA AF
Sbjct: 1092 ESQGTAPAF 1100
>NP_444255
          Length = 1863

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESQGTASAF 9
            ESQGTA AF
Sbjct: 1092 ESQGTAPAF 1100
>XP_005247551
          Length = 1855

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESQGTASAF 9
            ESQGTA AF
Sbjct: 1033 ESQGTAPAF 1041
>XP_005247550
          Length = 1856

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESQGTASAF 9
            ESQGTA AF
Sbjct: 1102 ESQGTAPAF 1110
>XP_006713712
          Length = 1923

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESQGTASAF 9
            ESQGTA AF
Sbjct: 1102 ESQGTAPAF 1110
>XP_005247549
          Length = 1924

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESQGTASAF 9
            ESQGTA AF
Sbjct: 1102 ESQGTAPAF 1110
>NP_002197
          Length = 1137

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QGTASAF 9
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>NP_001138468
          Length = 1141

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QGTASAF 9
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>NP_001138469
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QGTASAF 9
           QGTA+AF
Sbjct: 102 QGTAAAF 108
>NP_057412
          Length = 959

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ESQGTASA 8
           +SQGTAS+
Sbjct: 653 DSQGTASS 660
>NP_001018098
          Length = 3628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SQGTASAF 9
            S+GTAS F
Sbjct: 2407 SEGTASTF 2414
>NP_060154
          Length = 3710

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SQGTASAF 9
            S+GTAS F
Sbjct: 2364 SEGTASTF 2371
>NP_060550
          Length = 3585

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SQGTASAF 9
            S+GTAS F
Sbjct: 2364 SEGTASTF 2371
>NP_065872
          Length = 3753

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SQGTASAF 9
            S+GTAS F
Sbjct: 2407 SEGTASTF 2414
>NP_653234
          Length = 1107

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SQGTASAF 9
            SQGT S+F
Sbjct: 1056 SQGTVSSF 1063
>XP_005268907
          Length = 979

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  QGTASAF 9
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268906
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  QGTASAF 9
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268905
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  QGTASAF 9
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268904
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  QGTASAF 9
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268903
          Length = 1024

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  QGTASAF 9
          QGTA+AF
Sbjct: 86 QGTAAAF 92
>XP_005268902
          Length = 1024

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  QGTASAF 9
          QGTA+AF
Sbjct: 86 QGTAAAF 92
>XP_005268901
          Length = 1068

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  QGTASAF 9
          QGTA+AF
Sbjct: 86 QGTAAAF 92
>XP_005268899
          Length = 1131

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QGTASAF 9
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005268898
          Length = 1162

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QGTASAF 9
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005268897
          Length = 1175

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QGTASAF 9
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005268896
          Length = 1181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QGTASAF 9
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_006716247
          Length = 638

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ESQGTASA 8
           +SQGTAS+
Sbjct: 332 DSQGTASS 339
>XP_005250778
          Length = 805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ESQGTASA 8
           +SQGTAS+
Sbjct: 653 DSQGTASS 660
>XP_006713027
          Length = 930

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SQGTASAF 9
           SQGT S+F
Sbjct: 879 SQGTVSSF 886
>XP_006713026
          Length = 986

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SQGTASAF 9
           SQGT S+F
Sbjct: 935 SQGTVSSF 942
>XP_006713025
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SQGTASAF 9
            SQGT S+F
Sbjct: 1038 SQGTVSSF 1045
>XP_006713024
          Length = 1108

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SQGTASAF 9
            SQGT S+F
Sbjct: 1057 SQGTVSSF 1064
>NP_940953
          Length = 1907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ESQGTASA 8
           ESQG+A+A
Sbjct: 890 ESQGSAAA 897
>XP_006711367
          Length = 1872

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ESQGTASA 8
           ESQG+A+A
Sbjct: 890 ESQGSAAA 897
>XP_005273178
          Length = 1931

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ESQGTASA 8
           ESQG+A+A
Sbjct: 890 ESQGSAAA 897
>XP_005244984
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ESQGTAS 7
           ES+GTAS
Sbjct: 441 ESEGTAS 447
>NP_001257545
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GTASAF 9
          GTASAF
Sbjct: 28 GTASAF 33
>NP_002754
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GTASAF 9
          GTASAF
Sbjct: 28 GTASAF 33
>XP_006711518
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GTASAF 9
          GTASAF
Sbjct: 28 GTASAF 33
>XP_005273252
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GTASAF 9
          GTASAF
Sbjct: 28 GTASAF 33
>XP_005273253
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GTASAF 9
          GTASAF
Sbjct: 28 GTASAF 33
>XP_005273251
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  GTASAF 9
          GTASAF
Sbjct: 28 GTASAF 33
>NP_828848
          Length = 818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GTASAF 9
           GTASAF
Sbjct: 202 GTASAF 207
>NP_954635
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SQGTAS 7
           SQGTAS
Sbjct: 101 SQGTAS 106
>NP_000679
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SQGTAS 7
           SQGTAS
Sbjct: 101 SQGTAS 106
>NP_001231800
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SQGTASAF 9
           S GT SAF
Sbjct: 654 SSGTLSAF 661
>NP_001334
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SQGTASAF 9
           S GT SAF
Sbjct: 675 SSGTLSAF 682
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 16521 SSGTKSAF 16528
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 16646 SSGTKSAF 16653
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 23945 SSGTKSAF 23952
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 23018 SSGTKSAF 23025
>NP_059509
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QGTASA 8
           QGTASA
Sbjct: 361 QGTASA 366
>XP_005259084
          Length = 99

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ESQGTASA 8
          E  GTASA
Sbjct: 80 EDDGTASA 87
>XP_006723316
          Length = 120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ESQGTASA 8
           E  GTASA
Sbjct: 101 EDDGTASA 108
>XP_005259653
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SQGTASA 8
           SQG+ASA
Sbjct: 165 SQGSASA 171
>XP_005265002
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SQGTAS 7
           SQGTAS
Sbjct: 101 SQGTAS 106
>XP_005265001
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SQGTAS 7
           SQGTAS
Sbjct: 118 SQGTAS 123
>XP_005246888
          Length = 22663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 12258 SSGTKSAF 12265
>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 13617 SSGTKSAF 13624
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 23573 SSGTKSAF 23580
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 25079 SSGTKSAF 25086
>NP_060324
          Length = 188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ESQGTASA 8
           E  GTASA
Sbjct: 169 EDDGTASA 176
>NP_064555
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SQGTASA 8
           SQG+ASA
Sbjct: 165 SQGSASA 171
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 25586 SSGTKSAF 25593
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     SQGTASAF 9
             S GT SAF
Sbjct: 16713 SSGTKSAF 16720
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.106    0.259 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 458,535
Number of extensions: 544
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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