Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1135
NP_001185763                                                           18    1135
NP_055459                                                              18    1135
XP_006726410                                                           18    1135
XP_006711719                                                           18    1135
XP_006711718                                                           18    1135
XP_006711717                                                           18    1135
XP_006711716                                                           18    1135
XP_006711715                                                           18    1135
XP_006711714                                                           18    1135
XP_006711713                                                           18    1135
XP_006711712                                                           18    1135
XP_006711711                                                           18    1135
XP_006711710                                                           18    1135
XP_006711709                                                           18    1135
XP_005277503                                                           18    1135
XP_005273038                                                           18    1135
XP_006711708                                                           18    1135
XP_005277500                                                           18    1135
XP_006711707                                                           18    1135
XP_005277499                                                           18    1135
XP_006711706                                                           18    1135
XP_006711705                                                           18    1135
XP_006711164                                                           18    1135
XP_006710143                                                           18    1135
XP_006710142                                                           18    1135
XP_006710141                                                           18    1135
NP_056078                                                              16    5631
NP_001167587                                                           16    5631
NP_001157879                                                           16    5631
XP_005254315                                                           16    5631
XP_005254314                                                           16    5631
XP_006720509                                                           16    5631
XP_005254313                                                           16    5631
XP_005254312                                                           16    5631
NP_001127880                                                           16    7355
NP_000824                                                              16    7355
NP_001127879                                                           16    7355
NP_775922                                                              16    7355
XP_005255325                                                           16    7355
XP_005255324                                                           16    7355
NP_079279                                                              15    9605
NP_001001912                                                           15    9605
NP_001138663                                                           15    9605
NP_001005463                                                           15    9605
NP_115518                                                              15    9605
NP_001124296                                                           15    9605
XP_006723400                                                           15    9605
XP_005259240                                                           15    9605
XP_006722395                                                           15    9605
XP_006722393                                                           15    9605
XP_006722392                                                           15    9605
XP_006722391                                                           15    9605
XP_006722390                                                           15    9605
XP_005258166                                                           15    9605
XP_006722389                                                           15    9605
XP_005258165                                                           15    9605
XP_005258164                                                           15    9605
XP_006717806                                                           15    9605
XP_005252726                                                           15    9605
XP_006717805                                                           15    9605
XP_006717804                                                           15    9605
XP_005252725                                                           15    9605
XP_005252724                                                           15    9605
XP_006717803                                                           15    9605
XP_006717802                                                           15    9605
NP_001124297                                                           15    9605
NP_003160                                                              15    9605
NP_001104490                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1626 ESNSNPISL 1634
>NP_001185763
          Length = 2362

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1670 ESNSNPISL 1678
>NP_055459
          Length = 2346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1670 ESNSNPISL 1678
>XP_006726410
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1473 ESNSNPISL 1481
>XP_006711719
          Length = 2302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1626 ESNSNPISL 1634
>XP_006711718
          Length = 1436

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           ESNSN ISL
Sbjct: 677 ESNSNPISL 685
>XP_006711717
          Length = 2385

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1626 ESNSNPISL 1634
>XP_006711716
          Length = 2411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1735 ESNSNPISL 1743
>XP_006711715
          Length = 2428

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1669 ESNSNPISL 1677
>XP_006711714
          Length = 2429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1670 ESNSNPISL 1678
>XP_006711713
          Length = 2432

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1673 ESNSNPISL 1681
>XP_006711712
          Length = 2473

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1833 ESNSNPISL 1841
>XP_006711711
          Length = 2482

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1723 ESNSNPISL 1731
>XP_006711710
          Length = 2494

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1735 ESNSNPISL 1743
>XP_006711709
          Length = 2495

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1736 ESNSNPISL 1744
>XP_005277503
          Length = 2498

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1833 ESNSNPISL 1841
>XP_005273038
          Length = 2509

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1833 ESNSNPISL 1841
>XP_006711708
          Length = 2512

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1833 ESNSNPISL 1841
>XP_005277500
          Length = 2525

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1833 ESNSNPISL 1841
>XP_006711707
          Length = 2553

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1833 ESNSNPISL 1841
>XP_005277499
          Length = 2561

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1833 ESNSNPISL 1841
>XP_006711706
          Length = 2591

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1832 ESNSNPISL 1840
>XP_006711705
          Length = 2592

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1833 ESNSNPISL 1841
>XP_006711164
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            ESNSN ISL
Sbjct: 1473 ESNSNPISL 1481
>XP_006710143
          Length = 562

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           ESNSN ISL
Sbjct: 512 ESNSNPISL 520
>XP_006710142
          Length = 671

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           ESNSN ISL
Sbjct: 621 ESNSNPISL 629
>XP_006710141
          Length = 672

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           ESNSN ISL
Sbjct: 622 ESNSNPISL 630
>NP_056078
          Length = 3036

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            E NS+T+S+
Sbjct: 1059 EDNSSTVSI 1067
>NP_001167587
          Length = 3037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            E NS+T+S+
Sbjct: 1059 EDNSSTVSI 1067
>NP_001157879
          Length = 264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SNSNTISL 9
           SNS+T+SL
Sbjct: 255 SNSSTLSL 262
>XP_005254315
          Length = 2576

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            E NS+T+S+
Sbjct: 1059 EDNSSTVSI 1067
>XP_005254314
          Length = 2605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            E NS+T+S+
Sbjct: 1059 EDNSSTVSI 1067
>XP_006720509
          Length = 2646

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            E NS+T+S+
Sbjct: 1059 EDNSSTVSI 1067
>XP_005254313
          Length = 3057

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            E NS+T+S+
Sbjct: 1059 EDNSSTVSI 1067
>XP_005254312
          Length = 3058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            E NS+T+S+
Sbjct: 1059 EDNSSTVSI 1067
>NP_001127880
          Length = 1281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESNSNTISL 9
           ESN NT+ +
Sbjct: 990 ESNPNTVEV 998
>NP_000824
          Length = 1464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESNSNTISL 9
           ESN NT+ +
Sbjct: 990 ESNPNTVEV 998
>NP_001127879
          Length = 1464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESNSNTISL 9
           ESN NT+ +
Sbjct: 990 ESNPNTVEV 998
>NP_775922
          Length = 6996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ESNSNTISL 9
            +SNS T+SL
Sbjct: 3997 DSNSLTVSL 4005
>XP_005255325
          Length = 1333

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ESNSNTISL 9
            ESN NT+ +
Sbjct: 1042 ESNPNTVEV 1050
>XP_005255324
          Length = 1516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ESNSNTISL 9
            ESN NT+ +
Sbjct: 1042 ESNPNTVEV 1050
>NP_079279
          Length = 1910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    NSNTISL 9
            NS+TISL
Sbjct: 1572 NSSTISL 1578
>NP_001001912
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SNSNTISL 9
           +NS TISL
Sbjct: 201 TNSGTISL 208
>NP_001138663
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NSNTISL 9
           N NT+SL
Sbjct: 196 NDNTVSL 202
>NP_001005463
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ESNSNTIS 8
           +SN NT+S
Sbjct: 471 QSNYNTVS 478
>NP_115518
          Length = 2537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 277 ENNSSLISL 285
>NP_001124296
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESNSNTISL 9
           E + NTISL
Sbjct: 297 EPSQNTISL 305
>XP_006723400
          Length = 1083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESNSNTISL 9
           E + NTISL
Sbjct: 293 EPSQNTISL 301
>XP_005259240
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESNSNTISL 9
           E + NTISL
Sbjct: 297 EPSQNTISL 305
>XP_006722395
          Length = 1419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 277 ENNSSLISL 285
>XP_006722393
          Length = 2199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 277 ENNSSLISL 285
>XP_006722392
          Length = 2444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 183 ENNSSLISL 191
>XP_006722391
          Length = 2448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 187 ENNSSLISL 195
>XP_006722390
          Length = 2467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 277 ENNSSLISL 285
>XP_005258166
          Length = 2468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 277 ENNSSLISL 285
>XP_006722389
          Length = 2506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 277 ENNSSLISL 285
>XP_005258165
          Length = 2534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 273 ENNSSLISL 281
>XP_005258164
          Length = 2538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESNSNTISL 9
           E+NS+ ISL
Sbjct: 277 ENNSSLISL 285
>XP_006717806
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ESNSNTIS 8
           +SN NT+S
Sbjct: 480 QSNYNTVS 487
>XP_005252726
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ESNSNTIS 8
           +SN NT+S
Sbjct: 471 QSNYNTVS 478
>XP_006717805
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ESNSNTIS 8
           +SN NT+S
Sbjct: 480 QSNYNTVS 487
>XP_006717804
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ESNSNTIS 8
           +SN NT+S
Sbjct: 480 QSNYNTVS 487
>XP_005252725
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ESNSNTIS 8
           +SN NT+S
Sbjct: 480 QSNYNTVS 487
>XP_005252724
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ESNSNTIS 8
           +SN NT+S
Sbjct: 471 QSNYNTVS 478
>XP_006717803
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ESNSNTIS 8
           +SN NT+S
Sbjct: 480 QSNYNTVS 487
>XP_006717802
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ESNSNTIS 8
           +SN NT+S
Sbjct: 480 QSNYNTVS 487
>NP_001124297
          Length = 1083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESNSNTISL 9
           E + NTISL
Sbjct: 293 EPSQNTISL 301
>NP_003160
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESNSNTISL 9
           E + NTISL
Sbjct: 297 EPSQNTISL 305
>NP_001104490
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ESNSNTISL 9
           E + NTISL
Sbjct: 297 EPSQNTISL 305
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280    0.100    0.221 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 410,020
Number of extensions: 574
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)

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