Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001158238                                                           18    1482
NP_008816                                                              18    1482
XP_005256014                                                           18    1482
NP_005119                                                              18    1935
XP_006724131                                                           18    1935
NP_000876                                                              17    2528
NP_002099                                                              16    5631
NP_038478                                                              16    5631
NP_001245263                                                           16    5631
NP_001276904                                                           16    5631
NP_006112                                                              16    5631
XP_005268878                                                           16    5631
XP_006712537                                                           16    5631
XP_006712536                                                           16    5631
XP_005246557                                                           16    5631
XP_006712535                                                           16    5631
XP_006712534                                                           16    5631
XP_006712533                                                           16    5631
XP_006712532                                                           16    5631
XP_006712531                                                           16    5631
XP_006712530                                                           16    5631
XP_006712529                                                           16    5631
XP_006712528                                                           16    5631
XP_006712527                                                           16    5631
XP_005246549                                                           16    5631
XP_006712526                                                           16    5631
XP_006712525                                                           16    5631
XP_005246546                                                           16    5631
XP_006712524                                                           16    5631
XP_005246545                                                           16    5631
NP_062541                                                              15    9605
NP_671494                                                              15    9605
NP_006268                                                              15    9605
NP_060009                                                              15    9605
XP_006721125                                                           15    9605
>NP_001158238
          Length = 2789

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  ESLVNLGES 9
          E L+NLGES
Sbjct: 11 EELMNLGES 19
>NP_008816
          Length = 3703

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ESLVNLGES 9
           E L+NLGES
Sbjct: 925 EELMNLGES 933
>XP_005256014
          Length = 3702

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ESLVNLGES 9
           E L+NLGES
Sbjct: 925 EELMNLGES 933
>NP_005119
          Length = 2298

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ESLVNLGE 8
            ESL+NLG+
Sbjct: 1421 ESLINLGQ 1428
>XP_006724131
          Length = 2298

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ESLVNLGE 8
            ESL+NLG+
Sbjct: 1421 ESLINLGQ 1428
>NP_000876
          Length = 1032

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ESLVNLGE 8
           ES+VNLG+
Sbjct: 370 ESIVNLGD 377
>NP_002099
          Length = 657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESLVNLGE 8
           E LVNLG+
Sbjct: 124 EDLVNLGK 131
>NP_038478
          Length = 2168

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1123 EGLLNIGDS 1131
>NP_001245263
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESLVNLGE 8
           E LVNLG+
Sbjct: 124 EDLVNLGK 131
>NP_001276904
          Length = 2132

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1087 EGLLNIGDS 1095
>NP_006112
          Length = 644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  SLVNLGES 9
          SLVNLG S
Sbjct: 66 SLVNLGGS 73
>XP_005268878
          Length = 556

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESLVNLGE 8
           E LVNLG+
Sbjct: 124 EDLVNLGK 131
>XP_006712537
          Length = 1952

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1134 EGLLNIGDS 1142
>XP_006712536
          Length = 2082

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1002 EGLLNIGDS 1010
>XP_005246557
          Length = 2095

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1015 EGLLNIGDS 1023
>XP_006712535
          Length = 2095

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1015 EGLLNIGDS 1023
>XP_006712534
          Length = 2114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1034 EGLLNIGDS 1042
>XP_006712533
          Length = 2116

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1036 EGLLNIGDS 1044
>XP_006712532
          Length = 2141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1096 EGLLNIGDS 1104
>XP_006712531
          Length = 2169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1089 EGLLNIGDS 1097
>XP_006712530
          Length = 2176

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1096 EGLLNIGDS 1104
>XP_006712529
          Length = 2179

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1134 EGLLNIGDS 1142
>XP_006712528
          Length = 2180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1100 EGLLNIGDS 1108
>XP_006712527
          Length = 2203

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1123 EGLLNIGDS 1131
>XP_005246549
          Length = 2212

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1132 EGLLNIGDS 1140
>XP_006712526
          Length = 2212

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1132 EGLLNIGDS 1140
>XP_006712525
          Length = 2212

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1132 EGLLNIGDS 1140
>XP_005246546
          Length = 2214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1134 EGLLNIGDS 1142
>XP_006712524
          Length = 2214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1134 EGLLNIGDS 1142
>XP_005246545
          Length = 2214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ESLVNLGES 9
            E L+N+G+S
Sbjct: 1134 EGLLNIGDS 1142
>NP_062541
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ESLVNLGES 9
           +SL++LG S
Sbjct: 209 QSLIDLGSS 217
>NP_671494
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ESLVNLGES 9
           +SL++LG S
Sbjct: 209 QSLIDLGSS 217
>NP_006268
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ESLVNLGES 9
           +SL++LG S
Sbjct: 209 QSLIDLGSS 217
>NP_060009
          Length = 4116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SLVNLGES 9
            SL+NLG +
Sbjct: 3893 SLINLGRA 3900
>XP_006721125
          Length = 4070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SLVNLGES 9
            SL+NLG +
Sbjct: 3847 SLINLGRA 3854
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.120    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 496,561
Number of extensions: 938
Number of successful extensions: 35
Number of sequences better than 10000.0: 35
Number of HSP's gapped: 35
Number of HSP's successfully gapped: 35
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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