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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_001138462                                                           17    4312
NP_000740                                                              16    5631
NP_056128                                                              16    5631
NP_001185594                                                           16    5631
XP_005271537                                                           16    5631
XP_005271535                                                           16    5631
XP_006718868                                                           16    5631
NP_001008740                                                           16    5631
NP_001257452                                                           15    9605
NP_001257453                                                           15    9605
NP_758840                                                              15    9605
NP_068374                                                              15    9605
NP_001257454                                                           15    9605
NP_001360                                                              15    9605
NP_001164228                                                           15    9605
NP_001160071                                                           15    9605
NP_001160072                                                           15    9605
NP_001164227                                                           15    9605
NP_660327                                                              15    9605
NP_000129                                                              15    9605
NP_060542                                                              15    9605
NP_849143                                                              15    9605
NP_004834                                                              15    9605
XP_006724796                                                           15    9605
XP_006724795                                                           15    9605
XP_006724794                                                           15    9605
XP_006724793                                                           15    9605
XP_005248319                                                           15    9605

>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ESLSLSTSG 9
            ESLSLST+G
Sbjct: 1464 ESLSLSTAG 1472



>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ESLSLSTSG 9
            ESLSLST+G
Sbjct: 1259 ESLSLSTAG 1267



>NP_001138462
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LSLSTSG 9
            LSLSTSG
Sbjct: 1290 LSLSTSG 1296



>NP_000740
          Length = 458

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ESLSLSTS 8
           E LSLSTS
Sbjct: 263 EKLSLSTS 270



>NP_056128
          Length = 1544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESLSLSTSG 9
            +S SLSTSG
Sbjct: 1193 QSHSLSTSG 1201



>NP_001185594
          Length = 1525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESLSLSTSG 9
            +S SLSTSG
Sbjct: 1174 QSHSLSTSG 1182



>XP_005271537
          Length = 1441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESLSLSTSG 9
            +S SLSTSG
Sbjct: 1090 QSHSLSTSG 1098



>XP_005271535
          Length = 1504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESLSLSTSG 9
            +S SLSTSG
Sbjct: 1153 QSHSLSTSG 1161



>XP_006718868
          Length = 1519

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ESLSLSTSG 9
            +S SLSTSG
Sbjct: 1168 QSHSLSTSG 1176



>NP_001008740
          Length = 182

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  ESLSLST 7
          ESLSLST
Sbjct: 14 ESLSLST 20



>NP_001257452
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LSLSTSG 9
          LSL+TSG
Sbjct: 15 LSLTTSG 21



>NP_001257453
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LSLSTSG 9
          LSL+TSG
Sbjct: 15 LSLTTSG 21



>NP_758840
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LSLSTSG 9
          LSL+TSG
Sbjct: 15 LSLTTSG 21



>NP_068374
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LSLSTSG 9
          LSL+TSG
Sbjct: 15 LSLTTSG 21



>NP_001257454
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LSLSTSG 9
          LSL+TSG
Sbjct: 15 LSLTTSG 21



>NP_001360
          Length = 4624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ESLSLSTSG 9
            ESL L T+G
Sbjct: 3352 ESLKLMTAG 3360



>NP_001164228
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ESLSLSTS 8
          ESLSLS S
Sbjct: 54 ESLSLSDS 61



>NP_001160071
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ESLSLSTS 8
          ESLSLS S
Sbjct: 88 ESLSLSDS 95



>NP_001160072
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ESLSLSTS 8
           ESLSLS S
Sbjct: 107 ESLSLSDS 114



>NP_001164227
          Length = 266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ESLSLSTS 8
           ESLSLS S
Sbjct: 107 ESLSLSDS 114



>NP_660327
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ESLSLSTS 8
          ESLSLS S
Sbjct: 88 ESLSLSDS 95



>NP_000129
          Length = 2871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ESLSLSTSG 9
            E  SLS+SG
Sbjct: 2042 EGFSLSSSG 2050



>NP_060542
          Length = 2144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSLSTSG 9
           +SLSTSG
Sbjct: 464 VSLSTSG 470



>NP_849143
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSLSTSG 9
           SLS +TSG
Sbjct: 224 SLSFNTSG 231



>NP_004834
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSLSTSG 9
           LSL+TSG
Sbjct: 534 LSLATSG 540



>XP_006724796
          Length = 223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ESLSLSTS 8
          ESLSLS S
Sbjct: 88 ESLSLSDS 95



>XP_006724795
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ESLSLSTS 8
           ESLSLS S
Sbjct: 107 ESLSLSDS 114



>XP_006724794
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ESLSLSTS 8
          ESLSLS S
Sbjct: 92 ESLSLSDS 99



>XP_006724793
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ESLSLSTS 8
           ESLSLS S
Sbjct: 107 ESLSLSDS 114



>XP_005248319
          Length = 4609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ESLSLSTSG 9
            ESL L T+G
Sbjct: 3337 ESLKLMTAG 3345



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280    0.102    0.223 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 313,635
Number of extensions: 510
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)