Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           19     665
NP_001277143                                                           19     665
NP_001077383                                                           19     665
NP_001320                                                              19     665
NP_073713                                                              19     665
XP_005269629                                                           19     665
XP_005269628                                                           19     665
XP_005269627                                                           19     665
XP_005269626                                                           19     665
XP_006717706                                                           19     665
XP_005269625                                                           19     665
XP_005269624                                                           19     665
XP_006717705                                                           19     665
XP_005269622                                                           19     665
XP_005269621                                                           19     665
XP_006717704                                                           19     665
XP_005269619                                                           19     665
XP_005269618                                                           19     665
NP_001319                                                              18    1482
NP_001012632                                                           18    1482
XP_005272320                                                           18    1482
XP_005272319                                                           18    1482
XP_005272318                                                           18    1482
NP_665741                                                              16    5631
XP_005257067                                                           16    5631
NP_444256                                                              16    7355
NP_444254                                                              16    7355
NP_444253                                                              16    7355
NP_444255                                                              16    7355
NP_005076                                                              16    7355
NP_065928                                                              16    7355
XP_005256527                                                           16    7355
XP_005272276                                                           16    7355
XP_005272275                                                           16    7355
XP_006717355                                                           16    7355
XP_005272274                                                           16    7355
XP_005272273                                                           16    7355
XP_005247551                                                           16    7355
XP_005247550                                                           16    7355
XP_006713712                                                           16    7355
XP_005247549                                                           16    7355
NP_001004303                                                           15    9605
NP_689522                                                              15    9605
NP_003259                                                              15    9605
NP_079010                                                              15    9605
NP_001244299                                                           15    9605
XP_005255219                                                           15    9605
XP_006720319                                                           15    9605
XP_006718995                                                           15    9605
XP_005274425                                                           15    9605
XP_006718994                                                           15    9605
XP_006718993                                                           15    9605
XP_005274424                                                           15    9605
XP_005274423                                                           15    9605
XP_005269556                                                           15    9605
XP_005269555                                                           15    9605
XP_006711570                                                           15    9605
XP_006711569                                                           15    9605
XP_006711568                                                           15    9605
XP_005273300                                                           15    9605
XP_006711567                                                           15    9605
XP_006711566                                                           15    9605
XP_005273298                                                           15    9605
XP_005273299                                                           15    9605
XP_006710479                                                           15    9605
XP_005270641                                                           15    9605
XP_005270640                                                           15    9605
NP_203753                                                              15    9605
>NP_001277144
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>NP_001277143
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>NP_001077383
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>NP_001320
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>NP_073713
          Length = 985

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 839 ESEPFSFAQ 847
>XP_005269629
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_005269628
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_005269627
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_005269626
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_006717706
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_005269625
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_005269624
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_006717705
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_005269622
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_005269621
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_006717704
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_005269619
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>XP_005269618
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSFAQ
Sbjct: 299 ESEPFSFAQ 307
>NP_001319
          Length = 440

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSF+Q
Sbjct: 293 ESEPFSFSQ 301
>NP_001012632
          Length = 429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSF+Q
Sbjct: 282 ESEPFSFSQ 290
>XP_005272320
          Length = 430

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSF+Q
Sbjct: 282 ESEPFSFSQ 290
>XP_005272319
          Length = 430

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSF+Q
Sbjct: 282 ESEPFSFSQ 290
>XP_005272318
          Length = 441

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE FSF+Q
Sbjct: 293 ESEPFSFSQ 301
>NP_665741
          Length = 842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE+F+F Q
Sbjct: 592 ESENFAFWQ 600
>XP_005257067
          Length = 729

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESESFSFAQ 9
           ESE+F+F Q
Sbjct: 592 ESENFAFWQ 600
>NP_444256
          Length = 1794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ESESFSFAQ 9
           ESE F F Q
Sbjct: 596 ESEDFHFEQ 604
>NP_444254
          Length = 1845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ESESFSFAQ 9
           ESE F F Q
Sbjct: 596 ESEDFHFEQ 604
>NP_444253
          Length = 1914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ESESFSFAQ 9
           ESE F F Q
Sbjct: 665 ESEDFHFEQ 673
>NP_444255
          Length = 1863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ESESFSFAQ 9
           ESE F F Q
Sbjct: 665 ESEDFHFEQ 673
>NP_005076
          Length = 2090

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    SESFSFAQ 9
            S SFSF Q
Sbjct: 1781 SSSFSFGQ 1788
>NP_065928
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ESESFSFAQ 9
            ESESF+  Q
Sbjct: 1330 ESESFTLEQ 1338
>XP_005256527
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ESESFSFAQ 9
            ESESF+  Q
Sbjct: 1330 ESESFTLEQ 1338
>XP_005272276
          Length = 2036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    SESFSFAQ 9
            S SFSF Q
Sbjct: 1727 SSSFSFGQ 1734
>XP_005272275
          Length = 2083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    SESFSFAQ 9
            S SFSF Q
Sbjct: 1774 SSSFSFGQ 1781
>XP_006717355
          Length = 2120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    SESFSFAQ 9
            S SFSF Q
Sbjct: 1811 SSSFSFGQ 1818
>XP_005272274
          Length = 2121

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    SESFSFAQ 9
            S SFSF Q
Sbjct: 1812 SSSFSFGQ 1819
>XP_005272273
          Length = 2132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    SESFSFAQ 9
            S SFSF Q
Sbjct: 1823 SSSFSFGQ 1830
>XP_005247551
          Length = 1855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ESESFSFAQ 9
           ESE F F Q
Sbjct: 606 ESEDFHFEQ 614
>XP_005247550
          Length = 1856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ESESFSFAQ 9
           ESE F F Q
Sbjct: 675 ESEDFHFEQ 683
>XP_006713712
          Length = 1923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ESESFSFAQ 9
           ESE F F Q
Sbjct: 675 ESEDFHFEQ 683
>XP_005247549
          Length = 1924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ESESFSFAQ 9
           ESE F F Q
Sbjct: 675 ESEDFHFEQ 683
>NP_001004303
          Length = 728

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ESESFS 6
           ESESFS
Sbjct: 624 ESESFS 629
>NP_689522
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SESFSFAQ 9
           SESF F Q
Sbjct: 640 SESFRFQQ 647
>NP_003259
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESFSFAQ 9
           E+FS+AQ
Sbjct: 770 EAFSYAQ 776
>NP_079010
          Length = 1002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESESFSFAQ 9
           ES+ FS+ Q
Sbjct: 922 ESDHFSYVQ 930
>NP_001244299
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ESESFSF 7
           ES++FSF
Sbjct: 264 ESQAFSF 270
>XP_005255219
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ESESFSF 7
           ES++FSF
Sbjct: 236 ESQAFSF 242
>XP_006720319
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESESFSFAQ 9
           ES+ FS+ Q
Sbjct: 922 ESDHFSYVQ 930
>XP_006718995
          Length = 2382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ESESFSFAQ 9
            E E+F F+Q
Sbjct: 1047 EKEAFHFSQ 1055
>XP_005274425
          Length = 2566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ESESFSFAQ 9
            E E+F F+Q
Sbjct: 1280 EKEAFHFSQ 1288
>XP_006718994
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ESESFSFAQ 9
            E E+F F+Q
Sbjct: 1280 EKEAFHFSQ 1288
>XP_006718993
          Length = 2602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ESESFSFAQ 9
            E E+F F+Q
Sbjct: 1267 EKEAFHFSQ 1275
>XP_005274424
          Length = 2614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ESESFSFAQ 9
            E E+F F+Q
Sbjct: 1280 EKEAFHFSQ 1288
>XP_005274423
          Length = 2615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ESESFSFAQ 9
            E E+F F+Q
Sbjct: 1280 EKEAFHFSQ 1288
>XP_005269556
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SESFSFAQ 9
           SESF F Q
Sbjct: 462 SESFRFQQ 469
>XP_005269555
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SESFSFAQ 9
           SESF F Q
Sbjct: 462 SESFRFQQ 469
>XP_006711570
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESFSFAQ 9
           E+FS+AQ
Sbjct: 770 EAFSYAQ 776
>XP_006711569
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESFSFAQ 9
           E+FS+AQ
Sbjct: 770 EAFSYAQ 776
>XP_006711568
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESFSFAQ 9
           E+FS+AQ
Sbjct: 770 EAFSYAQ 776
>XP_005273300
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESFSFAQ 9
           E+FS+AQ
Sbjct: 770 EAFSYAQ 776
>XP_006711567
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESFSFAQ 9
           E+FS+AQ
Sbjct: 770 EAFSYAQ 776
>XP_006711566
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESFSFAQ 9
           E+FS+AQ
Sbjct: 770 EAFSYAQ 776
>XP_005273298
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESFSFAQ 9
           E+FS+AQ
Sbjct: 770 EAFSYAQ 776
>XP_005273299
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ESFSFAQ 9
           E+FS+AQ
Sbjct: 770 EAFSYAQ 776
>XP_006710479
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ESESFS 6
           ESESFS
Sbjct: 494 ESESFS 499
>XP_005270641
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ESESFS 6
           ESESFS
Sbjct: 516 ESESFS 521
>XP_005270640
          Length = 698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ESESFS 6
           ESESFS
Sbjct: 594 ESESFS 599
>NP_203753
          Length = 2601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ESESFSFAQ 9
            E E+F F+Q
Sbjct: 1267 EKEAFHFSQ 1275
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.110    0.262 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 447,018
Number of extensions: 675
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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