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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              19     869
NP_444254                                                              19     869
NP_444253                                                              19     869
NP_444255                                                              19     869
XP_005247551                                                           19     869
XP_005247550                                                           19     869
XP_006713712                                                           19     869
XP_005247549                                                           19     869
NP_851996                                                              16    5631
NP_001229537                                                           16    5631
NP_001070150                                                           16    5631
NP_001229536                                                           16    5631
NP_000606                                                              16    5631
NP_004420                                                              16    7355
NP_005042                                                              16    7355
NP_001259002                                                           16    7355
NP_004506                                                              16    7355
NP_001254738                                                           16    7355
NP_001071107                                                           15    9605
NP_060148                                                              15    9605
XP_005259057                                                           15    9605
XP_005259056                                                           15    9605
XP_006723307                                                           15    9605
XP_005259055                                                           15    9605
NP_059128                                                              15    9605

>NP_444256
          Length = 1794

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESDATVKMK 9
            ESDATVK K
Sbjct: 1148 ESDATVKKK 1156



>NP_444254
          Length = 1845

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESDATVKMK 9
            ESDATVK K
Sbjct: 1148 ESDATVKKK 1156



>NP_444253
          Length = 1914

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESDATVKMK 9
            ESDATVK K
Sbjct: 1217 ESDATVKKK 1225



>NP_444255
          Length = 1863

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESDATVKMK 9
            ESDATVK K
Sbjct: 1217 ESDATVKKK 1225



>XP_005247551
          Length = 1855

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESDATVKMK 9
            ESDATVK K
Sbjct: 1158 ESDATVKKK 1166



>XP_005247550
          Length = 1856

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESDATVKMK 9
            ESDATVK K
Sbjct: 1227 ESDATVKKK 1235



>XP_006713712
          Length = 1923

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESDATVKMK 9
            ESDATVK K
Sbjct: 1227 ESDATVKKK 1235



>XP_005247549
          Length = 1924

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESDATVKMK 9
            ESDATVK K
Sbjct: 1227 ESDATVKKK 1235



>NP_851996
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESDATVKMK 9
           ES+ATV +K
Sbjct: 105 ESEATVNVK 113




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESDATVKMK 9
           E DAT+ +K
Sbjct: 295 EQDATIHLK 303



>NP_001229537
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESDATVKMK 9
           ES+ATV +K
Sbjct: 105 ESEATVNVK 113




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESDATVKMK 9
           E DAT+ +K
Sbjct: 295 EQDATIHLK 303



>NP_001070150
          Length = 761

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESDATVKMK 9
           ES+ATV +K
Sbjct: 105 ESEATVNVK 113




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESDATVKMK 9
           E DAT+ +K
Sbjct: 295 EQDATIHLK 303



>NP_001229536
          Length = 884

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESDATVKMK 9
           ES+ATV +K
Sbjct: 105 ESEATVNVK 113




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESDATVKMK 9
           E DAT+ +K
Sbjct: 295 EQDATIHLK 303



>NP_000606
          Length = 848

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ESDATVKMK 9
           ES+ATV +K
Sbjct: 105 ESEATVNVK 113




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ESDATVKMK 9
           E DAT+ +K
Sbjct: 295 EQDATIHLK 303



>NP_004420
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ESDATVKM 8
           E+D TVKM
Sbjct: 184 EADNTVKM 191



>NP_005042
          Length = 775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ESDATVKMK 9
           E +AT++MK
Sbjct: 397 EGEATLRMK 405



>NP_001259002
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ESDATVKMK 9
           E +AT++MK
Sbjct: 386 EGEATLRMK 394



>NP_004506
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SDATVKM 8
           SDATVK+
Sbjct: 169 SDATVKI 175



>NP_001254738
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SDATVKM 8
           SDATVK+
Sbjct: 131 SDATVKI 137



>NP_001071107
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ATVKMK 9
           ATVKMK
Sbjct: 333 ATVKMK 338



>NP_060148
          Length = 260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ATVKMK 9
          ATVKMK
Sbjct: 49 ATVKMK 54



>XP_005259057
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDATVKMK 9
           SD+T K+K
Sbjct: 109 SDSTAKLK 116



>XP_005259056
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDATVKMK 9
           SD+T K+K
Sbjct: 109 SDSTAKLK 116



>XP_006723307
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDATVKMK 9
           SD+T K+K
Sbjct: 124 SDSTAKLK 131



>XP_005259055
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDATVKMK 9
           SD+T K+K
Sbjct: 124 SDSTAKLK 131



>NP_059128
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDATVKMK 9
           SD+T K+K
Sbjct: 109 SDSTAKLK 116



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293    0.106    0.242 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 428,745
Number of extensions: 787
Number of successful extensions: 30
Number of sequences better than 10000.0: 25
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)