Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
XP_006726436                                                           18    1482
XP_006726410                                                           18    1482
XP_006711784                                                           18    1482
XP_006711719                                                           18    1482
XP_006711718                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
XP_006711164                                                           18    1482
XP_005276153                                                           18    1482
XP_003846805                                                           18    1482
XP_006710122                                                           18    1482
NP_000341                                                              16    7355
NP_001004124                                                           16    7355
NP_001135451                                                           15    9605
NP_005648                                                              15    9605
NP_001135452                                                           15    9605
NP_060899                                                              15    9605
NP_009174                                                              15    9605
NP_001257638                                                           15    9605
NP_001257636                                                           15    9605
XP_006725524                                                           15    9605
XP_006725523                                                           15    9605
XP_005276828                                                           15    9605
XP_006726279                                                           15    9605
XP_006720729                                                           15    9605
XP_005254692                                                           15    9605
XP_005254691                                                           15    9605
XP_006716126                                                           15    9605
XP_005250566                                                           15    9605
XP_005250565                                                           15    9605
XP_006714722                                                           15    9605
XP_006714721                                                           15    9605
NP_001120829                                                           15    9605
NP_001120830                                                           15    9605
NP_065165                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2140 ESASLLTMF 2148
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2246 ESASLLTMF 2254
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2246 ESASLLTMF 2254
>XP_006726436
          Length = 178

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ESAFLLTMF 9
          ESA LLTMF
Sbjct: 24 ESASLLTMF 32
>XP_006726410
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 1987 ESASLLTMF 1995
>XP_006711784
          Length = 178

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ESAFLLTMF 9
          ESA LLTMF
Sbjct: 24 ESASLLTMF 32
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2202 ESASLLTMF 2210
>XP_006711718
          Length = 1436

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 1253 ESASLLTMF 1261
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2202 ESASLLTMF 2210
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2311 ESASLLTMF 2319
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2245 ESASLLTMF 2253
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2246 ESASLLTMF 2254
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2249 ESASLLTMF 2257
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2290 ESASLLTMF 2298
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2299 ESASLLTMF 2307
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2311 ESASLLTMF 2319
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2312 ESASLLTMF 2320
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2409 ESASLLTMF 2417
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2409 ESASLLTMF 2417
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2329 ESASLLTMF 2337
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2409 ESASLLTMF 2417
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2370 ESASLLTMF 2378
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2409 ESASLLTMF 2417
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2408 ESASLLTMF 2416
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 2409 ESASLLTMF 2417
>XP_006711164
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ESAFLLTMF 9
            ESA LLTMF
Sbjct: 1987 ESASLLTMF 1995
>XP_005276153
          Length = 267

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESAFLLTMF 9
           ESA LLTMF
Sbjct: 203 ESASLLTMF 211
>XP_003846805
          Length = 306

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ESAFLLTMF 9
           ESA LLTMF
Sbjct: 242 ESASLLTMF 250
>XP_006710122
          Length = 126

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ESAFLLTMF 9
          ESA LLTMF
Sbjct: 24 ESASLLTMF 32
>NP_000341
          Length = 2273

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAFLLTMF 9
           S FLLT+F
Sbjct: 711 SIFLLTIF 718
>NP_001004124
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAFLLTMF 9
           S FLLT+F
Sbjct: 156 SQFLLTIF 163
>NP_001135451
          Length = 1975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    AFLLTM 8
            AFLLTM
Sbjct: 1736 AFLLTM 1741
>NP_005648
          Length = 1972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    AFLLTM 8
            AFLLTM
Sbjct: 1733 AFLLTM 1738
>NP_001135452
          Length = 1977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    AFLLTM 8
            AFLLTM
Sbjct: 1738 AFLLTM 1743
>NP_060899
          Length = 2624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ESAFLLTM 8
            E AF+LT+
Sbjct: 2283 EQAFILTL 2290
>NP_009174
          Length = 262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AFLLTMF 9
           AFLLT++
Sbjct: 221 AFLLTLY 227
>NP_001257638
          Length = 203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AFLLTMF 9
           AFLLT++
Sbjct: 162 AFLLTLY 168
>NP_001257636
          Length = 268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AFLLTMF 9
           AFLLT++
Sbjct: 227 AFLLTLY 233
>XP_006725524
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ESAFLLTM 8
            E AF+LT+
Sbjct: 2283 EQAFILTL 2290
>XP_006725523
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ESAFLLTM 8
            E AF+LT+
Sbjct: 2282 EQAFILTL 2289
>XP_005276828
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ESAFLLTM 8
            E AF+LT+
Sbjct: 2283 EQAFILTL 2290
>XP_006726279
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ESAFLLTM 8
            E AF+LT+
Sbjct: 2282 EQAFILTL 2289
>XP_006720729
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AFLLTM 8
           AFLLTM
Sbjct: 701 AFLLTM 706
>XP_005254692
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AFLLTM 8
           AFLLTM
Sbjct: 778 AFLLTM 783
>XP_005254691
          Length = 1972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    AFLLTM 8
            AFLLTM
Sbjct: 1733 AFLLTM 1738
>XP_006716126
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SAFLLTM 8
           SAFLLT+
Sbjct: 561 SAFLLTI 567
>XP_005250566
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SAFLLTM 8
           SAFLLT+
Sbjct: 604 SAFLLTI 610
>XP_005250565
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SAFLLTM 8
           SAFLLT+
Sbjct: 604 SAFLLTI 610
>XP_006714722
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ESAFLLTM 8
            E AF+LT+
Sbjct: 2283 EQAFILTL 2290
>XP_006714721
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ESAFLLTM 8
            E AF+LT+
Sbjct: 2282 EQAFILTL 2289
>NP_001120829
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SAFLLTM 8
           SAFLLT+
Sbjct: 604 SAFLLTI 610
>NP_001120830
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SAFLLTM 8
           SAFLLT+
Sbjct: 600 SAFLLTI 606
>NP_065165
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SAFLLTM 8
           SAFLLT+
Sbjct: 600 SAFLLTI 606
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.142    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 293,058
Number of extensions: 400
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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