Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245200                                                           19     665
NP_000240                                                              19     665
XP_005265218                                                           19     665
NP_001139150                                                           17    4312
NP_775936                                                              17    4312
XP_006714651                                                           17    4312
NP_006057                                                              16    5631
NP_697021                                                              16    5631
NP_001189342                                                           16    5631
NP_001189343                                                           16    5631
NP_006447                                                              16    5631
NP_071737                                                              16    5631
NP_060754                                                              16    5631
NP_878905                                                              16    5631
XP_006713354                                                           16    5631
XP_005265446                                                           16    5631
XP_005265445                                                           16    5631
XP_005270801                                                           16    5631
XP_005270800                                                           16    5631
XP_005270799                                                           16    5631
XP_005270798                                                           16    5631
XP_006710637                                                           16    5631
NP_001128350                                                           16    5631
NP_001073991                                                           16    7355
NP_001122326                                                           16    7355
NP_001122324                                                           16    7355
NP_001122325                                                           16    7355
NP_056992                                                              16    7355
NP_059984                                                              16    7355
XP_006724893                                                           16    7355
XP_005274763                                                           16    7355
XP_006724892                                                           16    7355
XP_005274762                                                           16    7355
XP_006716086                                                           16    7355
XP_005250465                                                           16    7355
XP_005250464                                                           16    7355
XP_005250463                                                           16    7355
XP_005250462                                                           16    7355
XP_005248236                                                           16    7355
XP_005248234                                                           16    7355
NP_443187                                                              16    7355
>NP_001245200
          Length = 687

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ERFITSKLQ 9
          ERF TSKLQ
Sbjct: 78 ERFTTSKLQ 86
>NP_000240
          Length = 756

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ERFITSKLQ 9
          ERF TSKLQ
Sbjct: 78 ERFTTSKLQ 86
>XP_005265218
          Length = 687

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ERFITSKLQ 9
          ERF TSKLQ
Sbjct: 78 ERFTTSKLQ 86
>NP_001139150
          Length = 1275

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RFITSKLQ 9
           RF+ SKLQ
Sbjct: 170 RFLVSKLQ 177
>NP_775936
          Length = 324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RFITSKLQ 9
           RF+ SKLQ
Sbjct: 170 RFLVSKLQ 177
>XP_006714651
          Length = 1280

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RFITSKLQ 9
           RF+ SKLQ
Sbjct: 170 RFLVSKLQ 177
>NP_006057
          Length = 325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ERFITSKL 8
          E F+TSKL
Sbjct: 74 ELFVTSKL 81
>NP_697021
          Length = 325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ERFITSKL 8
          E F+TSKL
Sbjct: 74 ELFVTSKL 81
>NP_001189342
          Length = 325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ERFITSKL 8
          E F+TSKL
Sbjct: 74 ELFVTSKL 81
>NP_001189343
          Length = 325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ERFITSKL 8
          E F+TSKL
Sbjct: 74 ELFVTSKL 81
>NP_006447
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ERFITSKL 8
           ERF+ SKL
Sbjct: 285 ERFLKSKL 292
>NP_071737
          Length = 725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERFITSKL 8
           E++ITSK+
Sbjct: 234 EKYITSKI 241
>NP_060754
          Length = 595

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERFITSKLQ 9
           E+ +TSKLQ
Sbjct: 545 EKTLTSKLQ 553
>NP_878905
          Length = 790

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERFITSKL 8
           E++ITSK+
Sbjct: 234 EKYITSKI 241
>XP_006713354
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERFITSKL 8
           E++ITSK+
Sbjct: 192 EKYITSKI 199
>XP_005265446
          Length = 758

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERFITSKL 8
           E++ITSK+
Sbjct: 267 EKYITSKI 274
>XP_005265445
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERFITSKL 8
           E++ITSK+
Sbjct: 267 EKYITSKI 274
>XP_005270801
          Length = 461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERFITSKLQ 9
           E+ +TSKLQ
Sbjct: 411 EKTLTSKLQ 419
>XP_005270800
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERFITSKLQ 9
           E+ +TSKLQ
Sbjct: 466 EKTLTSKLQ 474
>XP_005270799
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERFITSKLQ 9
           E+ +TSKLQ
Sbjct: 466 EKTLTSKLQ 474
>XP_005270798
          Length = 544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERFITSKLQ 9
           E+ +TSKLQ
Sbjct: 518 EKTLTSKLQ 526
>XP_006710637
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ERFITSKLQ 9
           E+ +TSKLQ
Sbjct: 518 EKTLTSKLQ 526
>NP_001128350
          Length = 790

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ERFITSKL 8
           E++ITSK+
Sbjct: 234 EKYITSKI 241
>NP_001073991
          Length = 1620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RFITSKLQ 9
           +F+T KLQ
Sbjct: 448 KFLTDKLQ 455
>NP_001122326
          Length = 871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ERFITSKLQ 9
           E+F+TS  Q
Sbjct: 697 EKFVTSNTQ 705
>NP_001122324
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ERFITSKLQ 9
           E+F+TS  Q
Sbjct: 697 EKFVTSNTQ 705
>NP_001122325
          Length = 872

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ERFITSKLQ 9
           E+F+TS  Q
Sbjct: 698 EKFVTSNTQ 706
>NP_056992
          Length = 876

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ERFITSKLQ 9
           E+F+TS  Q
Sbjct: 698 EKFVTSNTQ 706
>NP_059984
          Length = 1871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ERFITSKL 8
           E+F TSK+
Sbjct: 255 EKFFTSKI 262
>XP_006724893
          Length = 1719

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ERFITSKL 8
           E+F TSK+
Sbjct: 255 EKFFTSKI 262
>XP_005274763
          Length = 1789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ERFITSKL 8
           E+F TSK+
Sbjct: 173 EKFFTSKI 180
>XP_006724892
          Length = 1841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ERFITSKL 8
           E+F TSK+
Sbjct: 255 EKFFTSKI 262
>XP_005274762
          Length = 1853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ERFITSKL 8
           E+F TSK+
Sbjct: 255 EKFFTSKI 262
>XP_006716086
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ERFITSKLQ 9
           E+F+TS  Q
Sbjct: 471 EKFVTSNTQ 479
>XP_005250465
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ERFITSKLQ 9
           E+F+TS  Q
Sbjct: 704 EKFVTSNTQ 712
>XP_005250464
          Length = 879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ERFITSKLQ 9
           E+F+TS  Q
Sbjct: 705 EKFVTSNTQ 713
>XP_005250463
          Length = 882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ERFITSKLQ 9
           E+F+TS  Q
Sbjct: 704 EKFVTSNTQ 712
>XP_005250462
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ERFITSKLQ 9
           E+F+TS  Q
Sbjct: 705 EKFVTSNTQ 713
>XP_005248236
          Length = 1262

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RFITSKLQ 9
           +F+T KLQ
Sbjct: 448 KFLTDKLQ 455
>XP_005248234
          Length = 1620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RFITSKLQ 9
           +F+T KLQ
Sbjct: 448 KFLTDKLQ 455
>NP_443187
          Length = 710

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ERFITS 6
           ERFITS
Sbjct: 174 ERFITS 179
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.134    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 336,565
Number of extensions: 455
Number of successful extensions: 41
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 41
Number of HSP's successfully gapped: 41
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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