Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004624                                                              16    5631
NP_001273575                                                           16    5631
NP_001073900                                                           16    5631
NP_002495                                                              16    5631
NP_001243257                                                           16    5631
NP_938406                                                              16    5631
NP_938191                                                              16    5631
NP_061496                                                              16    5631
NP_938197                                                              16    5631
NP_938200                                                              16    5631
NP_001243262                                                           16    5631
NP_938194                                                              16    5631
NP_001243289                                                           16    5631
NP_938202                                                              16    5631
NP_938199                                                              16    5631
NP_938192                                                              16    5631
NP_001243255                                                           16    5631
NP_938193                                                              16    5631
NP_001243290                                                           16    5631
NP_001243258                                                           16    5631
NP_001243254                                                           16    5631
NP_938201                                                              16    5631
NP_001243263                                                           16    5631
NP_001243261                                                           16    5631
NP_001243259                                                           16    5631
NP_938190                                                              16    5631
NP_938196                                                              16    5631
NP_938198                                                              16    5631
NP_001243256                                                           16    5631
NP_001243260                                                           16    5631
NP_001243288                                                           16    5631
NP_001243253                                                           16    5631
NP_667344                                                              16    5631
NP_001273577                                                           16    5631
XP_006722224                                                           16    5631
XP_006722223                                                           16    5631
XP_005251531                                                           16    5631
XP_005251530                                                           16    5631
XP_006716668                                                           16    5631
XP_006716667                                                           16    5631
XP_006712799                                                           16    5631
XP_006712798                                                           16    5631
XP_006712797                                                           16    5631
XP_006712796                                                           16    5631
NP_056436                                                              16    7355
NP_001018048                                                           15    9605
NP_056001                                                              15    9605
NP_001018047                                                           15    9605
NP_150648                                                              15    9605
NP_705838                                                              15    9605
NP_001018098                                                           15    9605
NP_060154                                                              15    9605
NP_060550                                                              15    9605
NP_065872                                                              15    9605
NP_003681                                                              15    9605
NP_055455                                                              15    9605
NP_065875                                                              15    9605
NP_002194                                                              15    9605
XP_005252604                                                           15    9605
XP_005252603                                                           15    9605
XP_005252601                                                           15    9605
XP_006717551                                                           15    9605
XP_005252600                                                           15    9605
XP_005252599                                                           15    9605
XP_006717550                                                           15    9605
XP_006712937                                                           15    9605
XP_006712936                                                           15    9605
XP_005247034                                                           15    9605
>NP_004624
          Length = 398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           +EASSTF
Sbjct: 342 KEASSTF 348
>NP_001273575
          Length = 808

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           R+ASSTF
Sbjct: 421 RQASSTF 427
>NP_001073900
          Length = 798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           R+ASSTF
Sbjct: 370 RQASSTF 376
>NP_002495
          Length = 1120

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EASSTFQ 9
           EASST+Q
Sbjct: 903 EASSTYQ 909
>NP_001243257
          Length = 2259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_938406
          Length = 2343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1142 EREAKSSF 1149
>NP_938191
          Length = 2366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_061496
          Length = 2377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_938197
          Length = 2306

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1142 EREAKSSF 1149
>NP_938200
          Length = 2266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243262
          Length = 2205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_938194
          Length = 2321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243289
          Length = 2248

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_938202
          Length = 2243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1142 EREAKSSF 1149
>NP_938199
          Length = 2332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_938192
          Length = 2273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243255
          Length = 2287

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_938193
          Length = 2298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1142 EREAKSSF 1149
>NP_001243290
          Length = 2246

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243258
          Length = 2250

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243254
          Length = 2291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_938201
          Length = 2250

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1142 EREAKSSF 1149
>NP_001243263
          Length = 2194

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243261
          Length = 2227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1142 EREAKSSF 1149
>NP_001243259
          Length = 2239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_938190
          Length = 2171

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1142 EREAKSSF 1149
>NP_938196
          Length = 2261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1142 EREAKSSF 1149
>NP_938198
          Length = 2284

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243256
          Length = 2277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243260
          Length = 2232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243288
          Length = 2257

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_001243253
          Length = 2314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1165 EREAKSSF 1172
>NP_667344
          Length = 1024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EASSTFQ 9
           EASST+Q
Sbjct: 903 EASSTYQ 909
>NP_001273577
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           R+ASSTF
Sbjct: 370 RQASSTF 376
>XP_006722224
          Length = 2244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1125 EREAKSSF 1132
>XP_006722223
          Length = 2268

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EREASSTF 8
            EREA S+F
Sbjct: 1142 EREAKSSF 1149
>XP_005251531
          Length = 1025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EASSTFQ 9
           EASST+Q
Sbjct: 904 EASSTYQ 910
>XP_005251530
          Length = 1121

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EASSTFQ 9
           EASST+Q
Sbjct: 904 EASSTYQ 910
>XP_006716668
          Length = 656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           R+ASSTF
Sbjct: 228 RQASSTF 234
>XP_006716667
          Length = 768

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           R+ASSTF
Sbjct: 421 RQASSTF 427
>XP_006712799
          Length = 423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           +EASSTF
Sbjct: 367 KEASSTF 373
>XP_006712798
          Length = 313

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           +EASSTF
Sbjct: 257 KEASSTF 263
>XP_006712797
          Length = 398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           +EASSTF
Sbjct: 342 KEASSTF 348
>XP_006712796
          Length = 402

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REASSTF 8
           +EASSTF
Sbjct: 346 KEASSTF 352
>NP_056436
          Length = 296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   REASSTFQ 9
           REASST Q
Sbjct: 124 REASSTQQ 131
>NP_001018048
          Length = 3069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 3017 ASSTFQ 3022
>NP_056001
          Length = 3095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 3017 ASSTFQ 3022
>NP_001018047
          Length = 3135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 2978 ASSTFQ 2983
>NP_150648
          Length = 3174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 3017 ASSTFQ 3022
>NP_705838
          Length = 4069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    EREASST 7
            EREASS+
Sbjct: 1139 EREASSS 1145
>NP_001018098
          Length = 3628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 3574 ASSTFQ 3579
>NP_060154
          Length = 3710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 3531 ASSTFQ 3536
>NP_060550
          Length = 3585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 3531 ASSTFQ 3536
>NP_065872
          Length = 3753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 3574 ASSTFQ 3579
>NP_003681
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  EREASSTF 8
          ERE S TF
Sbjct: 14 EREDSGTF 21
>NP_055455
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 1183 ASSTFQ 1188
>NP_065875
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EREASST 7
           ER+ASST
Sbjct: 788 ERKASST 794
>NP_002194
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 1085 ASSTFQ 1090
>XP_005252604
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EREASST 7
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005252603
          Length = 1457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EREASST 7
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005252601
          Length = 1948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EREASST 7
           ER+ASST
Sbjct: 778 ERKASST 784
>XP_006717551
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EREASST 7
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005252600
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EREASST 7
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_005252599
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EREASST 7
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_006717550
          Length = 1958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EREASST 7
           ER+ASST
Sbjct: 788 ERKASST 794
>XP_006712937
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 1183 ASSTFQ 1188
>XP_006712936
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 1183 ASSTFQ 1188
>XP_005247034
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ASSTFQ 9
            ASSTFQ
Sbjct: 1183 ASSTFQ 1188
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.105    0.243 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 396,095
Number of extensions: 557
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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