Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              19     869
NP_001087241                                                           19     869
NP_004110                                                              19     869
XP_005265799                                                           19     869
XP_005265798                                                           19     869
XP_005265797                                                           19     869
NP_005202                                                              18    1935
NP_001275634                                                           18    1935
NP_702918                                                              18    1935
NP_702915                                                              18    1935
NP_702911                                                              18    1935
NP_001229282                                                           18    1935
NP_001229281                                                           18    1935
NP_001229283                                                           18    1935
NP_002531                                                              18    1935
NP_702914                                                              18    1935
NP_702913                                                              18    1935
NP_702910                                                              18    1935
NP_702917                                                              18    1935
XP_006717191                                                           18    1935
XP_006717190                                                           18    1935
XP_005252086                                                           18    1935
XP_005252085                                                           18    1935
XP_006717189                                                           18    1935
XP_006717188                                                           18    1935
XP_005252084                                                           18    1935
XP_005252083                                                           18    1935
XP_005252082                                                           18    1935
XP_006717187                                                           18    1935
XP_005252081                                                           18    1935
XP_005252080                                                           18    1935
XP_005252079                                                           18    1935
XP_005252078                                                           18    1935
XP_006717186                                                           18    1935
XP_005252077                                                           18    1935
XP_005252075                                                           18    1935
XP_005252076                                                           18    1935
XP_005252074                                                           18    1935
XP_005252073                                                           18    1935
XP_006717185                                                           18    1935
XP_005252072                                                           18    1935
XP_005252071                                                           18    1935
XP_005252070                                                           18    1935
XP_005252069                                                           18    1935
XP_005252068                                                           18    1935
XP_005252067                                                           18    1935
NP_891989                                                              17    4312
NP_065972                                                              17    4312
NP_891991                                                              17    4312
NP_003557                                                              17    4312
NP_002966                                                              17    4312
XP_006720223                                                           17    4312
XP_006719694                                                           17    4312
NP_056416                                                              15    9605
NP_001265115                                                           15    9605
NP_001265114                                                           15    9605
XP_006717815                                                           15    9605
XP_006717814                                                           15    9605
NP_071362                                                              15    9605
>NP_000213
          Length = 976

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           EREALMS+L
Sbjct: 633 EREALMSEL 641
>NP_001087241
          Length = 972

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           EREALMS+L
Sbjct: 629 EREALMSEL 637
>NP_004110
          Length = 993

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           EREALMS+L
Sbjct: 654 EREALMSEL 662
>XP_005265799
          Length = 973

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           EREALMS+L
Sbjct: 630 EREALMSEL 638
>XP_005265798
          Length = 976

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           EREALMS+L
Sbjct: 634 EREALMSEL 642
>XP_005265797
          Length = 977

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           EREALMS+L
Sbjct: 634 EREALMSEL 642
>NP_005202
          Length = 972

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           E+EALMS+L
Sbjct: 626 EKEALMSEL 634
>NP_001275634
          Length = 972

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           E+EALMS+L
Sbjct: 626 EKEALMSEL 634
>NP_702918
          Length = 638

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 184 EKECLMSKL 192
>NP_702915
          Length = 638

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 184 EKECLMSKL 192
>NP_702911
          Length = 829

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>NP_001229282
          Length = 829

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>NP_001229281
          Length = 824

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 198 EKECLMSKL 206
>NP_001229283
          Length = 576

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 122 EKECLMSKL 130
>NP_002531
          Length = 805

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 179 EKECLMSKL 187
>NP_702914
          Length = 657

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>NP_702913
          Length = 893

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 267 EKECLMSKL 275
>NP_702910
          Length = 701

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 247 EKECLMSKL 255
>NP_702917
          Length = 653

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 228 EKECLMSKL 236
>XP_006717191
          Length = 657

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>XP_006717190
          Length = 805

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 179 EKECLMSKL 187
>XP_005252086
          Length = 810

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 184 EKECLMSKL 192
>XP_005252085
          Length = 819

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 141 EKECLMSKL 149
>XP_006717189
          Length = 829

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>XP_006717188
          Length = 854

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 228 EKECLMSKL 236
>XP_005252084
          Length = 857

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 179 EKECLMSKL 187
>XP_005252083
          Length = 857

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 179 EKECLMSKL 187
>XP_005252082
          Length = 862

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 184 EKECLMSKL 192
>XP_006717187
          Length = 862

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 184 EKECLMSKL 192
>XP_005252081
          Length = 862

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 184 EKECLMSKL 192
>XP_005252080
          Length = 862

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 184 EKECLMSKL 192
>XP_005252079
          Length = 862

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 184 EKECLMSKL 192
>XP_005252078
          Length = 868

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 190 EKECLMSKL 198
>XP_006717186
          Length = 873

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 247 EKECLMSKL 255
>XP_005252077
          Length = 876

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 198 EKECLMSKL 206
>XP_005252075
          Length = 876

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 198 EKECLMSKL 206
>XP_005252076
          Length = 876

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 198 EKECLMSKL 206
>XP_005252074
          Length = 876

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 198 EKECLMSKL 206
>XP_005252073
          Length = 881

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>XP_006717185
          Length = 881

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>XP_005252072
          Length = 881

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>XP_005252071
          Length = 881

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>XP_005252070
          Length = 881

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>XP_005252069
          Length = 881

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 203 EKECLMSKL 211
>XP_005252068
          Length = 906

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 228 EKECLMSKL 236
>XP_005252067
          Length = 925

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           E+E LMSKL
Sbjct: 247 EKECLMSKL 255
>NP_891989
          Length = 2046

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           ER+ +MSKL
Sbjct: 979 ERQEMMSKL 987
>NP_065972
          Length = 2133

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           ER+ +MSKL
Sbjct: 979 ERQEMMSKL 987
>NP_891991
          Length = 2090

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           ER+ +MSKL
Sbjct: 979 ERQEMMSKL 987
>NP_003557
          Length = 1411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           E+EALM++L
Sbjct: 847 EKEALMTEL 855
>NP_002966
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EREALMSK 8
          EREALM K
Sbjct: 42 EREALMLK 49
>XP_006720223
          Length = 1989

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EREALMSKL 9
           ER+ +MSKL
Sbjct: 979 ERQEMMSKL 987
>XP_006719694
          Length = 1465

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   EREALMSKL 9
           E+EALM++L
Sbjct: 901 EKEALMTEL 909
>NP_056416
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EREALMSKL 9
            E+E L SKL
Sbjct: 1028 EKETLRSKL 1036
>NP_001265115
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EREALMSKL 9
           E+E L SKL
Sbjct: 773 EKETLRSKL 781
>NP_001265114
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EREALMSKL 9
           E+E L SKL
Sbjct: 958 EKETLRSKL 966
>XP_006717815
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EREALMSKL 9
           E+E L SKL
Sbjct: 915 EKETLRSKL 923
>XP_006717814
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EREALMSKL 9
            E+E L SKL
Sbjct: 1036 EKETLRSKL 1044
>NP_071362
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EREALMSKL 9
            E+E L SKL
Sbjct: 1036 EKETLRSKL 1044
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.121    0.274 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 315,832
Number of extensions: 422
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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