Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1482
XP_006718908                                                           18    1482
XP_005271621                                                           18    1482
XP_006718907                                                           18    1482
XP_006718906                                                           18    1482
XP_005271619                                                           18    1482
XP_005271618                                                           18    1482
NP_005890                                                              17    3301
NP_114068                                                              17    3301
NP_114064                                                              17    3301
NP_001123572                                                           17    4312
NP_001123571                                                           17    4312
NP_005541                                                              17    4312
XP_006721253                                                           17    4312
XP_005256003                                                           17    4312
XP_005256002                                                           17    4312
XP_005256001                                                           17    4312
XP_006721252                                                           17    4312
XP_005256000                                                           17    4312
XP_005255994                                                           17    4312
XP_006721251                                                           17    4312
NP_004299                                                              16    5631
NP_001167574                                                           16    7355
NP_002910                                                              15    9605
NP_001269046                                                           15    9605
NP_602304                                                              15    9605
NP_001269045                                                           15    9605
NP_001106197                                                           15    9605
NP_689777                                                              15    9605
NP_060360                                                              15    9605
NP_055820                                                              15    9605
NP_001034485                                                           15    9605
NP_056502                                                              15    9605
NP_001276916                                                           15    9605
XP_006721018                                                           15    9605
XP_005267607                                                           15    9605
XP_006716909                                                           15    9605
XP_005251591                                                           15    9605
XP_006716908                                                           15    9605
XP_006716907                                                           15    9605
XP_006716906                                                           15    9605
XP_006716905                                                           15    9605
XP_006716904                                                           15    9605
XP_006716903                                                           15    9605
XP_005250858                                                           15    9605
XP_005250857                                                           15    9605
XP_005248772                                                           15    9605
XP_005248771                                                           15    9605
XP_005248770                                                           15    9605
XP_005247884                                                           15    9605
XP_005247883                                                           15    9605
XP_005247882                                                           15    9605
XP_005247881                                                           15    9605
XP_005247880                                                           15    9605
NP_114436                                                              15    9605
NP_005633                                                              15    9605
>NP_000042
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQVGVQKQV 9
            EQV VQKQV
Sbjct: 1530 EQVEVQKQV 1538
>XP_006718908
          Length = 1708

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV VQKQV
Sbjct: 182 EQVEVQKQV 190
>XP_005271621
          Length = 2708

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQVGVQKQV 9
            EQV VQKQV
Sbjct: 1182 EQVEVQKQV 1190
>XP_006718907
          Length = 3050

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQVGVQKQV 9
            EQV VQKQV
Sbjct: 1524 EQVEVQKQV 1532
>XP_006718906
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQVGVQKQV 9
            EQV VQKQV
Sbjct: 1530 EQVEVQKQV 1538
>XP_005271619
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQVGVQKQV 9
            EQV VQKQV
Sbjct: 1530 EQVEVQKQV 1538
>XP_005271618
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQVGVQKQV 9
            EQV VQKQV
Sbjct: 1530 EQVEVQKQV 1538
>NP_005890
          Length = 966

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +QKQV
Sbjct: 285 EQVRLQKQV 293
>NP_114068
          Length = 966

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +QKQV
Sbjct: 285 EQVRLQKQV 293
>NP_114064
          Length = 966

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +QKQV
Sbjct: 285 EQVRLQKQV 293
>NP_001123572
          Length = 826

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 284 EQVAMQRQV 292
>NP_001123571
          Length = 687

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 145 EQVAMQRQV 153
>NP_005541
          Length = 833

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 284 EQVAMQRQV 292
>XP_006721253
          Length = 828

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 279 EQVAMQRQV 287
>XP_005256003
          Length = 768

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 226 EQVAMQRQV 234
>XP_005256002
          Length = 769

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 227 EQVAMQRQV 235
>XP_005256001
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 226 EQVAMQRQV 234
>XP_006721252
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 226 EQVAMQRQV 234
>XP_005256000
          Length = 776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 227 EQVAMQRQV 235
>XP_005255994
          Length = 996

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 447 EQVAMQRQV 455
>XP_006721251
          Length = 1022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+QV
Sbjct: 473 EQVAMQRQV 481
>NP_004299
          Length = 439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQ+G+ +QV
Sbjct: 202 EQLGIPRQV 210
>NP_001167574
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           E+V +Q+Q+
Sbjct: 154 EEVSIQRQI 162
>NP_002910
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 32 QQVPVQQQV 40
>NP_001269046
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 32 QQVPVQQQV 40
>NP_602304
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 32 QQVPVQQQV 40
>NP_001269045
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 32 QQVPVQQQV 40
>NP_001106197
          Length = 1554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+Q+
Sbjct: 382 EQVRLQRQI 390
>NP_689777
          Length = 3997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    GVQKQV 9
            GVQKQ+
Sbjct: 2695 GVQKQI 2700
>NP_060360
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    GVQKQV 9
            GVQKQ+
Sbjct: 2720 GVQKQI 2725
>NP_055820
          Length = 1519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+Q+
Sbjct: 312 EQVRLQRQI 320
>NP_001034485
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  EQVGVQK 7
          ++VGVQK
Sbjct: 27 DEVGVQK 33
>NP_056502
          Length = 1213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EQVGVQKQ 8
           EQ+G+Q Q
Sbjct: 259 EQLGLQSQ 266
>NP_001276916
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EQVGVQKQ 8
           EQ+G+Q Q
Sbjct: 262 EQLGLQSQ 269
>XP_006721018
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EQVGVQKQ 8
           E+VGVQ++
Sbjct: 390 EEVGVQQR 397
>XP_005267607
          Length = 1589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EQVGVQKQV 9
           EQV +Q+Q+
Sbjct: 382 EQVRLQRQI 390
>XP_006716909
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 38 QQVPVQQQV 46
>XP_005251591
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 42 QQVPVQQQV 50
>XP_006716908
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 32 QQVPVQQQV 40
>XP_006716907
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 32 QQVPVQQQV 40
>XP_006716906
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 32 QQVPVQQQV 40
>XP_006716905
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 32 QQVPVQQQV 40
>XP_006716904
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 38 QQVPVQQQV 46
>XP_006716903
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EQVGVQKQV 9
          +QV VQ+QV
Sbjct: 42 QQVPVQQQV 50
>XP_005250858
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    GVQKQV 9
            GVQKQ+
Sbjct: 2720 GVQKQI 2725
>XP_005250857
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    GVQKQV 9
            GVQKQ+
Sbjct: 2720 GVQKQI 2725
>XP_005248772
          Length = 1154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EQVGVQKQ 8
           EQ+G+Q Q
Sbjct: 259 EQLGLQSQ 266
>XP_005248771
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EQVGVQKQ 8
           EQ+G+Q Q
Sbjct: 259 EQLGLQSQ 266
>XP_005248770
          Length = 1213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EQVGVQKQ 8
           EQ+G+Q Q
Sbjct: 259 EQLGLQSQ 266
>XP_005247884
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EQVGVQ 6
           EQ+GVQ
Sbjct: 211 EQIGVQ 216
>XP_005247883
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EQVGVQ 6
           EQ+GVQ
Sbjct: 211 EQIGVQ 216
>XP_005247882
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EQVGVQ 6
           EQ+GVQ
Sbjct: 211 EQIGVQ 216
>XP_005247881
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EQVGVQ 6
           EQ+GVQ
Sbjct: 211 EQIGVQ 216
>XP_005247880
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EQVGVQ 6
           EQ+GVQ
Sbjct: 211 EQIGVQ 216
>NP_114436
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EQVGVQ 6
           EQ+GVQ
Sbjct: 211 EQIGVQ 216
>NP_005633
          Length = 349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VGVQKQV 9
           +G+QKQ+
Sbjct: 279 MGIQKQI 285
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.124    0.299 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 500,035
Number of extensions: 939
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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