Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              20     390
NP_001035957                                                           20     390
XP_006721990                                                           20     390
XP_006721989                                                           20     390
XP_005258041                                                           20     390
XP_006721988                                                           20     390
XP_006721987                                                           20     390
XP_006721986                                                           20     390
XP_005258040                                                           20     390
XP_006721985                                                           20     390
NP_005984                                                              17    2528
XP_006722353                                                           17    2528
XP_005256453                                                           17    2528
NP_066933                                                              16    5631
NP_057314                                                              16    5631
NP_002220                                                              16    5631
NP_115606                                                              16    5631
XP_005269243                                                           16    5631
XP_006719700                                                           16    5631
XP_005269242                                                           16    5631
XP_006719699                                                           16    5631
XP_005269241                                                           16    5631
XP_005251116                                                           16    5631
XP_006716714                                                           16    5631
NP_055317                                                              16    7355
NP_071349                                                              16    7355
NP_001231627                                                           16    7355
NP_004917                                                              16    7355
NP_001177739                                                           16    7355
NP_001231630                                                           16    7355
XP_005257625                                                           16    7355
XP_005257624                                                           16    7355
XP_006716812                                                           16    7355
NP_001849                                                              15    9605
NP_000570                                                              15    9605
NP_001093638                                                           15    9605
NP_780775                                                              15    9605
NP_001230199                                                           15    9605
NP_055176                                                              15    9605
NP_631918                                                              15    9605
NP_001073869                                                           15    9605
XP_006726460                                                           15    9605
XP_006722933                                                           15    9605
XP_006722932                                                           15    9605
XP_006722931                                                           15    9605
XP_006722930                                                           15    9605
XP_005259697                                                           15    9605
XP_006722929                                                           15    9605
XP_005275982                                                           15    9605
>NP_000258
          Length = 2818

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1673 ERLLTGLKG 1681
>NP_001035957
          Length = 2839

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1694 ERLLTGLKG 1702
>XP_006721990
          Length = 2823

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1704 ERLLTGLKG 1712
>XP_006721989
          Length = 2823

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1704 ERLLTGLKG 1712
>XP_005258041
          Length = 2836

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1673 ERLLTGLKG 1681
>XP_006721988
          Length = 2846

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1683 ERLLTGLKG 1691
>XP_006721987
          Length = 2849

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1704 ERLLTGLKG 1712
>XP_006721986
          Length = 2854

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1691 ERLLTGLKG 1699
>XP_005258040
          Length = 2857

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1694 ERLLTGLKG 1702
>XP_006721985
          Length = 2867

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQLLTGLKG 9
            E+LLTGLKG
Sbjct: 1704 ERLLTGLKG 1712
>NP_005984
          Length = 1192

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   EQLLTGLK 8
           EQLL GLK
Sbjct: 363 EQLLVGLK 370
>XP_006722353
          Length = 1165

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   EQLLTGLK 8
           EQLL GLK
Sbjct: 363 EQLLVGLK 370
>XP_005256453
          Length = 1175

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   EQLLTGLK 8
           EQLL GLK
Sbjct: 346 EQLLVGLK 353
>NP_066933
          Length = 1796

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EQLLTGLKG 9
            E+ LTG+KG
Sbjct: 1691 ERGLTGIKG 1699
>NP_057314
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LTGLKG 9
          LTGLKG
Sbjct: 47 LTGLKG 52
>NP_002220
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLLTGLKG 9
           QLL G+KG
Sbjct: 337 QLLLGVKG 344
>NP_115606
          Length = 603

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQLLTGLKG 9
           EQLL  L+G
Sbjct: 127 EQLLVALRG 135
>XP_005269243
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQLLTGLKG 9
           EQLL  L+G
Sbjct: 127 EQLLVALRG 135
>XP_006719700
          Length = 468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQLLTGLKG 9
           EQLL  L+G
Sbjct: 127 EQLLVALRG 135
>XP_005269242
          Length = 508

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQLLTGLKG 9
           EQLL  L+G
Sbjct: 127 EQLLVALRG 135
>XP_006719699
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EQLLTGLKG 9
          EQLL  L+G
Sbjct: 40 EQLLVALRG 48
>XP_005269241
          Length = 547

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQLLTGLKG 9
           EQLL  L+G
Sbjct: 127 EQLLVALRG 135
>XP_005251116
          Length = 1780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EQLLTGLKG 9
            E+ LTG+KG
Sbjct: 1691 ERGLTGIKG 1699
>XP_006716714
          Length = 1796

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EQLLTGLKG 9
            E+ LTG+KG
Sbjct: 1691 ERGLTGIKG 1699
>NP_055317
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQLLTGLKG 9
           EQ+L  LKG
Sbjct: 254 EQILATLKG 262
>NP_071349
          Length = 1292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EQLLTG 6
           EQLLTG
Sbjct: 830 EQLLTG 835
>NP_001231627
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QLLTGLKG 9
          QLL+ LKG
Sbjct: 66 QLLSSLKG 73
>NP_004917
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QLLTGLKG 9
          QLL+ LKG
Sbjct: 66 QLLSSLKG 73
>NP_001177739
          Length = 658

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EQLLTG 6
           EQLLTG
Sbjct: 640 EQLLTG 645
>NP_001231630
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLLTGLKG 9
           QLL+ LKG
Sbjct: 135 QLLSSLKG 142
>XP_005257625
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EQLLTG 6
           EQLLTG
Sbjct: 806 EQLLTG 811
>XP_005257624
          Length = 1293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EQLLTG 6
           EQLLTG
Sbjct: 831 EQLLTG 836
>XP_006716812
          Length = 1074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    EQLLTGLK 8
            EQ++TG K
Sbjct: 1013 EQIITGTK 1020
>NP_001849
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LTGLKG 9
           LTG+KG
Sbjct: 972 LTGMKG 977
>NP_000570
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QLLTGL 7
           QLLTGL
Sbjct: 102 QLLTGL 107
>NP_001093638
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QLLTGL 7
           QLLTGL
Sbjct: 102 QLLTGL 107
>NP_780775
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLTGLKG 9
           +LTGL+G
Sbjct: 862 ILTGLEG 868
>NP_001230199
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLTGLKG 9
           +LTGL+G
Sbjct: 936 ILTGLEG 942
>NP_055176
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLTGLKG 9
           +LTGL+G
Sbjct: 936 ILTGLEG 942
>NP_631918
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QLLTGLK 8
           QLL GLK
Sbjct: 180 QLLNGLK 186
>NP_001073869
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EQLLTGLK 8
            EQLL GL+
Sbjct: 1331 EQLLEGLQ 1338
>XP_006726460
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QLLTGL 7
           QLLTGL
Sbjct: 215 QLLTGL 220
>XP_006722933
          Length = 1240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EQLLTGLK 8
            EQLL GL+
Sbjct: 1214 EQLLEGLQ 1221
>XP_006722932
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EQLLTGLK 8
            EQLL GL+
Sbjct: 1280 EQLLEGLQ 1287
>XP_006722931
          Length = 1371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EQLLTGLK 8
            EQLL GL+
Sbjct: 1345 EQLLEGLQ 1352
>XP_006722930
          Length = 1372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EQLLTGLK 8
            EQLL GL+
Sbjct: 1346 EQLLEGLQ 1353
>XP_005259697
          Length = 1372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EQLLTGLK 8
            EQLL GL+
Sbjct: 1346 EQLLEGLQ 1353
>XP_006722929
          Length = 1372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EQLLTGLK 8
            EQLL GL+
Sbjct: 1346 EQLLEGLQ 1353
>XP_005275982
          Length = 187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QLLTGL 7
           QLLTGL
Sbjct: 155 QLLTGL 160
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.140    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 507,002
Number of extensions: 1307
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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