Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060427                                                              18    1482
NP_001185761                                                           18    1935
NP_001185763                                                           18    1935
NP_055459                                                              18    1935
XP_006726410                                                           18    1935
XP_006711719                                                           18    1935
XP_006711718                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711712                                                           18    1935
XP_006711711                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
XP_005277503                                                           18    1935
XP_005273038                                                           18    1935
XP_006711708                                                           18    1935
XP_005277500                                                           18    1935
XP_006711707                                                           18    1935
XP_005277499                                                           18    1935
XP_006711706                                                           18    1935
XP_006711705                                                           18    1935
XP_006711164                                                           18    1935
XP_006710143                                                           18    1935
XP_006710142                                                           18    1935
XP_006710141                                                           18    1935
NP_001269903                                                           17    4312
NP_001269900                                                           17    4312
NP_055566                                                              17    4312
XP_006716769                                                           17    4312
XP_005251175                                                           17    4312
XP_006716768                                                           17    4312
XP_006716767                                                           17    4312
XP_006716766                                                           17    4312
XP_005251170                                                           17    4312
XP_006716765                                                           17    4312
XP_006716764                                                           17    4312
XP_006716763                                                           17    4312
XP_005251168                                                           17    4312
XP_005258887                                                           16    7355
XP_005258886                                                           16    7355
XP_006723240                                                           16    7355
XP_006723239                                                           16    7355
NP_001123544                                                           16    7355
NP_001121186                                                           15    9605
NP_078779                                                              15    9605
NP_006725                                                              15    9605
XP_006723058                                                           15    9605
XP_005267014                                                           15    9605
XP_006710872                                                           15    9605
XP_006710871                                                           15    9605
NP_001073903                                                           15    9605
NP_006811                                                              15    9605
>NP_060427
          Length = 632

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QLALRLSR 9
           QLALRLSR
Sbjct: 242 QLALRLSR 249
>NP_001185761
          Length = 2240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1519 EPLALRLSR 1527
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1563 EPLALRLSR 1571
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1563 EPLALRLSR 1571
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1366 EPLALRLSR 1374
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1519 EPLALRLSR 1527
>XP_006711718
          Length = 1436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E LALRLSR
Sbjct: 570 EPLALRLSR 578
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1519 EPLALRLSR 1527
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1628 EPLALRLSR 1636
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1562 EPLALRLSR 1570
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1563 EPLALRLSR 1571
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1566 EPLALRLSR 1574
>XP_006711712
          Length = 2473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1726 EPLALRLSR 1734
>XP_006711711
          Length = 2482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1616 EPLALRLSR 1624
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1628 EPLALRLSR 1636
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1629 EPLALRLSR 1637
>XP_005277503
          Length = 2498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1726 EPLALRLSR 1734
>XP_005273038
          Length = 2509

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1726 EPLALRLSR 1734
>XP_006711708
          Length = 2512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1726 EPLALRLSR 1734
>XP_005277500
          Length = 2525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1726 EPLALRLSR 1734
>XP_006711707
          Length = 2553

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1726 EPLALRLSR 1734
>XP_005277499
          Length = 2561

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1726 EPLALRLSR 1734
>XP_006711706
          Length = 2591

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1725 EPLALRLSR 1733
>XP_006711705
          Length = 2592

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1726 EPLALRLSR 1734
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EQLALRLSR 9
            E LALRLSR
Sbjct: 1366 EPLALRLSR 1374
>XP_006710143
          Length = 562

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E LALRLSR
Sbjct: 405 EPLALRLSR 413
>XP_006710142
          Length = 671

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E LALRLSR
Sbjct: 514 EPLALRLSR 522
>XP_006710141
          Length = 672

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E LALRLSR
Sbjct: 515 EPLALRLSR 523
>NP_001269903
          Length = 730

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 452 EELALALSR 460
>NP_001269900
          Length = 759

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 481 EELALALSR 489
>NP_055566
          Length = 755

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 477 EELALALSR 485
>XP_006716769
          Length = 677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 399 EELALALSR 407
>XP_005251175
          Length = 694

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 416 EELALALSR 424
>XP_006716768
          Length = 742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 464 EELALALSR 472
>XP_006716767
          Length = 758

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 480 EELALALSR 488
>XP_006716766
          Length = 786

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 508 EELALALSR 516
>XP_005251170
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 525 EELALALSR 533
>XP_006716765
          Length = 851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 573 EELALALSR 581
>XP_006716764
          Length = 864

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 586 EELALALSR 594
>XP_006716763
          Length = 867

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 589 EELALALSR 597
>XP_005251168
          Length = 868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EQLALRLSR 9
           E+LAL LSR
Sbjct: 590 EELALALSR 598
>XP_005258887
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QLALRLSR 9
           QLAL LSR
Sbjct: 214 QLALSLSR 221
>XP_005258886
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QLALRLSR 9
           QLAL LSR
Sbjct: 214 QLALSLSR 221
>XP_006723240
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QLALRLSR 9
           QLAL LSR
Sbjct: 274 QLALSLSR 281
>XP_006723239
          Length = 636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QLALRLSR 9
           QLAL LSR
Sbjct: 274 QLALSLSR 281
>NP_001123544
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QLALRLSR 9
           QLAL LSR
Sbjct: 214 QLALSLSR 221
>NP_001121186
          Length = 2405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EQLALRLS 8
           ++LALRLS
Sbjct: 362 QKLALRLS 369
>NP_078779
          Length = 2406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EQLALRLS 8
           ++LALRLS
Sbjct: 362 QKLALRLS 369
>NP_006725
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EQLALRLS 8
           ++LALRLS
Sbjct: 367 QKLALRLS 374
>XP_006723058
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EQLALRLSR 9
            EQ+  RLSR
Sbjct: 1222 EQIKARLSR 1230
>XP_005267014
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EQLALRLS 8
           ++LALRLS
Sbjct: 367 QKLALRLS 374
>XP_006710872
          Length = 1590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EQLALRLS 8
           ++LALRLS
Sbjct: 362 QKLALRLS 369
>XP_006710871
          Length = 2406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EQLALRLS 8
           ++LALRLS
Sbjct: 362 QKLALRLS 369
>NP_001073903
          Length = 1489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EQLALRLSR 9
            EQ+  RLSR
Sbjct: 1251 EQIKARLSR 1259
>NP_006811
          Length = 452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQLALRLSR 9
           EQL  RLS+
Sbjct: 110 EQLVCRLSK 118
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.134    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 311,301
Number of extensions: 418
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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