Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     390
NP_001075109                                                           20     390
NP_203748                                                              17    3301
XP_005271772                                                           17    3301
NP_000487                                                              17    4312
NP_982272                                                              17    4312
NP_001177387                                                           17    4312
NP_001180465                                                           17    4312
NP_055325                                                              17    4312
NP_149015                                                              17    4312
XP_006724204                                                           17    4312
XP_006715989                                                           17    4312
NP_001160135                                                           16    5631
NP_072179                                                              16    7355
NP_002881                                                              16    7355
NP_055855                                                              16    7355
NP_001193581                                                           16    7355
NP_057093                                                              16    7355
NP_001193580                                                           16    7355
NP_006156                                                              16    7355
XP_005271626                                                           16    7355
XP_005271625                                                           16    7355
XP_005271624                                                           16    7355
XP_005271622                                                           16    7355
XP_006712426                                                           16    7355
XP_006712425                                                           16    7355
XP_006712424                                                           16    7355
XP_006710735                                                           16    7355
NP_060552                                                              15    9605
NP_996809                                                              15    9605
NP_065184                                                              15    9605
NP_112503                                                              15    9605
NP_000094                                                              15    9605
NP_078959                                                              15    9605
NP_001231892                                                           15    9605
NP_001154180                                                           15    9605
NP_001104488                                                           15    9605
NP_001104489                                                           15    9605
NP_795352                                                              15    9605
NP_057422                                                              15    9605
NP_660093                                                              15    9605
NP_892009                                                              15    9605
XP_006722147                                                           15    9605
XP_006720469                                                           15    9605
XP_005254249                                                           15    9605
XP_005254248                                                           15    9605
XP_005254247                                                           15    9605
XP_006719561                                                           15    9605
XP_006718432                                                           15    9605
XP_005253271                                                           15    9605
XP_006718431                                                           15    9605
XP_006718430                                                           15    9605
XP_006718429                                                           15    9605
XP_006718428                                                           15    9605
XP_006718427                                                           15    9605
XP_006710341                                                           15    9605
XP_005270404                                                           15    9605
XP_005270402                                                           15    9605
XP_005270400                                                           15    9605
XP_006710340                                                           15    9605
XP_005270398                                                           15    9605
XP_006710339                                                           15    9605
XP_006710338                                                           15    9605
NP_001128251                                                           15    9605
>NP_008835
          Length = 4128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQFVFESLV 9
            EQFVFE+LV
Sbjct: 1097 EQFVFEALV 1105
>NP_001075109
          Length = 4097

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EQFVFESLV 9
            EQFVFE+LV
Sbjct: 1097 EQFVFEALV 1105
>NP_203748
          Length = 883

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           EQF F+SL
Sbjct: 805 EQFTFQSL 812
>XP_005271772
          Length = 884

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           EQF F+SL
Sbjct: 806 EQFTFQSL 813
>NP_000487
          Length = 205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  EQFVFE 6
          EQFVFE
Sbjct: 70 EQFVFE 75
>NP_982272
          Length = 2099

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFVFESLV 9
           QF FES+V
Sbjct: 818 QFAFESVV 825
>NP_001177387
          Length = 1999

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFVFESLV 9
           QF FES+V
Sbjct: 750 QFAFESVV 757
>NP_001180465
          Length = 2031

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFVFESLV 9
           QF FES+V
Sbjct: 750 QFAFESVV 757
>NP_055325
          Length = 4935

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EQFVFESLV 9
            E +++ESLV
Sbjct: 1953 EDYIYESLV 1961
>NP_149015
          Length = 5142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EQFVFESLV 9
            E +++ESLV
Sbjct: 1953 EDYIYESLV 1961
>XP_006724204
          Length = 205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  EQFVFE 6
          EQFVFE
Sbjct: 70 EQFVFE 75
>XP_006715989
          Length = 5148

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EQFVFESLV 9
            E +++ESLV
Sbjct: 1953 EDYIYESLV 1961
>NP_001160135
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FVFESLV 9
           FVFESL+
Sbjct: 124 FVFESLL 130
>NP_072179
          Length = 870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           E+FVF+ L
Sbjct: 463 EEFVFDDL 470
>NP_002881
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           E+FVF+ L
Sbjct: 640 EEFVFDDL 647
>NP_055855
          Length = 2098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    QFVFESLV 9
            Q VFESL+
Sbjct: 1484 QSVFESLI 1491
>NP_001193581
          Length = 386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  EQFVFESL 8
          E+FV+E L
Sbjct: 76 EEFVYEKL 83
>NP_057093
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  EQFVFESL 8
          E+FV+E L
Sbjct: 76 EEFVYEKL 83
>NP_001193580
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  EQFVFESL 8
          E+FV+E L
Sbjct: 76 EEFVYEKL 83
>NP_006156
          Length = 1324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           EQF FE L
Sbjct: 233 EQFSFEDL 240
>XP_005271626
          Length = 1294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           EQF FE L
Sbjct: 292 EQFSFEDL 299
>XP_005271625
          Length = 1311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           EQF FE L
Sbjct: 220 EQFSFEDL 227
>XP_005271624
          Length = 1311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           EQF FE L
Sbjct: 220 EQFSFEDL 227
>XP_005271622
          Length = 1383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           EQF FE L
Sbjct: 292 EQFSFEDL 299
>XP_006712426
          Length = 1237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFVFESLV 9
           Q VFESL+
Sbjct: 790 QSVFESLI 797
>XP_006712425
          Length = 1349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFVFESLV 9
           Q VFESL+
Sbjct: 790 QSVFESLI 797
>XP_006712424
          Length = 1376

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QFVFESLV 9
           Q VFESL+
Sbjct: 790 QSVFESLI 797
>XP_006710735
          Length = 402

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  EQFVFESL 8
          E+FV+E L
Sbjct: 76 EEFVYEKL 83
>NP_060552
          Length = 1133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQFVFESLV 9
           E F+ ESLV
Sbjct: 622 EDFLHESLV 630
>NP_996809
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QFVFESL 8
           QFVFE +
Sbjct: 363 QFVFEEI 369
>NP_065184
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QFVFESL 8
           QFVFE +
Sbjct: 397 QFVFEEI 403
>NP_112503
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           E F++ES+
Sbjct: 357 ENFIYESM 364
>NP_000094
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           E F++ES+
Sbjct: 357 ENFIYESM 364
>NP_078959
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EQFVFESLV 9
           +QF+F+S++
Sbjct: 301 KQFLFDSIL 309
>NP_001231892
          Length = 2488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 2127 DSLVFESLI 2135
>NP_001154180
          Length = 1075

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQFVFESLV 9
           E F+ ESLV
Sbjct: 564 EDFLHESLV 572
>NP_001104488
          Length = 2365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 2004 DSLVFESLI 2012
>NP_001104489
          Length = 1493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 1132 DSLVFESLI 1140
>NP_795352
          Length = 1801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           E FV ESL
Sbjct: 948 ENFVMESL 955
>NP_057422
          Length = 975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           +QF++E L
Sbjct: 934 QQFIYEKL 941
>NP_660093
          Length = 2429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 2068 DSLVFESLI 2076
>NP_892009
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 2071 DSLVFESLI 2079
>XP_006722147
          Length = 245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EQFVFESLV 9
           +QF+F+S++
Sbjct: 186 KQFLFDSIL 194
>XP_006720469
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           E F++ES+
Sbjct: 255 ENFIYESM 262
>XP_005254249
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           E F++ES+
Sbjct: 298 ENFIYESM 305
>XP_005254248
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           E F++ES+
Sbjct: 357 ENFIYESM 364
>XP_005254247
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           E F++ES+
Sbjct: 357 ENFIYESM 364
>XP_006719561
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EQFVFESLV 9
           E F+ ESLV
Sbjct: 622 EDFLHESLV 630
>XP_006718432
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 1103 DSLVFESLI 1111
>XP_005253271
          Length = 1481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 1120 DSLVFESLI 1128
>XP_006718431
          Length = 1493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 1132 DSLVFESLI 1140
>XP_006718430
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 1190 DSLVFESLI 1198
>XP_006718429
          Length = 2416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 2055 DSLVFESLI 2063
>XP_006718428
          Length = 2455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 2094 DSLVFESLI 2102
>XP_006718427
          Length = 2465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EQFVFESLV 9
            +  VFESL+
Sbjct: 2104 DSLVFESLI 2112
>XP_006710341
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           E FV ESL
Sbjct: 948 ENFVMESL 955
>XP_005270404
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           E FV ESL
Sbjct: 948 ENFVMESL 955
>XP_005270402
          Length = 1454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           E FV ESL
Sbjct: 948 ENFVMESL 955
>XP_005270400
          Length = 1668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           E FV ESL
Sbjct: 948 ENFVMESL 955
>XP_006710340
          Length = 1815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           E FV ESL
Sbjct: 948 ENFVMESL 955
>XP_005270398
          Length = 1882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           E FV ESL
Sbjct: 948 ENFVMESL 955
>XP_006710339
          Length = 1896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           E FV ESL
Sbjct: 948 ENFVMESL 955
>XP_006710338
          Length = 1896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EQFVFESL 8
           E FV ESL
Sbjct: 948 ENFVMESL 955
>NP_001128251
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EQFVFESL 8
           +QF++E L
Sbjct: 974 QQFIYEKL 981
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.143    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 377,890
Number of extensions: 678
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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