Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_001275505                                                           17    2528
NP_001093881                                                           17    2528
NP_078857                                                              17    2528
NP_002069                                                              17    3301
NP_001166184                                                           17    3301
XP_005265132                                                           17    3301
XP_005265131                                                           17    3301
XP_006713173                                                           17    3301
XP_005265130                                                           17    3301
XP_005265129                                                           17    3301
XP_005265128                                                           17    3301
XP_005265127                                                           17    3301
XP_005265126                                                           17    3301
NP_009117                                                              17    4312
NP_115641                                                              17    4312
NP_001129518                                                           17    4312
NP_001254751                                                           17    4312
XP_005260322                                                           17    4312
XP_005260321                                                           17    4312
XP_005260320                                                           17    4312
XP_006723758                                                           17    4312
XP_006723757                                                           17    4312
XP_006723756                                                           17    4312
XP_006723755                                                           17    4312
XP_006723754                                                           17    4312
XP_006723753                                                           17    4312
XP_005260319                                                           17    4312
NP_060087                                                              16    5631
NP_203746                                                              16    7355
NP_001034795                                                           16    7355
NP_001153610                                                           16    7355
XP_006718796                                                           16    7355
XP_005274435                                                           16    7355
XP_006718795                                                           16    7355
XP_005274433                                                           16    7355
XP_005250656                                                           16    7355
XP_006716193                                                           16    7355
XP_006716192                                                           16    7355
XP_005250655                                                           16    7355
XP_005250654                                                           16    7355
XP_005250653                                                           16    7355
NP_001074295                                                           15    9605
NP_004716                                                              15    9605
NP_001007794                                                           15    9605
NP_001149946                                                           15    9605
NP_001275517                                                           15    9605
NP_068599                                                              15    9605
NP_001002843                                                           15    9605
NP_060131                                                              15    9605
NP_056052                                                              15    9605
NP_001074319                                                           15    9605
NP_071801                                                              15    9605
NP_114141                                                              15    9605
NP_877435                                                              15    9605
XP_005254541                                                           15    9605
XP_005254540                                                           15    9605
XP_005254538                                                           15    9605
XP_005274219                                                           15    9605
XP_005274218                                                           15    9605
XP_005272427                                                           15    9605
XP_005272426                                                           15    9605
XP_005250515                                                           15    9605
XP_005250514                                                           15    9605
XP_005248652                                                           15    9605
NP_061877                                                              15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            E NIQQKQS
Sbjct: 3123 EYNIQQKQS 3131
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            E NIQQKQS
Sbjct: 3115 EYNIQQKQS 3123
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            E NIQQKQS
Sbjct: 3076 EYNIQQKQS 3084
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            E NIQQKQS
Sbjct: 3155 EYNIQQKQS 3163
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            E NIQQKQS
Sbjct: 3168 EYNIQQKQS 3176
>NP_001275505
          Length = 936

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ENNIQQKQS 9
           EN++QQK S
Sbjct: 650 ENHLQQKHS 658
>NP_001093881
          Length = 971

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ENNIQQKQS 9
           EN++QQK S
Sbjct: 650 ENHLQQKHS 658
>NP_078857
          Length = 1140

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ENNIQQKQS 9
           EN++QQK S
Sbjct: 770 ENHLQQKHS 778
>NP_002069
          Length = 2230

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1822 KNNIQAKQN 1830
>NP_001166184
          Length = 2243

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1844 KNNIQAKQN 1852
>XP_005265132
          Length = 2214

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1806 KNNIQAKQN 1814
>XP_005265131
          Length = 2245

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1844 KNNIQAKQN 1852
>XP_006713173
          Length = 2250

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1842 KNNIQAKQN 1850
>XP_005265130
          Length = 2252

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1844 KNNIQAKQN 1852
>XP_005265129
          Length = 2269

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1861 KNNIQAKQN 1869
>XP_005265128
          Length = 2278

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1877 KNNIQAKQN 1885
>XP_005265127
          Length = 2283

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1877 KNNIQAKQN 1885
>XP_005265126
          Length = 2285

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            +NNIQ KQ+
Sbjct: 1877 KNNIQAKQN 1885
>NP_009117
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 2071 ENMIQEKQN 2079
>NP_115641
          Length = 703

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENNIQQKQS 9
           E NIQ KQS
Sbjct: 462 ELNIQNKQS 470
>NP_001129518
          Length = 742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENNIQQKQS 9
           E NIQ KQS
Sbjct: 501 ELNIQNKQS 509
>NP_001254751
          Length = 750

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENNIQQKQS 9
           E NIQ KQS
Sbjct: 501 ELNIQNKQS 509
>XP_005260322
          Length = 1810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 1439 ENMIQEKQN 1447
>XP_005260321
          Length = 2365

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 1994 ENMIQEKQN 2002
>XP_005260320
          Length = 2370

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 2071 ENMIQEKQN 2079
>XP_006723758
          Length = 2386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 2015 ENMIQEKQN 2023
>XP_006723757
          Length = 2404

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 2071 ENMIQEKQN 2079
>XP_006723756
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 2071 ENMIQEKQN 2079
>XP_006723755
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 2071 ENMIQEKQN 2079
>XP_006723754
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 2071 ENMIQEKQN 2079
>XP_006723753
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 2071 ENMIQEKQN 2079
>XP_005260319
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ENNIQQKQS 9
            EN IQ+KQ+
Sbjct: 2071 ENMIQEKQN 2079
>NP_060087
          Length = 2555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    NIQQKQS 9
            NIQQ+QS
Sbjct: 2401 NIQQQQS 2407
>NP_203746
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENNIQQKQS 9
           E+ +QQ+QS
Sbjct: 122 ESELQQRQS 130
>NP_001034795
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ENNIQQKQ 8
           EN+IQ+K+
Sbjct: 546 ENHIQRKE 553
>NP_001153610
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ENNIQQKQ 8
           EN+IQ+K+
Sbjct: 528 ENHIQRKE 535
>XP_006718796
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENNIQQKQS 9
           E+ +QQ+QS
Sbjct: 122 ESELQQRQS 130
>XP_005274435
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ENNIQQKQS 9
          E+ +QQ+QS
Sbjct: 16 ESELQQRQS 24
>XP_006718795
          Length = 598

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENNIQQKQS 9
           E+ +QQ+QS
Sbjct: 122 ESELQQRQS 130
>XP_005274433
          Length = 604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENNIQQKQS 9
           E+ +QQ+QS
Sbjct: 122 ESELQQRQS 130
>XP_005250656
          Length = 636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ENNIQQKQ 8
           EN+IQ+K+
Sbjct: 546 ENHIQRKE 553
>XP_006716193
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ENNIQQKQ 8
           EN+IQ+K+
Sbjct: 357 ENHIQRKE 364
>XP_006716192
          Length = 794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ENNIQQKQ 8
           EN+IQ+K+
Sbjct: 399 ENHIQRKE 406
>XP_005250655
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ENNIQQKQ 8
           EN+IQ+K+
Sbjct: 546 ENHIQRKE 553
>XP_005250654
          Length = 895

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ENNIQQKQ 8
           EN+IQ+K+
Sbjct: 546 ENHIQRKE 553
>XP_005250653
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ENNIQQKQ 8
           EN+IQ+K+
Sbjct: 546 ENHIQRKE 553
>NP_001074295
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NIQQKQS 9
            N+QQK+S
Sbjct: 1229 NLQQKKS 1235
>NP_004716
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENNIQQ 6
           ENNI+Q
Sbjct: 228 ENNIEQ 233
>NP_001007794
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENNIQQ 6
           ENNI+Q
Sbjct: 228 ENNIEQ 233
>NP_001149946
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENNIQQKQ 8
           EN I+Q+Q
Sbjct: 441 ENEIKQRQ 448
>NP_001275517
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNIQQKQS 9
           +N+Q+KQS
Sbjct: 592 SNMQKKQS 599
>NP_068599
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENNIQQKQ 8
           EN I+Q+Q
Sbjct: 351 ENEIKQRQ 358
>NP_001002843
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNIQQKQS 9
           +N+Q+KQS
Sbjct: 579 SNMQKKQS 586
>NP_060131
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNIQQKQS 9
           +N+Q+KQS
Sbjct: 592 SNMQKKQS 599
>NP_056052
          Length = 1354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENNIQQK 7
            EN+IQQ+
Sbjct: 1125 ENDIQQR 1131
>NP_001074319
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   ENNIQQK 7
           +NN+Q+K
Sbjct: 335 QNNLQEK 341
>NP_071801
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ENNIQQKQS 9
           EN +Q+K++
Sbjct: 290 ENQLQEKEN 298
>NP_114141
          Length = 5635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   IQQKQS 9
           IQQKQS
Sbjct: 160 IQQKQS 165
>NP_877435
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NNIQQKQ 8
           N+IQ+KQ
Sbjct: 194 NSIQEKQ 200
>XP_005254541
          Length = 890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNIQQKQS 9
           +N+Q+KQS
Sbjct: 756 SNMQKKQS 763
>XP_005254540
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNIQQKQS 9
           +N+Q+KQS
Sbjct: 756 SNMQKKQS 763
>XP_005254538
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNIQQKQS 9
           +N+Q+KQS
Sbjct: 756 SNMQKKQS 763
>XP_005274219
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENNIQQKQ 8
           EN I+Q+Q
Sbjct: 152 ENEIKQRQ 159
>XP_005274218
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENNIQQKQ 8
           EN I+Q+Q
Sbjct: 393 ENEIKQRQ 400
>XP_005272427
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NIQQKQS 9
            N+QQK+S
Sbjct: 1229 NLQQKKS 1235
>XP_005272426
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NIQQKQS 9
            N+QQK+S
Sbjct: 1229 NLQQKKS 1235
>XP_005250515
          Length = 1083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ENNIQQKQS 9
          ENN Q K+S
Sbjct: 25 ENNPQLKES 33
>XP_005250514
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ENNIQQKQS 9
          ENN Q K+S
Sbjct: 25 ENNPQLKES 33
>XP_005248652
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ENNIQQKQS 9
           EN +Q+K++
Sbjct: 290 ENQLQEKEN 298
>NP_061877
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ENNIQQKQS 9
          ENN Q K+S
Sbjct: 25 ENNPQLKES 33
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.284    0.103    0.235 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 595,752
Number of extensions: 1481
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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