Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_055660                                                              16    7355
NP_001017969                                                           16    7355
NP_055877                                                              16    7355
NP_001275656                                                           16    7355
NP_001275657                                                           16    7355
NP_001263347                                                           16    7355
NP_055681                                                              16    7355
NP_001026859                                                           16    7355
XP_006717794                                                           16    7355
XP_005269715                                                           16    7355
XP_006717793                                                           16    7355
XP_005269713                                                           16    7355
XP_005266194                                                           16    7355
XP_005266193                                                           16    7355
XP_005266191                                                           16    7355
XP_005266190                                                           16    7355
XP_005266189                                                           16    7355
XP_005251442                                                           16    7355
XP_006715685                                                           16    7355
NP_001231118                                                           15    9605
NP_001231121                                                           15    9605
NP_055564                                                              15    9605
NP_001231119                                                           15    9605
NP_001231120                                                           15    9605
NP_001231122                                                           15    9605
NP_064588                                                              15    9605
NP_001278112                                                           15    9605
NP_001171623                                                           15    9605
NP_001164120                                                           15    9605
NP_001164121                                                           15    9605
NP_112483                                                              15    9605
NP_803882                                                              15    9605
NP_001177719                                                           15    9605
XP_005262363                                                           15    9605
XP_005262362                                                           15    9605
XP_005262361                                                           15    9605
XP_005262360                                                           15    9605
XP_005262358                                                           15    9605
XP_006720406                                                           15    9605
XP_006720405                                                           15    9605
XP_006720404                                                           15    9605
XP_006720403                                                           15    9605
XP_006720402                                                           15    9605
XP_006720401                                                           15    9605
XP_006720400                                                           15    9605
XP_006720399                                                           15    9605
XP_006714341                                                           15    9605
XP_005246758                                                           15    9605
XP_005246757                                                           15    9605
XP_005246756                                                           15    9605
XP_005246755                                                           15    9605
XP_006712707                                                           15    9605
NP_258443                                                              15    9605
NP_001005203                                                           15    9605
NP_001010893                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ENLVSERE 8
            ENLVSERE
Sbjct: 1646 ENLVSERE 1653
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ENLVSERE 8
            ENLVSERE
Sbjct: 1646 ENLVSERE 1653
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ENLVSERE 8
            ENLVSERE
Sbjct: 1646 ENLVSERE 1653
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ENLVSERE 8
            ENLVSERE
Sbjct: 1646 ENLVSERE 1653
>NP_055660
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NLVSERE 8
           NLV ERE
Sbjct: 376 NLVKERE 382
>NP_001017969
          Length = 2103

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           ENL  +REG
Sbjct: 698 ENLQRKREG 706
>NP_055877
          Length = 1664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           E LVS REG
Sbjct: 153 ELLVSPREG 161
>NP_001275656
          Length = 1400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           E LVS REG
Sbjct: 153 ELLVSPREG 161
>NP_001275657
          Length = 1542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  ENLVSEREG 9
          E LVS REG
Sbjct: 33 ELLVSPREG 41
>NP_001263347
          Length = 2334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           ENL SE+ G
Sbjct: 385 ENLSSEKAG 393
>NP_055681
          Length = 2357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           ENL SE+ G
Sbjct: 385 ENLSSEKAG 393
>NP_001026859
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           EN  +E+EG
Sbjct: 628 ENFCNEKEG 636
>XP_006717794
          Length = 1194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           E LVS REG
Sbjct: 153 ELLVSPREG 161
>XP_005269715
          Length = 1230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           E LVS REG
Sbjct: 153 ELLVSPREG 161
>XP_006717793
          Length = 1603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           E LVS REG
Sbjct: 153 ELLVSPREG 161
>XP_005269713
          Length = 1646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           E LVS REG
Sbjct: 153 ELLVSPREG 161
>XP_005266194
          Length = 2379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           ENL SE+ G
Sbjct: 385 ENLSSEKAG 393
>XP_005266193
          Length = 2248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           ENL SE+ G
Sbjct: 533 ENLSSEKAG 541
>XP_005266191
          Length = 2379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           ENL SE+ G
Sbjct: 385 ENLSSEKAG 393
>XP_005266190
          Length = 2485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           ENL SE+ G
Sbjct: 533 ENLSSEKAG 541
>XP_005266189
          Length = 2505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           ENL SE+ G
Sbjct: 533 ENLSSEKAG 541
>XP_005251442
          Length = 2073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENLVSEREG 9
           ENL  +REG
Sbjct: 698 ENLQRKREG 706
>XP_006715685
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NLVSERE 8
           NLV ERE
Sbjct: 230 NLVKERE 236
>NP_001231118
          Length = 1644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 414 ENLLEEKE 421
>NP_001231121
          Length = 1504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 317 ENLLEEKE 324
>NP_055564
          Length = 1472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 361 ENLLEEKE 368
>NP_001231119
          Length = 1533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 346 ENLLEEKE 353
>NP_001231120
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 276 ENLLEEKE 283
>NP_001231122
          Length = 1347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 221 ENLLEEKE 228
>NP_064588
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  ENLVSERE 8
          EN+V ER+
Sbjct: 62 ENIVQERK 69
>NP_001278112
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           EN+V ER+
Sbjct: 93  ENIVQERK 100
>NP_001171623
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  ENLVSERE 8
          EN+V ER+
Sbjct: 62 ENIVQERK 69
>NP_001164120
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NLVSERE 8
           NL+SER+
Sbjct: 124 NLISERK 130
>NP_001164121
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  NLVSERE 8
          NL+SER+
Sbjct: 82 NLISERK 88
>NP_112483
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NLVSERE 8
           NL+SER+
Sbjct: 124 NLISERK 130
>NP_803882
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   NLVSEREG 9
           N++ ER+G
Sbjct: 237 NIIKERKG 244
>NP_001177719
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   ENLVSEREG 9
           EN+  ER G
Sbjct: 151 ENVAGERSG 159
>XP_005262363
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NLVSERE 8
           NL+SER+
Sbjct: 124 NLISERK 130
>XP_005262362
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NLVSERE 8
           NL+SER+
Sbjct: 124 NLISERK 130
>XP_005262361
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NLVSERE 8
           NL+SER+
Sbjct: 124 NLISERK 130
>XP_005262360
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NLVSERE 8
           NL+SER+
Sbjct: 124 NLISERK 130
>XP_005262358
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NLVSERE 8
           NL+SER+
Sbjct: 124 NLISERK 130
>XP_006720406
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 361 ENLLEEKE 368
>XP_006720405
          Length = 1347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 361 ENLLEEKE 368
>XP_006720404
          Length = 1477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 361 ENLLEEKE 368
>XP_006720403
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 361 ENLLEEKE 368
>XP_006720402
          Length = 1487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 361 ENLLEEKE 368
>XP_006720401
          Length = 1504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 361 ENLLEEKE 368
>XP_006720400
          Length = 1526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 361 ENLLEEKE 368
>XP_006720399
          Length = 1548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           ENL+ E+E
Sbjct: 361 ENLLEEKE 368
>XP_006714341
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENLVSERE 8
           EN+V ER+
Sbjct: 93  ENIVQERK 100
>XP_005246758
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  NLVSEREG 9
          N++ ER+G
Sbjct: 9  NIIKERKG 16
>XP_005246757
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  NLVSEREG 9
          N++ ER+G
Sbjct: 9  NIIKERKG 16
>XP_005246756
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   NLVSEREG 9
           N++ ER+G
Sbjct: 135 NIIKERKG 142
>XP_005246755
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   NLVSEREG 9
           N++ ER+G
Sbjct: 135 NIIKERKG 142
>XP_006712707
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   NLVSEREG 9
           N++ ER+G
Sbjct: 219 NIIKERKG 226
>NP_258443
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ENLVSE 6
           ENLVSE
Sbjct: 329 ENLVSE 334
>NP_001005203
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ENLVSERE 8
          ENL+S+R+
Sbjct: 83 ENLLSQRK 90
>NP_001010893
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NLVSEREG 9
          NLV++ EG
Sbjct: 89 NLVTDEEG 96
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293    0.122    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 520,613
Number of extensions: 924
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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