Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              20     509
XP_006713721                                                           20     509
NP_001714                                                              17    3301
XP_005249383                                                           17    3301
NP_001274268                                                           17    4312
NP_001073138                                                           17    4312
NP_112187                                                              17    4312
NP_001274266                                                           17    4312
NP_001274267                                                           17    4312
NP_001124322                                                           17    4312
NP_001124321                                                           17    4312
NP_037490                                                              17    4312
NP_057373                                                              17    4312
NP_055651                                                              16    5631
NP_001229288                                                           16    5631
XP_006718152                                                           16    5631
XP_006718151                                                           16    5631
XP_006718150                                                           16    5631
XP_006718149                                                           16    5631
XP_006718148                                                           16    5631
XP_006718147                                                           16    5631
NP_001073951                                                           16    5631
NP_001186068                                                           16    7355
NP_067032                                                              16    7355
NP_001186067                                                           16    7355
NP_060773                                                              16    7355
NP_055311                                                              16    7355
NP_009044                                                              16    7355
NP_065777                                                              16    7355
NP_055523                                                              16    7355
NP_001035847                                                           16    7355
NP_005125                                                              16    7355
XP_005262180                                                           16    7355
XP_006719769                                                           16    7355
XP_006715232                                                           16    7355
XP_005249381                                                           16    7355
XP_005249380                                                           16    7355
XP_005249379                                                           16    7355
XP_005249377                                                           16    7355
XP_005249376                                                           16    7355
XP_005249375                                                           16    7355
XP_005249374                                                           16    7355
XP_005249373                                                           16    7355
XP_005249372                                                           16    7355
XP_005249371                                                           16    7355
XP_005249370                                                           16    7355
XP_005249369                                                           16    7355
XP_005249368                                                           16    7355
XP_005249367                                                           16    7355
XP_006715205                                                           16    7355
XP_006715204                                                           16    7355
XP_006714724                                                           16    7355
XP_005248616                                                           16    7355
NP_008821                                                              15    9605
NP_001278414                                                           15    9605
NP_085125                                                              15    9605
NP_001008781                                                           15    9605
NP_001363                                                              15    9605
XP_005258487                                                           15    9605
XP_006717582                                                           15    9605
NP_004653                                                              15    9605
>NP_006209
          Length = 1068

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ENILNREIG 9
           E ILNREIG
Sbjct: 110 EKILNREIG 118
>XP_006713721
          Length = 1068

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ENILNREIG 9
           E ILNREIG
Sbjct: 110 EKILNREIG 118
>NP_001714
          Length = 2649

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    NILNREIG 9
            NI+N+E+G
Sbjct: 2545 NIINKEMG 2552
>XP_005249383
          Length = 3186

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    NILNREIG 9
            NI+N+E+G
Sbjct: 3082 NIINKEMG 3089
>NP_001274268
          Length = 337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILNREIG 9
           NIL R+IG
Sbjct: 103 NILRRQIG 110
>NP_001073138
          Length = 337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILNREIG 9
           NIL R+IG
Sbjct: 103 NILRRQIG 110
>NP_112187
          Length = 337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILNREIG 9
           NIL R+IG
Sbjct: 103 NILRRQIG 110
>NP_001274266
          Length = 337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILNREIG 9
           NIL R+IG
Sbjct: 103 NILRRQIG 110
>NP_001274267
          Length = 337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILNREIG 9
           NIL R+IG
Sbjct: 103 NILRRQIG 110
>NP_001124322
          Length = 341

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILNREIG 9
           NIL R+IG
Sbjct: 104 NILRRQIG 111
>NP_001124321
          Length = 341

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILNREIG 9
           NIL R+IG
Sbjct: 104 NILRRQIG 111
>NP_037490
          Length = 663

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NILNREIG 9
           N+L RE+G
Sbjct: 552 NVLKRELG 559
>NP_057373
          Length = 341

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILNREIG 9
           NIL R+IG
Sbjct: 104 NILRRQIG 111
>NP_055651
          Length = 696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENILNRE 7
           ENI+N+E
Sbjct: 450 ENIMNKE 456
>NP_001229288
          Length = 696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENILNRE 7
           ENI+N+E
Sbjct: 450 ENIMNKE 456
>XP_006718152
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENILNRE 7
           ENI+N+E
Sbjct: 450 ENIMNKE 456
>XP_006718151
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENILNRE 7
           ENI+N+E
Sbjct: 450 ENIMNKE 456
>XP_006718150
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENILNRE 7
           ENI+N+E
Sbjct: 450 ENIMNKE 456
>XP_006718149
          Length = 696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENILNRE 7
           ENI+N+E
Sbjct: 450 ENIMNKE 456
>XP_006718148
          Length = 696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENILNRE 7
           ENI+N+E
Sbjct: 450 ENIMNKE 456
>XP_006718147
          Length = 696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENILNRE 7
           ENI+N+E
Sbjct: 450 ENIMNKE 456
>NP_001073951
          Length = 976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENILNREI 8
           EN+L RE+
Sbjct: 470 ENLLGREV 477
>NP_001186068
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  NILNRE 7
          N+LNRE
Sbjct: 31 NVLNRE 36
>NP_067032
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  NILNRE 7
          N+LNRE
Sbjct: 31 NVLNRE 36
>NP_001186067
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  NILNRE 7
          N+LNRE
Sbjct: 31 NVLNRE 36
>NP_060773
          Length = 924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENILNR 6
           EN+LNR
Sbjct: 243 ENVLNR 248
>NP_055311
          Length = 745

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ENILNREIG 9
           ENIL  EIG
Sbjct: 202 ENILLDEIG 210
>NP_009044
          Length = 1943

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ENILNREIG 9
          +N+L RE G
Sbjct: 34 KNLLEREFG 42
>NP_065777
          Length = 704

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ENILNREIG 9
           E I+N E+G
Sbjct: 654 EGIMNPEVG 662
>NP_055523
          Length = 2209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NILNREI 8
           N+LN+EI
Sbjct: 855 NLLNKEI 861
>NP_001035847
          Length = 950

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  ENILNREI 8
          ENI NR++
Sbjct: 58 ENIFNRQM 65
>NP_005125
          Length = 933

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  ENILNREI 8
          ENI NR++
Sbjct: 41 ENIFNRQM 48
>XP_005262180
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  ENILNREIG 9
          ENIL  EIG
Sbjct: 81 ENILLDEIG 89
>XP_006719769
          Length = 2209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NILNREI 8
           N+LN+EI
Sbjct: 855 NLLNKEI 861
>XP_006715232
          Length = 7498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2697 ENLLNHEM 2704
>XP_005249381
          Length = 7281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2371 ENLLNHEM 2378
>XP_005249380
          Length = 7607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2697 ENLLNHEM 2704
>XP_005249379
          Length = 7633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2723 ENLLNHEM 2730
>XP_005249377
          Length = 7640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2730 ENLLNHEM 2737
>XP_005249376
          Length = 7647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2737 ENLLNHEM 2744
>XP_005249375
          Length = 7680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2770 ENLLNHEM 2777
>XP_005249374
          Length = 7709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2908 ENLLNHEM 2915
>XP_005249373
          Length = 7723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2813 ENLLNHEM 2820
>XP_005249372
          Length = 7785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2875 ENLLNHEM 2882
>XP_005249371
          Length = 7788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2908 ENLLNHEM 2915
>XP_005249370
          Length = 7794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2908 ENLLNHEM 2915
>XP_005249369
          Length = 7797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2887 ENLLNHEM 2894
>XP_005249368
          Length = 7812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2908 ENLLNHEM 2915
>XP_005249367
          Length = 7818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ENILNREI 8
            EN+LN E+
Sbjct: 2908 ENLLNHEM 2915
>XP_006715205
          Length = 924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENILNR 6
           EN+LNR
Sbjct: 243 ENVLNR 248
>XP_006715204
          Length = 924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENILNR 6
           EN+LNR
Sbjct: 243 ENVLNR 248
>XP_006714724
          Length = 681

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ENILNREIG 9
           E I+N E+G
Sbjct: 631 EGIMNPEVG 639
>XP_005248616
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ENILNREIG 9
           E I+N E+G
Sbjct: 636 EGIMNPEVG 644
>NP_008821
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ENILNREI 8
           EN++N E+
Sbjct: 128 ENLVNEEV 135
>NP_001278414
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ENILNREI 8
           EN++N E+
Sbjct: 128 ENLVNEEV 135
>NP_085125
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNREIG 9
           LNRE+G
Sbjct: 332 LNRELG 337
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ILNREI 8
           ILNREI
Sbjct: 116 ILNREI 121
>NP_001363
          Length = 4486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    NILNREI 8
            NIL REI
Sbjct: 4263 NILTREI 4269
>XP_005258487
          Length = 244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ENILNREI 8
           EN++N E+
Sbjct: 107 ENLVNEEV 114
>XP_006717582
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENILNREI 8
           +NIL RE+
Sbjct: 793 QNILKREL 800
>NP_004653
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NILNREI 8
           NIL REI
Sbjct: 575 NILTREI 581
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.143    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,297
Number of extensions: 730
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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