Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              18    1135
NP_653080                                                              18    1135
XP_005267292                                                           18    1135
XP_005267291                                                           18    1135
XP_005267290                                                           18    1135
NP_060833                                                              16    5631
NP_001026879                                                           16    5631
XP_005270007                                                           16    5631
XP_005270005                                                           16    5631
XP_005270003                                                           16    5631
NP_001935                                                              16    5631
NP_001138467                                                           16    7355
NP_000143                                                              15    9605
NP_001073271                                                           15    9605
NP_001073272                                                           15    9605
NP_055938                                                              15    9605
NP_001123910                                                           15    9605
NP_003118                                                              15    9605
NP_001182461                                                           15    9605
NP_055796                                                              15    9605
NP_001272376                                                           15    9605
NP_001272374                                                           15    9605
NP_001272373                                                           15    9605
NP_001070254                                                           15    9605
NP_775922                                                              15    9605
NP_055842                                                              15    9605
NP_001272377                                                           15    9605
XP_006726663                                                           15    9605
XP_006726662                                                           15    9605
XP_006726661                                                           15    9605
XP_006726660                                                           15    9605
XP_006726659                                                           15    9605
XP_006726658                                                           15    9605
XP_006725291                                                           15    9605
XP_006725290                                                           15    9605
XP_006725289                                                           15    9605
XP_006725288                                                           15    9605
XP_006725287                                                           15    9605
XP_006725286                                                           15    9605
XP_005257251                                                           15    9605
XP_005257250                                                           15    9605
XP_005255233                                                           15    9605
XP_006720928                                                           15    9605
XP_005255231                                                           15    9605
XP_005255230                                                           15    9605
XP_006718387                                                           15    9605
XP_006718386                                                           15    9605
XP_006717317                                                           15    9605
XP_006717316                                                           15    9605
XP_006717315                                                           15    9605
XP_006717314                                                           15    9605
XP_006717313                                                           15    9605
XP_006717312                                                           15    9605
XP_006717311                                                           15    9605
XP_006717310                                                           15    9605
XP_006717309                                                           15    9605
XP_006717308                                                           15    9605
XP_005264780                                                           15    9605
XP_006713127                                                           15    9605
XP_006713126                                                           15    9605
XP_005264779                                                           15    9605
XP_005264778                                                           15    9605
XP_005264777                                                           15    9605
NP_803173                                                              15    9605
>NP_005091
          Length = 1782

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ENIESSELV 9
            E+IESSELV
Sbjct: 1128 ESIESSELV 1136
>NP_653080
          Length = 1684

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ENIESSELV 9
            E+IESSELV
Sbjct: 1030 ESIESSELV 1038
>XP_005267292
          Length = 1677

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ENIESSELV 9
            E+IESSELV
Sbjct: 1023 ESIESSELV 1031
>XP_005267291
          Length = 1684

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ENIESSELV 9
            E+IESSELV
Sbjct: 1030 ESIESSELV 1038
>XP_005267290
          Length = 1782

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ENIESSELV 9
            E+IESSELV
Sbjct: 1128 ESIESSELV 1136
>NP_060833
          Length = 315

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NIESSEL 8
           NIESSE+
Sbjct: 232 NIESSEI 238
>NP_001026879
          Length = 342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NIESSEL 8
           NIESSE+
Sbjct: 232 NIESSEI 238
>XP_005270007
          Length = 232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NIESSEL 8
           NIESSE+
Sbjct: 149 NIESSEI 155
>XP_005270005
          Length = 259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NIESSEL 8
           NIESSE+
Sbjct: 149 NIESSEI 155
>XP_005270003
          Length = 306

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NIESSEL 8
           NIESSE+
Sbjct: 232 NIESSEI 238
>NP_001935
          Length = 999

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ENIESSELV 9
           ENI SSEL+
Sbjct: 278 ENILSSELL 286
>NP_001138467
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENIESSELV 9
           EN+E  ELV
Sbjct: 140 ENLELKELV 148
>NP_000143
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENIESSEL 8
           EN+ SSE+
Sbjct: 139 ENLSSSEM 146
>NP_001073271
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENIESSEL 8
           EN+ SSE+
Sbjct: 139 ENLSSSEM 146
>NP_001073272
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENIESSEL 8
           EN+ SSE+
Sbjct: 139 ENLSSSEM 146
>NP_055938
          Length = 1034

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            +N+ESSE
Sbjct: 1013 DNLESSE 1019
>NP_001123910
          Length = 2477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2406 ENVKSSE 2412
>NP_003118
          Length = 2472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2401 ENVKSSE 2407
>NP_001182461
          Length = 2452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2381 ENVKSSE 2387
>NP_055796
          Length = 1946

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN+ESS+
Sbjct: 1079 ENLESSQ 1085
>NP_001272376
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 566 DNVDAAELV 574
>NP_001272374
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 553 DNVDAAELV 561
>NP_001272373
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 554 DNVDAAELV 562
>NP_001070254
          Length = 1735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ENIESSE 7
            ENI SSE
Sbjct: 1307 ENISSSE 1313
>NP_775922
          Length = 6996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ENIESSELV 9
            ENI +SE++
Sbjct: 3203 ENIVASEII 3211
>NP_055842
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 581 DNVDAAELV 589
>NP_001272377
          Length = 697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 490 DNVDAAELV 498
>XP_006726663
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 554 DNVDAAELV 562
>XP_006726662
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 566 DNVDAAELV 574
>XP_006726661
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 572 DNVDAAELV 580
>XP_006726660
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 581 DNVDAAELV 589
>XP_006726659
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 590 DNVDAAELV 598
>XP_006726658
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 599 DNVDAAELV 607
>XP_006725291
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 554 DNVDAAELV 562
>XP_006725290
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 566 DNVDAAELV 574
>XP_006725289
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 572 DNVDAAELV 580
>XP_006725288
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 581 DNVDAAELV 589
>XP_006725287
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 590 DNVDAAELV 598
>XP_006725286
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 599 DNVDAAELV 607
>XP_005257251
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENIESSEL 8
           EN+ SSE+
Sbjct: 139 ENLSSSEM 146
>XP_005257250
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENIESSEL 8
           EN+ SSE+
Sbjct: 139 ENLSSSEM 146
>XP_005255233
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 566 DNVDAAELV 574
>XP_006720928
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 572 DNVDAAELV 580
>XP_005255231
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 590 DNVDAAELV 598
>XP_005255230
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ENIESSELV 9
           +N++++ELV
Sbjct: 599 DNVDAAELV 607
>XP_006718387
          Length = 1798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ENIESSE 7
            ENI SSE
Sbjct: 1370 ENISSSE 1376
>XP_006718386
          Length = 1822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ENIESSE 7
            ENI SSE
Sbjct: 1370 ENISSSE 1376
>XP_006717317
          Length = 2498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2427 ENVKSSE 2433
>XP_006717316
          Length = 2464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2393 ENVKSSE 2399
>XP_006717315
          Length = 2469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2398 ENVKSSE 2404
>XP_006717314
          Length = 2478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2407 ENVKSSE 2413
>XP_006717313
          Length = 2483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2412 ENVKSSE 2418
>XP_006717312
          Length = 2484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2413 ENVKSSE 2419
>XP_006717311
          Length = 2489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2418 ENVKSSE 2424
>XP_006717310
          Length = 2490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2419 ENVKSSE 2425
>XP_006717309
          Length = 2505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2434 ENVKSSE 2440
>XP_006717308
          Length = 2510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ENIESSE 7
            EN++SSE
Sbjct: 2439 ENVKSSE 2445
>XP_005264780
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENIESSE 7
           +N+ESSE
Sbjct: 665 DNLESSE 671
>XP_006713127
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENIESSE 7
           +N+ESSE
Sbjct: 724 DNLESSE 730
>XP_006713126
          Length = 980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENIESSE 7
           +N+ESSE
Sbjct: 959 DNLESSE 965
>XP_005264779
          Length = 989

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENIESSE 7
           +N+ESSE
Sbjct: 968 DNLESSE 974
>XP_005264778
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENIESSE 7
           +N+ESSE
Sbjct: 980 DNLESSE 986
>XP_005264777
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ENIESSE 7
           +N+ESSE
Sbjct: 982 DNLESSE 988
>NP_803173
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NIESSEL 8
           N+ESSE+
Sbjct: 222 NVESSEV 228
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.285    0.113    0.243 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 292,267
Number of extensions: 295
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package